MT1X | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	29 studies	38% ± 15%	Explore
endothelial cell	28 studies	34% ± 13%	Explore
CD8-positive, alpha-beta T cell	26 studies	26% ± 9%	Explore
smooth muscle cell	22 studies	42% ± 22%	Explore
basal cell	22 studies	52% ± 17%	Explore
pericyte	20 studies	44% ± 19%	Explore
regulatory T cell	19 studies	23% ± 6%	Explore
T cell	18 studies	25% ± 8%	Explore
epithelial cell	17 studies	40% ± 18%	Explore
CD4-positive, alpha-beta T cell	17 studies	23% ± 11%	Explore
classical monocyte	16 studies	24% ± 7%	Explore
astrocyte	15 studies	36% ± 18%	Explore
macrophage	14 studies	24% ± 8%	Explore
natural killer cell	11 studies	24% ± 10%	Explore
endothelial cell of lymphatic vessel	11 studies	33% ± 8%	Explore
capillary endothelial cell	10 studies	46% ± 15%	Explore
endothelial cell of vascular tree	10 studies	47% ± 21%	Explore
monocyte	9 studies	22% ± 7%	Explore
gamma-delta T cell	9 studies	24% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	24% ± 5%	Explore
endothelial cell of artery	8 studies	50% ± 20%	Explore
enterocyte	8 studies	47% ± 21%	Explore
goblet cell	8 studies	50% ± 17%	Explore
myofibroblast cell	8 studies	54% ± 26%	Explore
vein endothelial cell	8 studies	46% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	20% ± 2%	Explore
mature NK T cell	7 studies	21% ± 8%	Explore
ciliated cell	7 studies	35% ± 23%	Explore
T follicular helper cell	7 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	28% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	29% ± 10%	Explore
club cell	6 studies	40% ± 10%	Explore
connective tissue cell	6 studies	35% ± 13%	Explore
non-classical monocyte	6 studies	26% ± 9%	Explore
epithelial cell of proximal tubule	6 studies	59% ± 24%	Explore
abnormal cell	6 studies	33% ± 14%	Explore
mucosal invariant T cell	6 studies	22% ± 3%	Explore
myeloid cell	6 studies	24% ± 9%	Explore
adipocyte	6 studies	27% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	21% ± 5%	Explore
ionocyte	5 studies	41% ± 12%	Explore
respiratory goblet cell	5 studies	30% ± 9%	Explore
secretory cell	5 studies	48% ± 22%	Explore
hepatocyte	5 studies	67% ± 38%	Explore
kidney loop of Henle epithelial cell	5 studies	32% ± 8%	Explore
progenitor cell	5 studies	49% ± 20%	Explore
transit amplifying cell	5 studies	45% ± 20%	Explore
mesothelial cell	5 studies	50% ± 28%	Explore
dendritic cell	5 studies	24% ± 8%	Explore
type I pneumocyte	4 studies	25% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	24% ± 8%	Explore
exhausted T cell	4 studies	31% ± 2%	Explore
glomerular endothelial cell	4 studies	41% ± 13%	Explore
intestinal crypt stem cell	4 studies	59% ± 23%	Explore
retinal ganglion cell	4 studies	56% ± 27%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	17% ± 1%	Explore
adventitial cell	4 studies	60% ± 7%	Explore
type II pneumocyte	4 studies	23% ± 8%	Explore
Mueller cell	4 studies	57% ± 24%	Explore
keratinocyte	4 studies	71% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 0%	Explore
duct epithelial cell	3 studies	26% ± 11%	Explore
endothelial cell of sinusoid	3 studies	25% ± 5%	Explore
conventional dendritic cell	3 studies	28% ± 2%	Explore
renal alpha-intercalated cell	3 studies	45% ± 5%	Explore
lymphocyte	3 studies	29% ± 11%	Explore
pro-B cell	3 studies	28% ± 6%	Explore
erythrocyte	3 studies	30% ± 11%	Explore
retinal pigment epithelial cell	3 studies	33% ± 20%	Explore
glial cell	3 studies	20% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	29% ± 5%	Explore
luminal cell of prostate epithelium	3 studies	48% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	21% ± 5%	Explore
T-helper 17 cell	3 studies	18% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	25% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	35% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	47% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	28% ± 12%	Explore
intestine	11 studies	26% ± 18%	Explore
peripheral blood	8 studies	22% ± 3%	Explore
kidney	8 studies	31% ± 13%	Explore
eye	6 studies	25% ± 6%	Explore
liver	5 studies	27% ± 18%	Explore
uterus	5 studies	28% ± 8%	Explore
pancreas	4 studies	26% ± 6%	Explore
prostate	4 studies	39% ± 3%	Explore
breast	4 studies	38% ± 12%	Explore
adrenal gland	3 studies	23% ± 4%	Explore
lymph node	3 studies	22% ± 4%	Explore
skin	3 studies	43% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	96%	15539.79	628 / 653	95%	61.26	572 / 605
pancreas	87%	13498.73	286 / 328	90%	27.93	160 / 178
liver	96%	30658.00	217 / 226	60%	51.42	244 / 406
esophagus	70%	9053.53	1015 / 1445	83%	38.69	151 / 183
prostate	63%	7269.16	155 / 245	83%	26.60	415 / 502
breast	83%	15138.80	380 / 459	57%	14.73	638 / 1118
lung	69%	7805.59	397 / 578	69%	21.58	795 / 1155
brain	38%	2769.00	1007 / 2642	97%	91.24	686 / 705
stomach	74%	7612.48	265 / 359	54%	10.36	155 / 286
ovary	32%	2068.82	57 / 180	91%	33.19	393 / 430
kidney	79%	8440.38	70 / 89	43%	19.06	384 / 901
skin	83%	17534.64	1498 / 1809	33%	6.11	157 / 472
muscle	98%	51295.78	783 / 803	0%	0	0 / 0
intestine	35%	3661.68	336 / 966	63%	13.63	330 / 527
uterus	18%	1524.64	31 / 170	78%	46.27	360 / 459
bladder	33%	2280.86	7 / 21	55%	18.88	275 / 504
blood vessel	85%	16825.26	1139 / 1335	0%	0	0 / 0
adipose	81%	17882.03	973 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	80%	37.25	36 / 45
lymph node	0%	0	0 / 0	62%	10.64	18 / 29
adrenal gland	24%	1219.30	63 / 258	30%	9.76	68 / 230
heart	39%	2888.14	338 / 861	0%	0	0 / 0
peripheral blood	2%	251.52	22 / 929	0%	0	0 / 0
spleen	2%	94.75	4 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	1%	1.24	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0071294	Biological process	cellular response to zinc ion
GO_0036018	Biological process	cellular response to erythropoietin
GO_0071276	Biological process	cellular response to cadmium ion
GO_0010038	Biological process	response to metal ion
GO_0071280	Biological process	cellular response to copper ion
GO_0010273	Biological process	detoxification of copper ion
GO_0045926	Biological process	negative regulation of growth
GO_0006882	Biological process	intracellular zinc ion homeostasis
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	MT1X
Protein name	Metallothionein Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX)
Synonyms
Description	FUNCTION: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling . . FUNCTION: Metallothioneins have a high content of cysteine residues that bind various heavy metals. . FUNCTION: Metallothioneins have a high content of cysteine residues that bind various heavy metals. .
Accessions	P80297 ENST00000564974.1 Q8WVB5 ENST00000562939.1 U3KQD7 ENST00000394485.5

MT1X report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review