IRF2BP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	29 studies	28% ± 10%	Explore
fibroblast	28 studies	23% ± 7%	Explore
macrophage	27 studies	29% ± 10%	Explore
classical monocyte	25 studies	37% ± 19%	Explore
plasmacytoid dendritic cell	21 studies	53% ± 18%	Explore
conventional dendritic cell	20 studies	32% ± 22%	Explore
smooth muscle cell	18 studies	29% ± 9%	Explore
monocyte	17 studies	29% ± 11%	Explore
basal cell	17 studies	33% ± 14%	Explore
pericyte	16 studies	26% ± 10%	Explore
ciliated cell	14 studies	34% ± 18%	Explore
B cell	12 studies	23% ± 5%	Explore
dendritic cell	12 studies	31% ± 19%	Explore
non-classical monocyte	12 studies	28% ± 13%	Explore
epithelial cell	12 studies	43% ± 19%	Explore
T cell	11 studies	24% ± 8%	Explore
endothelial cell of lymphatic vessel	11 studies	27% ± 9%	Explore
secretory cell	11 studies	25% ± 9%	Explore
CD4-positive, alpha-beta T cell	11 studies	27% ± 11%	Explore
regulatory T cell	11 studies	22% ± 7%	Explore
natural killer cell	10 studies	21% ± 5%	Explore
CD8-positive, alpha-beta T cell	10 studies	22% ± 6%	Explore
oligodendrocyte	10 studies	21% ± 7%	Explore
gamma-delta T cell	10 studies	26% ± 10%	Explore
myeloid cell	10 studies	37% ± 19%	Explore
mast cell	9 studies	29% ± 6%	Explore
type II pneumocyte	9 studies	29% ± 13%	Explore
naive B cell	9 studies	26% ± 9%	Explore
abnormal cell	9 studies	26% ± 9%	Explore
vein endothelial cell	9 studies	24% ± 8%	Explore
memory B cell	9 studies	26% ± 12%	Explore
leukocyte	8 studies	27% ± 7%	Explore
connective tissue cell	8 studies	23% ± 7%	Explore
astrocyte	8 studies	23% ± 7%	Explore
endothelial cell of artery	8 studies	28% ± 6%	Explore
goblet cell	8 studies	25% ± 9%	Explore
endothelial cell of vascular tree	8 studies	24% ± 7%	Explore
capillary endothelial cell	7 studies	24% ± 3%	Explore
myofibroblast cell	7 studies	25% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	33% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	36% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	34% ± 20%	Explore
progenitor cell	6 studies	29% ± 7%	Explore
mucosal invariant T cell	6 studies	24% ± 7%	Explore
T follicular helper cell	6 studies	28% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	36% ± 18%	Explore
type I pneumocyte	5 studies	36% ± 6%	Explore
mononuclear phagocyte	5 studies	31% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	32% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	38% ± 14%	Explore
hematopoietic precursor cell	5 studies	58% ± 20%	Explore
mature NK T cell	5 studies	21% ± 3%	Explore
enteroendocrine cell	5 studies	35% ± 10%	Explore
intestinal crypt stem cell	5 studies	34% ± 10%	Explore
transit amplifying cell	5 studies	20% ± 4%	Explore
hematopoietic stem cell	5 studies	38% ± 26%	Explore
club cell	5 studies	33% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	23% ± 4%	Explore
kidney loop of Henle epithelial cell	4 studies	23% ± 7%	Explore
neuron	4 studies	27% ± 9%	Explore
neutrophil	4 studies	24% ± 6%	Explore
brush cell	4 studies	24% ± 11%	Explore
Mueller cell	4 studies	27% ± 5%	Explore
innate lymphoid cell	4 studies	27% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	22% ± 2%	Explore
GABAergic neuron	4 studies	26% ± 3%	Explore
immature B cell	4 studies	24% ± 14%	Explore
duct epithelial cell	3 studies	19% ± 2%	Explore
pancreatic A cell	3 studies	47% ± 24%	Explore
type B pancreatic cell	3 studies	47% ± 25%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
glomerular endothelial cell	3 studies	21% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 6%	Explore
enterocyte	3 studies	19% ± 1%	Explore
common myeloid progenitor	3 studies	29% ± 13%	Explore
lymphocyte	3 studies	32% ± 12%	Explore
