SAT2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	31 studies	29% ± 12%	Explore
macrophage	27 studies	24% ± 9%	Explore
classical monocyte	24 studies	35% ± 15%	Explore
smooth muscle cell	21 studies	25% ± 7%	Explore
non-classical monocyte	21 studies	26% ± 13%	Explore
pericyte	21 studies	25% ± 8%	Explore
monocyte	18 studies	30% ± 8%	Explore
natural killer cell	18 studies	20% ± 6%	Explore
endothelial cell	17 studies	27% ± 9%	Explore
conventional dendritic cell	16 studies	27% ± 13%	Explore
endothelial cell of lymphatic vessel	15 studies	27% ± 9%	Explore
connective tissue cell	14 studies	31% ± 11%	Explore
epithelial cell	14 studies	34% ± 18%	Explore
B cell	12 studies	21% ± 4%	Explore
ciliated cell	12 studies	31% ± 13%	Explore
CD8-positive, alpha-beta T cell	11 studies	20% ± 4%	Explore
myofibroblast cell	11 studies	31% ± 10%	Explore
plasma cell	10 studies	32% ± 11%	Explore
basal cell	10 studies	27% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	20% ± 4%	Explore
mast cell	9 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	22% ± 5%	Explore
memory B cell	9 studies	19% ± 3%	Explore
myeloid cell	9 studies	26% ± 11%	Explore
dendritic cell	9 studies	30% ± 20%	Explore
type II pneumocyte	8 studies	34% ± 11%	Explore
mature NK T cell	8 studies	20% ± 4%	Explore
epithelial cell of proximal tubule	7 studies	50% ± 16%	Explore
abnormal cell	7 studies	26% ± 8%	Explore
enterocyte	7 studies	52% ± 21%	Explore
gamma-delta T cell	7 studies	21% ± 8%	Explore
alveolar macrophage	6 studies	20% ± 7%	Explore
neuron	6 studies	35% ± 13%	Explore
goblet cell	6 studies	21% ± 6%	Explore
naive B cell	6 studies	18% ± 2%	Explore
amacrine cell	6 studies	38% ± 18%	Explore
retinal rod cell	6 studies	29% ± 13%	Explore
endothelial cell of vascular tree	6 studies	25% ± 10%	Explore
astrocyte	6 studies	35% ± 14%	Explore
mucosal invariant T cell	6 studies	17% ± 1%	Explore
leukocyte	5 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
kidney loop of Henle epithelial cell	5 studies	24% ± 6%	Explore
progenitor cell	5 studies	30% ± 4%	Explore
T cell	5 studies	23% ± 6%	Explore
enteroendocrine cell	5 studies	35% ± 14%	Explore
mesothelial cell	5 studies	32% ± 15%	Explore
glutamatergic neuron	5 studies	40% ± 23%	Explore
innate lymphoid cell	5 studies	19% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	26% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	17% ± 2%	Explore
secretory cell	4 studies	25% ± 14%	Explore
pancreatic A cell	4 studies	23% ± 3%	Explore
type B pancreatic cell	4 studies	33% ± 10%	Explore
CD4-positive, alpha-beta T cell	4 studies	24% ± 2%	Explore
exhausted T cell	4 studies	22% ± 6%	Explore
plasmablast	4 studies	32% ± 15%	Explore
intestinal crypt stem cell	4 studies	20% ± 4%	Explore
retinal ganglion cell	4 studies	60% ± 25%	Explore
club cell	4 studies	24% ± 9%	Explore
retina horizontal cell	4 studies	43% ± 19%	Explore
microglial cell	4 studies	26% ± 9%	Explore
cardiac muscle cell	4 studies	22% ± 3%	Explore
intermediate monocyte	4 studies	42% ± 19%	Explore
adipocyte	4 studies	35% ± 13%	Explore
hepatocyte	4 studies	44% ± 28%	Explore
regulatory T cell	4 studies	19% ± 3%	Explore
plasmacytoid dendritic cell	4 studies	24% ± 7%	Explore
ionocyte	3 studies	26% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	36% ± 6%	Explore
neural crest cell	3 studies	21% ± 2%	Explore
retinal bipolar neuron	3 studies	42% ± 13%	Explore
OFF-bipolar cell	3 studies	40% ± 15%	Explore
retinal cone cell	3 studies	58% ± 17%	Explore
