LENG8 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	16 studies	27% ± 12%	Explore
classical monocyte	15 studies	29% ± 13%	Explore
ciliated cell	14 studies	34% ± 13%	Explore
macrophage	12 studies	23% ± 9%	Explore
fibroblast	12 studies	22% ± 7%	Explore
B cell	11 studies	25% ± 7%	Explore
plasmacytoid dendritic cell	11 studies	27% ± 8%	Explore
pericyte	11 studies	22% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 10%	Explore
regulatory T cell	10 studies	18% ± 2%	Explore
T cell	9 studies	19% ± 4%	Explore
monocyte	9 studies	21% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	25% ± 14%	Explore
non-classical monocyte	9 studies	30% ± 17%	Explore
astrocyte	9 studies	26% ± 9%	Explore
type I pneumocyte	9 studies	26% ± 10%	Explore
adipocyte	9 studies	28% ± 6%	Explore
natural killer cell	8 studies	23% ± 8%	Explore
retinal rod cell	8 studies	48% ± 15%	Explore
memory B cell	8 studies	23% ± 16%	Explore
naive B cell	8 studies	24% ± 14%	Explore
myeloid cell	8 studies	25% ± 6%	Explore
endothelial cell of lymphatic vessel	8 studies	23% ± 9%	Explore
smooth muscle cell	8 studies	20% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	22% ± 6%	Explore
CD4-positive, alpha-beta T cell	7 studies	24% ± 9%	Explore
CD8-positive, alpha-beta T cell	7 studies	23% ± 9%	Explore
epithelial cell	7 studies	40% ± 16%	Explore
oligodendrocyte	7 studies	25% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	31% ± 17%	Explore
goblet cell	6 studies	30% ± 11%	Explore
microglial cell	6 studies	24% ± 10%	Explore
oligodendrocyte precursor cell	6 studies	23% ± 6%	Explore
dendritic cell	6 studies	28% ± 21%	Explore
mucosal invariant T cell	6 studies	18% ± 2%	Explore
type II pneumocyte	6 studies	22% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	27% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	26% ± 11%	Explore
mature NK T cell	5 studies	20% ± 5%	Explore
glutamatergic neuron	5 studies	32% ± 24%	Explore
lymphocyte	5 studies	22% ± 3%	Explore
mast cell	5 studies	23% ± 5%	Explore
basal cell	5 studies	29% ± 13%	Explore
retinal cone cell	5 studies	30% ± 5%	Explore
abnormal cell	5 studies	23% ± 3%	Explore
gamma-delta T cell	5 studies	19% ± 3%	Explore
conventional dendritic cell	4 studies	41% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	36% ± 9%	Explore
capillary endothelial cell	4 studies	19% ± 4%	Explore
neuron	4 studies	25% ± 11%	Explore
amacrine cell	4 studies	22% ± 1%	Explore
retinal bipolar neuron	4 studies	33% ± 7%	Explore
interneuron	4 studies	40% ± 18%	Explore
plasma cell	4 studies	24% ± 8%	Explore
retina horizontal cell	4 studies	24% ± 3%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
secretory cell	3 studies	18% ± 1%	Explore
hematopoietic precursor cell	3 studies	36% ± 12%	Explore
plasmablast	3 studies	39% ± 13%	Explore
granule cell	3 studies	20% ± 3%	Explore
hematopoietic stem cell	3 studies	30% ± 15%	Explore
precursor B cell	3 studies	18% ± 1%	Explore
retinal pigment epithelial cell	3 studies	26% ± 11%	Explore
Mueller cell	3 studies	23% ± 2%	Explore
rod bipolar cell	3 studies	32% ± 8%	Explore
connective tissue cell	3 studies	21% ± 4%	Explore
vein endothelial cell	3 studies	26% ± 13%	Explore
alveolar macrophage	3 studies	28% ± 13%	Explore
club cell	3 studies	24% ± 10%	Explore
myofibroblast cell	3 studies	32% ± 12%	Explore
respiratory goblet cell	3 studies	29% ± 10%	Explore
melanocyte	3 studies	32% ± 6%	Explore
GABAergic neuron	3 studies	33% ± 22%	Explore
hepatocyte	3 studies	36% ± 14%	Explore
immature B cell	3 studies	32% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 2%	Explore
mucus secreting cell	3 studies	28% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	12 studies	26% ± 16%	Explore
peripheral blood	10 studies	26% ± 11%	Explore
lung	9 studies	22% ± 7%	Explore
eye	8 studies	36% ± 12%	Explore
adipose	4 studies	25% ± 12%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	37815.67	1441 / 1445	100%	75.22	183 / 183
intestine	100%	49423.08	966 / 966	99%	77.30	522 / 527
prostate	100%	55381.16	245 / 245	99%	73.16	496 / 502
skin	100%	33847.04	1809 / 1809	99%	76.14	466 / 472
stomach	100%	34593.59	358 / 359	98%	71.75	281 / 286
bladder	100%	44858.52	21 / 21	98%	71.40	493 / 504
pancreas	100%	43379.59	328 / 328	98%	95.29	174 / 178
thymus	100%	65675.85	652 / 653	97%	88.39	589 / 605
breast	100%	45655.22	459 / 459	97%	58.84	1085 / 1118
uterus	100%	63619.59	170 / 170	97%	71.61	444 / 459
lung	100%	47566.88	578 / 578	97%	67.15	1115 / 1155
ovary	100%	65615.84	180 / 180	96%	76.58	413 / 430
adrenal gland	100%	32558.01	257 / 258	96%	57.18	221 / 230
kidney	100%	37277.07	89 / 89	93%	68.81	842 / 901
brain	93%	25776.23	2453 / 2642	99%	90.88	696 / 705
liver	96%	13048.09	217 / 226	79%	33.51	319 / 406
adipose	100%	37509.07	1204 / 1204	0%	0	0 / 0
spleen	100%	56321.57	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	58.16	1 / 1
blood vessel	100%	44662.66	1331 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	59.10	79 / 80
heart	98%	21113.89	847 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	48.92	43 / 45
peripheral blood	93%	19476.89	863 / 929	0%	0	0 / 0
muscle	88%	11988.24	703 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	73.92	24 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0