PABPC4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	29 studies	32% ± 11%	Explore
conventional dendritic cell	22 studies	31% ± 14%	Explore
B cell	20 studies	22% ± 6%	Explore
non-classical monocyte	19 studies	38% ± 15%	Explore
classical monocyte	17 studies	25% ± 10%	Explore
fibroblast	16 studies	23% ± 11%	Explore
plasma cell	15 studies	38% ± 15%	Explore
smooth muscle cell	14 studies	21% ± 4%	Explore
pericyte	14 studies	22% ± 5%	Explore
mast cell	12 studies	29% ± 10%	Explore
basal cell	12 studies	27% ± 12%	Explore
dendritic cell	11 studies	33% ± 17%	Explore
monocyte	11 studies	28% ± 10%	Explore
CD4-positive, alpha-beta T cell	11 studies	22% ± 7%	Explore
memory B cell	10 studies	22% ± 6%	Explore
natural killer cell	9 studies	18% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	26% ± 6%	Explore
endothelial cell	8 studies	27% ± 8%	Explore
myeloid cell	8 studies	34% ± 16%	Explore
epithelial cell	8 studies	36% ± 21%	Explore
T cell	7 studies	23% ± 4%	Explore
alveolar macrophage	7 studies	23% ± 7%	Explore
plasmablast	7 studies	45% ± 18%	Explore
leukocyte	7 studies	26% ± 7%	Explore
naive B cell	7 studies	20% ± 4%	Explore
IgA plasma cell	7 studies	33% ± 17%	Explore
connective tissue cell	7 studies	20% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	26% ± 9%	Explore
microglial cell	6 studies	31% ± 16%	Explore
gamma-delta T cell	6 studies	24% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	24% ± 9%	Explore
secretory cell	5 studies	28% ± 8%	Explore
mononuclear phagocyte	5 studies	38% ± 12%	Explore
abnormal cell	5 studies	27% ± 9%	Explore
myofibroblast cell	5 studies	19% ± 4%	Explore
retinal cone cell	5 studies	39% ± 18%	Explore
CD8-positive, alpha-beta T cell	5 studies	18% ± 3%	Explore
T follicular helper cell	5 studies	22% ± 4%	Explore
hematopoietic precursor cell	4 studies	33% ± 11%	Explore
IgG plasma cell	4 studies	24% ± 2%	Explore
innate lymphoid cell	4 studies	25% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	21% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	22% ± 9%	Explore
regulatory T cell	4 studies	18% ± 3%	Explore
type I pneumocyte	3 studies	25% ± 8%	Explore
club cell	3 studies	22% ± 7%	Explore
respiratory goblet cell	3 studies	26% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
neural crest cell	3 studies	21% ± 6%	Explore
retinal rod cell	3 studies	29% ± 8%	Explore
type II pneumocyte	3 studies	23% ± 9%	Explore
tissue-resident macrophage	3 studies	31% ± 15%	Explore
ciliated cell	3 studies	38% ± 5%	Explore
inflammatory macrophage	3 studies	37% ± 12%	Explore
muscle cell	3 studies	24% ± 6%	Explore
acinar cell	3 studies	63% ± 11%	Explore
brush cell	3 studies	20% ± 2%	Explore
goblet cell	3 studies	22% ± 3%	Explore
intestinal crypt stem cell	3 studies	21% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	19% ± 2%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	53% ± 21%	Explore
erythroblast	3 studies	55% ± 21%	Explore
plasmacytoid dendritic cell	3 studies	23% ± 7%	Explore
hepatocyte	3 studies	53% ± 24%	Explore
oligodendrocyte precursor cell	3 studies	18% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	10 studies	24% ± 9%	Explore
peripheral blood	10 studies	24% ± 7%	Explore
intestine	7 studies	22% ± 7%	Explore
liver	6 studies	30% ± 13%	Explore
eye	5 studies	25% ± 7%	Explore
brain	5 studies	25% ± 4%	Explore
