MSI2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	24 studies	41% ± 21%	Explore
astrocyte	21 studies	81% ± 16%	Explore
ciliated cell	19 studies	50% ± 19%	Explore
mast cell	17 studies	34% ± 13%	Explore
B cell	14 studies	31% ± 12%	Explore
oligodendrocyte precursor cell	14 studies	57% ± 21%	Explore
microglial cell	14 studies	46% ± 17%	Explore
oligodendrocyte	13 studies	35% ± 14%	Explore
fibroblast	13 studies	32% ± 16%	Explore
regulatory T cell	13 studies	24% ± 11%	Explore
epithelial cell	12 studies	41% ± 28%	Explore
T cell	11 studies	26% ± 10%	Explore
basal cell	11 studies	40% ± 23%	Explore
GABAergic neuron	11 studies	54% ± 21%	Explore
smooth muscle cell	10 studies	31% ± 13%	Explore
glutamatergic neuron	9 studies	45% ± 23%	Explore
pericyte	9 studies	31% ± 11%	Explore
retinal cone cell	9 studies	73% ± 24%	Explore
plasma cell	9 studies	42% ± 23%	Explore
club cell	8 studies	39% ± 20%	Explore
amacrine cell	8 studies	59% ± 19%	Explore
retinal rod cell	8 studies	66% ± 22%	Explore
adipocyte	8 studies	28% ± 9%	Explore
CD4-positive, alpha-beta T cell	7 studies	31% ± 9%	Explore
CD8-positive, alpha-beta T cell	7 studies	26% ± 8%	Explore
kidney loop of Henle epithelial cell	7 studies	42% ± 28%	Explore
renal alpha-intercalated cell	7 studies	71% ± 15%	Explore
neuron	7 studies	47% ± 24%	Explore
retinal ganglion cell	7 studies	66% ± 20%	Explore
hematopoietic stem cell	7 studies	45% ± 20%	Explore
mesothelial cell	7 studies	42% ± 12%	Explore
respiratory goblet cell	6 studies	45% ± 23%	Explore
kidney distal convoluted tubule epithelial cell	6 studies	52% ± 29%	Explore
abnormal cell	6 studies	28% ± 19%	Explore
interneuron	6 studies	64% ± 19%	Explore
precursor B cell	6 studies	48% ± 16%	Explore
retina horizontal cell	6 studies	79% ± 16%	Explore
Mueller cell	6 studies	82% ± 20%	Explore
type II pneumocyte	6 studies	24% ± 6%	Explore
natural killer cell	5 studies	24% ± 6%	Explore
hematopoietic precursor cell	5 studies	52% ± 24%	Explore
ionocyte	5 studies	42% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	29% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	26% ± 10%	Explore
capillary endothelial cell	5 studies	26% ± 10%	Explore
retinal bipolar neuron	5 studies	50% ± 10%	Explore
macrophage	5 studies	38% ± 15%	Explore
renal principal cell	5 studies	47% ± 21%	Explore
pro-B cell	5 studies	49% ± 15%	Explore
brush cell	5 studies	44% ± 18%	Explore
cardiac muscle cell	5 studies	59% ± 15%	Explore
monocyte	5 studies	20% ± 5%	Explore
goblet cell	5 studies	42% ± 26%	Explore
deuterosomal cell	4 studies	26% ± 4%	Explore
secretory cell	4 studies	25% ± 5%	Explore
plasmablast	4 studies	39% ± 23%	Explore
podocyte	4 studies	54% ± 25%	Explore
progenitor cell	4 studies	41% ± 20%	Explore
glial cell	4 studies	38% ± 18%	Explore
granule cell	4 studies	48% ± 11%	Explore
retinal pigment epithelial cell	4 studies	54% ± 24%	Explore
lymphocyte	4 studies	41% ± 11%	Explore
OFF-bipolar cell	4 studies	55% ± 10%	Explore
ON-bipolar cell	4 studies	54% ± 9%	Explore
T follicular helper cell	4 studies	19% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	19% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore
cholangiocyte	3 studies	45% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	27% ± 7%	Explore
glomerular endothelial cell	3 studies	43% ± 10%	Explore
connective tissue cell	3 studies	41% ± 19%	Explore
renal beta-intercalated cell	3 studies	69% ± 35%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	50% ± 6%	Explore
GABAergic interneuron	3 studies	53% ± 10%	Explore
placental villous trophoblast	3 studies	24% ± 7%	Explore
endocardial cell	3 studies	31% ± 11%	Explore
GABAergic amacrine cell	3 studies	66% ± 7%	Explore
glycinergic amacrine cell	3 studies	53% ± 3%	Explore
rod bipolar cell	3 studies	61% ± 10%	Explore
