KANSL1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	46% ± 17%	Explore
natural killer cell	20 studies	29% ± 13%	Explore
fibroblast	18 studies	40% ± 19%	Explore
astrocyte	16 studies	50% ± 21%	Explore
CD8-positive, alpha-beta T cell	16 studies	29% ± 13%	Explore
pericyte	16 studies	37% ± 19%	Explore
macrophage	15 studies	45% ± 22%	Explore
B cell	14 studies	32% ± 12%	Explore
T cell	14 studies	31% ± 14%	Explore
smooth muscle cell	14 studies	36% ± 13%	Explore
oligodendrocyte	13 studies	48% ± 21%	Explore
microglial cell	13 studies	59% ± 19%	Explore
oligodendrocyte precursor cell	12 studies	49% ± 22%	Explore
CD4-positive, alpha-beta T cell	12 studies	31% ± 13%	Explore
mast cell	11 studies	31% ± 12%	Explore
glutamatergic neuron	10 studies	58% ± 24%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	31% ± 13%	Explore
epithelial cell	10 studies	44% ± 22%	Explore
basal cell	10 studies	39% ± 24%	Explore
adipocyte	10 studies	52% ± 15%	Explore
endothelial cell of lymphatic vessel	9 studies	43% ± 19%	Explore
GABAergic neuron	9 studies	55% ± 23%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	30% ± 13%	Explore
neuron	9 studies	48% ± 25%	Explore
ciliated cell	9 studies	32% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	26% ± 8%	Explore
naive B cell	8 studies	21% ± 2%	Explore
mature NK T cell	8 studies	30% ± 14%	Explore
amacrine cell	8 studies	44% ± 17%	Explore
myeloid cell	8 studies	41% ± 14%	Explore
endothelial cell of artery	8 studies	21% ± 6%	Explore
gamma-delta T cell	8 studies	28% ± 9%	Explore
regulatory T cell	8 studies	30% ± 11%	Explore
leukocyte	7 studies	48% ± 22%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	40% ± 11%	Explore
retinal ganglion cell	7 studies	48% ± 24%	Explore
retinal cone cell	7 studies	45% ± 15%	Explore
retinal rod cell	7 studies	40% ± 18%	Explore
capillary endothelial cell	7 studies	29% ± 14%	Explore
dendritic cell	7 studies	46% ± 14%	Explore
mesothelial cell	7 studies	45% ± 15%	Explore
mucosal invariant T cell	7 studies	26% ± 14%	Explore
memory B cell	7 studies	19% ± 4%	Explore
classical monocyte	6 studies	27% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	34% ± 12%	Explore
non-classical monocyte	6 studies	29% ± 15%	Explore
retina horizontal cell	6 studies	54% ± 17%	Explore
Mueller cell	6 studies	44% ± 22%	Explore
monocyte	6 studies	41% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	22% ± 4%	Explore
retinal bipolar neuron	5 studies	37% ± 17%	Explore
interneuron	5 studies	75% ± 17%	Explore
club cell	5 studies	49% ± 20%	Explore
cardiac muscle cell	5 studies	54% ± 14%	Explore
vein endothelial cell	5 studies	37% ± 21%	Explore
lymphocyte	5 studies	47% ± 24%	Explore
myofibroblast cell	5 studies	37% ± 18%	Explore
type I pneumocyte	5 studies	54% ± 13%	Explore
type II pneumocyte	5 studies	52% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	29% ± 11%	Explore
glial cell	4 studies	40% ± 13%	Explore
granule cell	4 studies	54% ± 4%	Explore
progenitor cell	4 studies	42% ± 15%	Explore
plasma cell	4 studies	44% ± 10%	Explore
OFF-bipolar cell	4 studies	50% ± 10%	Explore
ON-bipolar cell	4 studies	51% ± 11%	Explore
T follicular helper cell	4 studies	20% ± 4%	Explore
connective tissue cell	4 studies	28% ± 13%	Explore
plasmacytoid dendritic cell	4 studies	21% ± 2%	Explore
goblet cell	4 studies	36% ± 30%	Explore
transit amplifying cell	4 studies	36% ± 32%	Explore
cholangiocyte	3 studies	48% ± 21%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	56% ± 5%	Explore
endocardial cell	3 studies	37% ± 8%	Explore
mononuclear phagocyte	3 studies	36% ± 13%	Explore
GABAergic amacrine cell	3 studies	56% ± 11%	Explore
glycinergic amacrine cell	3 studies	52% ± 6%	Explore
rod bipolar cell	3 studies	52% ± 14%	Explore
CD4-positive helper T cell	3 studies	26% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	33% ± 12%	Explore
innate lymphoid cell	3 studies	37% ± 13%	Explore
endothelial cell of vascular tree	3 studies	48% ± 21%	Explore
hepatocyte	3 studies	65% ± 16%	Explore
retinal pigment epithelial cell	3 studies	52% ± 28%	Explore
alveolar macrophage	3 studies	55% ± 14%	Explore
respiratory goblet cell	3 studies	56% ± 19%	Explore
muscle cell	3 studies	46% ± 33%	Explore
brush cell	3 studies	34% ± 9%	Explore
T-helper 17 cell	3 studies	22% ± 2%	Explore
renal principal cell	3 studies	37% ± 17%	Explore
mucus secreting cell	3 studies	48% ± 6%	Explore
enteroendocrine cell	3 studies	24% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	55% ± 21%	Explore
lung	8 studies	36% ± 14%	Explore
eye	8 studies	48% ± 21%	Explore
peripheral blood	5 studies	36% ± 13%	Explore
heart	5 studies	45% ± 12%	Explore
intestine	5 studies	20% ± 3%	Explore
liver	4 studies	37% ± 21%	Explore
adipose	3 studies	50% ± 14%	Explore
kidney	3 studies	48% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4431.79	1445 / 1445	100%	12.48	183 / 183
stomach	100%	3179.84	359 / 359	100%	9.11	285 / 286
breast	100%	4706.78	459 / 459	100%	10.78	1113 / 1118
ovary	100%	5607.64	180 / 180	100%	7.93	428 / 430
lung	100%	4149.63	578 / 578	99%	9.76	1149 / 1155
intestine	100%	4386.10	966 / 966	99%	7.82	524 / 527
bladder	100%	4647.19	21 / 21	99%	8.17	500 / 504
thymus	100%	5282.38	653 / 653	99%	10.22	600 / 605
brain	99%	3077.47	2613 / 2642	100%	10.07	705 / 705
pancreas	100%	3032.22	328 / 328	99%	8.32	176 / 178
prostate	100%	4325.41	245 / 245	99%	8.13	495 / 502
uterus	100%	5763.95	170 / 170	98%	8.44	452 / 459
skin	100%	5161.81	1809 / 1809	98%	8.19	461 / 472
kidney	100%	2737.87	89 / 89	98%	7.80	880 / 901
adrenal gland	100%	3501.71	258 / 258	93%	5.46	214 / 230
liver	100%	1733.06	226 / 226	77%	3.73	313 / 406
adipose	100%	4181.72	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4166.05	1335 / 1335	0%	0	0 / 0
muscle	100%	2905.81	803 / 803	0%	0	0 / 0
spleen	100%	4715.90	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.41	1 / 1
heart	99%	2013.01	850 / 861	0%	0	0 / 0
peripheral blood	97%	3054.37	905 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	5.95	28 / 29
tonsil	0%	0	0 / 0	96%	7.92	43 / 45
eye	0%	0	0 / 0	91%	5.67	73 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006325	Biological process	chromatin organization
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_1903108	Biological process	regulation of mitochondrial transcription
GO_0000776	Cellular component	kinetochore
GO_0005654	Cellular component	nucleoplasm
GO_0044545	Cellular component	NSL complex
GO_0071339	Cellular component	MLL1 complex
GO_0000123	Cellular component	histone acetyltransferase complex
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0035035	Molecular function	histone acetyltransferase binding