uterus	4 studies	27% ± 12%	Explore
bone marrow	3 studies	23% ± 10%	Explore
lymph node	3 studies	25% ± 5%	Explore
pancreas	3 studies	31% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	9482.10	21 / 21	100%	64.54	504 / 504
ovary	100%	12256.24	180 / 180	100%	85.92	430 / 430
pancreas	100%	23612.90	328 / 328	100%	41.63	178 / 178
stomach	100%	11038.74	359 / 359	100%	46.87	286 / 286
esophagus	100%	6686.09	1444 / 1445	100%	61.92	183 / 183
skin	100%	9567.28	1807 / 1809	100%	70.11	472 / 472
intestine	100%	7763.16	966 / 966	100%	44.81	526 / 527
prostate	100%	6560.47	245 / 245	100%	47.52	501 / 502
uterus	100%	8022.14	170 / 170	100%	58.08	458 / 459
lung	100%	7955.23	576 / 578	100%	49.67	1155 / 1155
breast	100%	7938.07	459 / 459	100%	43.12	1114 / 1118
thymus	100%	6350.72	652 / 653	100%	41.02	603 / 605
kidney	100%	4801.90	89 / 89	99%	32.10	894 / 901
adrenal gland	100%	8910.77	258 / 258	99%	46.15	228 / 230
liver	100%	4333.54	225 / 226	100%	30.07	404 / 406
brain	87%	2711.33	2311 / 2642	100%	28.15	705 / 705
adipose	100%	9485.70	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	84.78	80 / 80
lymph node	0%	0	0 / 0	100%	62.37	29 / 29
muscle	100%	31230.15	803 / 803	0%	0	0 / 0
spleen	100%	7297.57	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	37.24	45 / 45
ureter	0%	0	0 / 0	100%	43.95	1 / 1
blood vessel	100%	7293.50	1334 / 1335	0%	0	0 / 0
heart	95%	9304.79	822 / 861	0%	0	0 / 0
peripheral blood	77%	6134.03	718 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006412	Biological process	translation
GO_0006401	Biological process	RNA catabolic process
GO_0007596	Biological process	blood coagulation
GO_0043488	Biological process	regulation of mRNA stability
GO_0006396	Biological process	RNA processing
GO_0061515	Biological process	myeloid cell development
GO_0005829	Cellular component	cytosol
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0010494	Cellular component	cytoplasmic stress granule
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0008143	Molecular function	poly(A) binding
GO_0017130	Molecular function	poly(C) RNA binding
GO_0003730	Molecular function	mRNA 3'-UTR binding
GO_0008266	Molecular function	poly(U) RNA binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	PABPC4
Protein name	Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) Polyadenylate-binding protein (PABP) Poly(A) binding protein cytoplasmic 4 PABPC4 protein
Synonyms	APP1 PABP4 hCG_2031827
Description	FUNCTION: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). . FUNCTION: Binds the poly(A) tail of mRNA. . FUNCTION: Binds the poly(A) tail of mRNA. . FUNCTION: Binds the poly(A) tail of mRNA. . FUNCTION: Binds the poly(A) tail of mRNA. . FUNCTION: Binds the poly(A) tail of mRNA. . FUNCTION: Binds the poly(A) tail of mRNA. .
Accessions	ENST00000451091.2 ENST00000677609.1 A0A7I2V5F4 ENST00000372856.7 [Q13310-2] ENST00000372862.7 ENST00000678469.1 ENST00000372858.8 [Q13310-3] A0A7I2V4V6 ENST00000678625.1 A0A7I2V598 B1ANR1 H0Y6X6 H0Y5F5 H0YEQ8 ENST00000474378.1 A0A7I2V4L7 Q3B867 H0YER0 Q147Y3 ENST00000437136.5 Q6IQ30 ENST00000470443.6 Q13310 B1ANR0 H0YEU6 ENST00000527718.2 ENST00000676859.1 ENST00000530186.1 H0YCC8 ENST00000421687.6 ENST00000677006.1 ENST00000372857.7 [Q13310-1] A0A7I2V5W9

PABPC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review