erythroblast	3 studies	25% ± 11%	Explore
innate lymphoid cell	3 studies	27% ± 16%	Explore
endothelial cell of vascular tree	3 studies	26% ± 13%	Explore
hepatocyte	3 studies	46% ± 20%	Explore
type I pneumocyte	3 studies	22% ± 4%	Explore
dendritic cell	3 studies	25% ± 7%	Explore
neural progenitor cell	3 studies	66% ± 33%	Explore
ependymal cell	3 studies	92% ± 3%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	64% ± 5%	Explore
enteroendocrine cell	3 studies	35% ± 12%	Explore
alveolar macrophage	3 studies	19% ± 4%	Explore
leukocyte	3 studies	54% ± 12%	Explore
immature B cell	3 studies	53% ± 10%	Explore
mural cell	3 studies	50% ± 6%	Explore
mucus secreting cell	3 studies	54% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	45% ± 17%	Explore
lung	10 studies	24% ± 7%	Explore
eye	10 studies	60% ± 22%	Explore
kidney	5 studies	47% ± 23%	Explore
heart	5 studies	35% ± 13%	Explore
peripheral blood	3 studies	34% ± 19%	Explore
liver	3 studies	35% ± 22%	Explore
bone marrow	3 studies	26% ± 9%	Explore
intestine	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	7434.36	2641 / 2642	100%	37.18	704 / 705
prostate	100%	4989.56	245 / 245	99%	15.11	495 / 502
stomach	100%	2469.34	359 / 359	99%	13.75	282 / 286
thymus	100%	5616.64	653 / 653	98%	20.90	595 / 605
intestine	100%	3077.26	965 / 966	98%	14.65	518 / 527
adrenal gland	100%	14613.02	258 / 258	97%	18.56	224 / 230
kidney	100%	6633.91	89 / 89	97%	18.22	874 / 901
lung	98%	2410.45	568 / 578	96%	13.95	1111 / 1155
bladder	100%	4565.48	21 / 21	93%	13.58	467 / 504
breast	95%	3120.74	438 / 459	97%	23.66	1087 / 1118
ovary	100%	12372.12	180 / 180	92%	9.60	396 / 430
skin	95%	1940.15	1726 / 1809	96%	19.12	454 / 472
esophagus	99%	2922.60	1437 / 1445	92%	12.49	168 / 183
pancreas	92%	1646.11	303 / 328	95%	9.87	169 / 178
uterus	100%	3039.77	170 / 170	84%	9.32	384 / 459
liver	75%	951.51	169 / 226	41%	3.66	167 / 406
muscle	100%	6863.36	803 / 803	0%	0	0 / 0
spleen	100%	4095.29	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	8.40	1 / 1
blood vessel	99%	2432.62	1315 / 1335	0%	0	0 / 0
heart	96%	3970.64	828 / 861	0%	0	0 / 0
adipose	94%	1590.74	1127 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	91%	14.09	73 / 80
lymph node	0%	0	0 / 0	90%	8.70	26 / 29
tonsil	0%	0	0 / 0	80%	8.04	36 / 45
peripheral blood	51%	1950.05	478 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007417	Biological process	central nervous system development
GO_0048864	Biological process	stem cell development
GO_0006417	Biological process	regulation of translation
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0008266	Molecular function	poly(U) RNA binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0003729	Molecular function	mRNA binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	MSI2
Protein name	Musashi RNA binding protein 2 (cDNA FLJ56904, highly similar to RNA-binding protein Musashi homolog 2) Musashi RNA binding protein 2 (cDNA FLJ52888, highly similar to RNA-binding protein Musashi homolog 2) Musashi RNA binding protein 2 RNA-binding protein Musashi homolog 2 (Musashi-2)
Synonyms
Description	FUNCTION: RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). .
Accessions	A0A6Q8PFI2 ENST00000674898.1 ENST00000284073.7 [Q96DH6-1] ENST00000674961.1 ENST00000416426.6 J3QKT5 ENST00000675127.1 B4DM51 ENST00000581776.5 ENST00000674574.1 A0A6Q8PGD8 ENST00000676105.1 ENST00000675656.1 ENST00000579180.2 [Q96DH6-3] ENST00000674964.1 [Q96DH6-1] ENST00000675822.1 ENST00000675379.1 A0A6Q8PF05 ENST00000322684.7 [Q96DH6-2] A0A6Q8PFU8 A0A6Q8PH51 ENST00000442934.6 ENST00000676073.1 A0A6Q8PH41 J3KTC1 ENST00000674522.1 A0A6Q8PHT3 B4DHE8 Q96DH6 A0A6Q8PGF5 A0A6Q8PHP1 A0A6Q8PH26 ENST00000579590.5

MSI2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review