precursor B cell	3 studies	37% ± 19%	Explore
amacrine cell	3 studies	19% ± 5%	Explore
retina horizontal cell	3 studies	21% ± 4%	Explore
serous secreting cell	3 studies	21% ± 1%	Explore
respiratory goblet cell	3 studies	25% ± 10%	Explore
acinar cell	3 studies	43% ± 18%	Explore
intermediate monocyte	3 studies	44% ± 26%	Explore
CD4-positive helper T cell	3 studies	32% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	38% ± 14%	Explore
luminal cell of prostate epithelium	3 studies	29% ± 3%	Explore
glutamatergic neuron	3 studies	29% ± 7%	Explore
pancreatic ductal cell	3 studies	46% ± 23%	Explore
oligodendrocyte precursor cell	3 studies	29% ± 3%	Explore
granulocyte	3 studies	28% ± 14%	Explore
granulocyte monocyte progenitor cell	3 studies	40% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	59% ± 22%	Explore
glial cell	3 studies	23% ± 7%	Explore
alveolar macrophage	3 studies	20% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 11%	Explore
T-helper 17 cell	3 studies	21% ± 5%	Explore
interneuron	3 studies	30% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	21% ± 4%	Explore
hepatocyte	3 studies	41% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	27% ± 11%	Explore
peripheral blood	10 studies	32% ± 15%	Explore
intestine	8 studies	23% ± 8%	Explore
brain	6 studies	28% ± 7%	Explore
uterus	5 studies	30% ± 13%	Explore
bone marrow	4 studies	33% ± 22%	Explore
eye	4 studies	18% ± 2%	Explore
breast	4 studies	21% ± 4%	Explore
pancreas	3 studies	46% ± 23%	Explore
kidney	3 studies	22% ± 0%	Explore
lymph node	3 studies	21% ± 1%	Explore
prostate	3 studies	35% ± 8%	Explore
liver	3 studies	28% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	8044.55	459 / 459	100%	148.97	1118 / 1118
esophagus	100%	7370.77	1445 / 1445	100%	144.89	183 / 183
intestine	100%	7597.57	966 / 966	100%	135.75	527 / 527
ovary	100%	9461.72	180 / 180	100%	159.41	430 / 430
prostate	100%	7182.61	245 / 245	100%	80.70	502 / 502
stomach	100%	5927.32	359 / 359	100%	143.08	286 / 286
uterus	100%	7801.72	170 / 170	100%	108.01	459 / 459
thymus	100%	7784.47	653 / 653	100%	124.79	604 / 605
lung	100%	6440.80	576 / 578	100%	104.21	1154 / 1155
liver	100%	4707.78	226 / 226	100%	88.61	404 / 406
brain	99%	4086.05	2623 / 2642	100%	77.99	705 / 705
kidney	100%	4565.17	89 / 89	99%	89.23	888 / 901
pancreas	100%	3870.34	328 / 328	98%	89.24	175 / 178
bladder	100%	6449.19	21 / 21	98%	89.73	493 / 504
skin	100%	9406.77	1809 / 1809	97%	71.28	460 / 472
adrenal gland	100%	4461.02	258 / 258	95%	61.42	219 / 230
adipose	100%	6357.41	1204 / 1204	0%	0	0 / 0
blood vessel	100%	11057.45	1335 / 1335	0%	0	0 / 0
spleen	100%	4344.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	80.74	45 / 45
ureter	0%	0	0 / 0	100%	39.88	1 / 1
muscle	99%	4946.17	795 / 803	0%	0	0 / 0
heart	98%	4956.11	847 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	47.11	76 / 80
lymph node	0%	0	0 / 0	86%	42.18	25 / 29
peripheral blood	84%	3407.41	782 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	IRF2BP2
Protein name	Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)
Synonyms
Description	FUNCTION: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities . Represses the NFAT1-dependent transactivation of NFAT-responsive promoters . Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles . Plays a role in immature B-cell differentiation . .
Accessions	Q7Z5L9 ENST00000366609.4 [Q7Z5L9-1] ENST00000366610.7 [Q7Z5L9-2]

GO_0002327	Biological process	immature B cell differentiation
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003714	Molecular function	transcription corepressor activity
GO_0046872	Molecular function	metal ion binding

IRF2BP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review