retinal pigment epithelial cell	3 studies	41% ± 23%	Explore
Mueller cell	3 studies	38% ± 10%	Explore
type I pneumocyte	3 studies	22% ± 8%	Explore
GABAergic neuron	3 studies	40% ± 13%	Explore
oligodendrocyte	3 studies	22% ± 4%	Explore
glial cell	3 studies	32% ± 15%	Explore
melanocyte	3 studies	29% ± 8%	Explore
mononuclear phagocyte	3 studies	34% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	26% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	20% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	23% ± 7%	Explore
lung	11 studies	30% ± 11%	Explore
kidney	8 studies	27% ± 11%	Explore
brain	8 studies	29% ± 17%	Explore
eye	8 studies	33% ± 12%	Explore
intestine	7 studies	35% ± 13%	Explore
liver	5 studies	22% ± 6%	Explore
pancreas	4 studies	28% ± 7%	Explore
uterus	4 studies	27% ± 15%	Explore
breast	4 studies	18% ± 3%	Explore
bone marrow	3 studies	17% ± 1%	Explore
lymph node	3 studies	21% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	7444.53	226 / 226	100%	209.92	406 / 406
pancreas	100%	3014.02	328 / 328	100%	73.20	178 / 178
skin	100%	2115.86	1808 / 1809	100%	104.01	472 / 472
brain	100%	3354.90	2638 / 2642	100%	182.29	705 / 705
thymus	100%	4283.83	653 / 653	100%	132.30	604 / 605
kidney	100%	7619.99	89 / 89	100%	93.89	897 / 901
prostate	100%	4178.96	245 / 245	99%	147.37	499 / 502
adrenal gland	100%	10137.88	258 / 258	99%	133.48	228 / 230
bladder	100%	3251.86	21 / 21	99%	73.87	497 / 504
lung	100%	2757.19	577 / 578	98%	58.84	1133 / 1155
breast	100%	3222.06	459 / 459	98%	61.27	1091 / 1118
uterus	100%	3629.45	170 / 170	97%	66.35	447 / 459
intestine	100%	3762.86	966 / 966	97%	51.64	513 / 527
stomach	100%	2926.58	359 / 359	97%	44.47	276 / 286
ovary	100%	6618.67	180 / 180	95%	43.52	407 / 430
esophagus	100%	2853.35	1445 / 1445	93%	35.29	171 / 183
adipose	100%	3215.07	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	174.64	80 / 80
lymph node	0%	0	0 / 0	100%	72.24	29 / 29
spleen	100%	4119.90	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	37.55	1 / 1
muscle	100%	2350.19	802 / 803	0%	0	0 / 0
blood vessel	100%	2333.57	1333 / 1335	0%	0	0 / 0
heart	98%	2381.20	842 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	41.20	43 / 45
peripheral blood	93%	1372.38	866 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0046204	Biological process	nor-spermidine metabolic process
GO_0032918	Biological process	spermidine acetylation
GO_0032920	Biological process	putrescine acetylation
GO_0032919	Biological process	spermine acetylation
GO_0006596	Biological process	polyamine biosynthetic process
GO_0070062	Cellular component	extracellular exosome
GO_0005737	Cellular component	cytoplasm
GO_0004145	Molecular function	diamine N-acetyltransferase activity
GO_0008080	Molecular function	N-acetyltransferase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SAT2
Protein name	Spermidine/spermine N1-acetyltransferase family member 2 SAT2 protein Thialysine N-epsilon-acetyltransferase (EC 2.3.1.-) (Diamine acetyltransferase 2) (EC 2.3.1.57) (Spermidine/spermine N(1)-acetyltransferase 2) (SSAT-2)
Synonyms	SSAT2
Description	FUNCTION: Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur . May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine . However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo . .
Accessions	I3L0W4 ENST00000571074.5 Q502X4 Q96F10 I3L2W7 ENST00000269298.10 ENST00000573566.1 ENST00000575826.5

SAT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review