IV. Literature review

[source]

Gene name	KANSL1
Protein name	KAT8 regulatory NSL complex subunit 1 (MLL1/MLL complex subunit KANSL1) (MSL1 homolog 1) (hMSL1v1) (NSL complex protein NSL1) (Non-specific lethal 1 homolog) KAT8 regulatory NSL complex subunit 1
Synonyms	NSL1 CENP-36 KIAA1267 MSL1V1
Description	FUNCTION: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. .
Accessions	ENST00000611596.1 A0A0G2JNT7 ENST00000572904.6 [Q7Z3B3-1] ENST00000627698.2 ENST00000574590.6 ENST00000610328.2 A0A0G2JQF5 ENST00000639150.1 ENST00000626533.2 ENST00000632215.1 I3L243 ENST00000633448.1 A0A1W2PRA9 ENST00000613150.3 ENST00000630200.2 ENST00000432791.7 [Q7Z3B3-1] A0A1W2PPV8 A0A1W2PRB5 ENST00000639467.1 A0A3B3IT55 ENST00000262419.10 [Q7Z3B3-1] ENST00000638275.1 ENST00000633346.1 A0A1W2PRR3 ENST00000629551.2 ENST00000633819.1 ENST00000622036.4 ENST00000639853.1 ENST00000639531.1 A0A0G2JNB1 A0A1W2PS83 ENST00000629079.1 ENST00000576739.2 Q7Z3B3 ENST00000633540.1 A0A0G2JQP8 ENST00000648792.1 ENST00000575318.6 ENST00000640636.1 ENST00000628726.1 A0A0G2JQF4 A0A1W2PQT4 I3L233 A0A0J9YVS1 A0A9S7M8F4 ENST00000571698.2 ENST00000626557.2 A0A0G2JRW7

KANSL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review