MAPRE2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	30% ± 11%	Explore
astrocyte	17 studies	37% ± 18%	Explore
oligodendrocyte	16 studies	50% ± 17%	Explore
CD8-positive, alpha-beta T cell	16 studies	28% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	38% ± 14%	Explore
pericyte	15 studies	22% ± 8%	Explore
endothelial cell	15 studies	30% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	30% ± 12%	Explore
T cell	13 studies	26% ± 9%	Explore
smooth muscle cell	13 studies	27% ± 6%	Explore
CD4-positive, alpha-beta T cell	13 studies	23% ± 6%	Explore
B cell	13 studies	25% ± 6%	Explore
mature NK T cell	12 studies	28% ± 9%	Explore
oligodendrocyte precursor cell	12 studies	38% ± 12%	Explore
regulatory T cell	12 studies	24% ± 7%	Explore
glutamatergic neuron	11 studies	57% ± 23%	Explore
naive B cell	11 studies	23% ± 6%	Explore
plasmacytoid dendritic cell	11 studies	31% ± 11%	Explore
gamma-delta T cell	11 studies	33% ± 7%	Explore
GABAergic neuron	10 studies	49% ± 23%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	22% ± 7%	Explore
microglial cell	10 studies	27% ± 10%	Explore
memory B cell	10 studies	21% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	27% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	23% ± 5%	Explore
neuron	8 studies	40% ± 16%	Explore
mucosal invariant T cell	8 studies	25% ± 4%	Explore
macrophage	7 studies	30% ± 11%	Explore
retinal ganglion cell	7 studies	47% ± 22%	Explore
hematopoietic stem cell	7 studies	25% ± 7%	Explore
fibroblast	7 studies	25% ± 8%	Explore
interneuron	6 studies	55% ± 23%	Explore
endothelial cell of lymphatic vessel	6 studies	22% ± 4%	Explore
amacrine cell	6 studies	34% ± 15%	Explore
retina horizontal cell	6 studies	35% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	25% ± 6%	Explore
glial cell	5 studies	30% ± 12%	Explore
pro-B cell	5 studies	26% ± 5%	Explore
cardiac muscle cell	5 studies	48% ± 9%	Explore
myeloid cell	5 studies	20% ± 3%	Explore
Mueller cell	5 studies	29% ± 10%	Explore
T follicular helper cell	5 studies	24% ± 4%	Explore
dendritic cell	5 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	23% ± 3%	Explore
platelet	5 studies	31% ± 12%	Explore
hematopoietic precursor cell	4 studies	22% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	21% ± 6%	Explore
leukocyte	4 studies	22% ± 4%	Explore
non-classical monocyte	4 studies	23% ± 6%	Explore
conventional dendritic cell	4 studies	23% ± 10%	Explore
retinal bipolar neuron	4 studies	32% ± 8%	Explore
granule cell	4 studies	36% ± 10%	Explore
immature B cell	4 studies	28% ± 5%	Explore
lymphocyte	4 studies	28% ± 9%	Explore
OFF-bipolar cell	4 studies	49% ± 15%	Explore
ON-bipolar cell	4 studies	42% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	23% ± 7%	Explore
innate lymphoid cell	4 studies	25% ± 8%	Explore
exhausted T cell	3 studies	29% ± 2%	Explore
GABAergic interneuron	3 studies	42% ± 2%	Explore
precursor B cell	3 studies	25% ± 6%	Explore
epithelial cell	3 studies	19% ± 2%	Explore
capillary endothelial cell	3 studies	26% ± 8%	Explore
retinal cone cell	3 studies	20% ± 0%	Explore
GABAergic amacrine cell	3 studies	42% ± 15%	Explore
glycinergic amacrine cell	3 studies	39% ± 11%	Explore
rod bipolar cell	3 studies	37% ± 8%	Explore
endothelial cell of vascular tree	3 studies	21% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
muscle cell	3 studies	33% ± 20%	Explore
abnormal cell	3 studies	28% ± 5%	Explore
megakaryocyte	3 studies	53% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 3%	Explore
Schwann cell	3 studies	29% ± 13%	Explore
goblet cell	3 studies	28% ± 10%	Explore
mast cell	3 studies	21% ± 1%	Explore
double negative thymocyte	3 studies	38% ± 8%	Explore
mural cell	3 studies	29% ± 16%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	17 studies	46% ± 20%	Explore
peripheral blood	9 studies	22% ± 4%	Explore
eye	5 studies	27% ± 8%	Explore
heart	4 studies	26% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	11899.94	2641 / 2642	100%	105.00	705 / 705
adrenal gland	100%	7997.78	258 / 258	99%	66.55	228 / 230
stomach	100%	2880.57	358 / 359	99%	30.46	282 / 286
intestine	100%	3804.05	966 / 966	98%	25.33	514 / 527
skin	97%	3348.84	1748 / 1809	99%	50.60	468 / 472
thymus	99%	3113.36	645 / 653	95%	26.86	573 / 605
lung	99%	4188.46	574 / 578	94%	23.90	1084 / 1155
breast	100%	3044.86	457 / 459	93%	23.12	1035 / 1118
kidney	87%	1918.63	77 / 89	98%	55.32	883 / 901
prostate	94%	2644.86	230 / 245	84%	16.29	421 / 502
liver	86%	1667.87	194 / 226	85%	17.45	347 / 406
bladder	100%	5092.00	21 / 21	71%	15.61	356 / 504
esophagus	75%	2737.45	1080 / 1445	96%	28.11	175 / 183
ovary	99%	3357.52	179 / 180	66%	9.95	285 / 430
uterus	98%	2559.16	167 / 170	60%	12.72	275 / 459
pancreas	50%	769.88	165 / 328	97%	29.33	173 / 178
blood vessel	100%	7877.40	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	50.42	29 / 29
spleen	100%	3599.22	241 / 241	0%	0	0 / 0
adipose	100%	3639.40	1201 / 1204	0%	0	0 / 0
muscle	98%	4589.77	788 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	27.25	78 / 80
heart	95%	7996.14	816 / 861	0%	0	0 / 0
peripheral blood	86%	2715.79	795 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	80%	13.40	36 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1