H1-4 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	18 studies	39% ± 18%	Explore
B cell	17 studies	30% ± 11%	Explore
CD8-positive, alpha-beta T cell	16 studies	31% ± 12%	Explore
CD4-positive, alpha-beta T cell	13 studies	33% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	38% ± 14%	Explore
conventional dendritic cell	12 studies	32% ± 15%	Explore
regulatory T cell	12 studies	28% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	35% ± 13%	Explore
classical monocyte	11 studies	30% ± 13%	Explore
memory B cell	11 studies	27% ± 9%	Explore
T cell	10 studies	31% ± 18%	Explore
plasmacytoid dendritic cell	10 studies	33% ± 14%	Explore
non-classical monocyte	10 studies	26% ± 10%	Explore
gamma-delta T cell	10 studies	37% ± 13%	Explore
naive B cell	9 studies	30% ± 7%	Explore
mucosal invariant T cell	9 studies	33% ± 14%	Explore
dendritic cell	8 studies	35% ± 15%	Explore
mature NK T cell	8 studies	31% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	25% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	26% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	25% ± 6%	Explore
plasma cell	7 studies	35% ± 12%	Explore
plasmablast	7 studies	61% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	38% ± 7%	Explore
monocyte	6 studies	34% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	42% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	34% ± 15%	Explore
macrophage	5 studies	27% ± 16%	Explore
precursor B cell	5 studies	32% ± 6%	Explore
mast cell	4 studies	38% ± 19%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	31% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	28% ± 12%	Explore
hematopoietic precursor cell	4 studies	39% ± 10%	Explore
epithelial cell	4 studies	23% ± 9%	Explore
exhausted T cell	4 studies	30% ± 15%	Explore
hematopoietic stem cell	4 studies	41% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	28% ± 9%	Explore
erythrocyte	4 studies	49% ± 20%	Explore
endothelial cell	3 studies	24% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	23% ± 9%	Explore
pro-B cell	3 studies	27% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	42% ± 11%	Explore
intermediate monocyte	3 studies	23% ± 4%	Explore
double negative thymocyte	3 studies	38% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	32% ± 10%	Explore
bone marrow	3 studies	19% ± 1%	Explore
lymph node	3 studies	17% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	95%	90.13	233 / 245	93%	10.70	468 / 502
ovary	78%	55.52	140 / 180	99%	11.17	426 / 430
bladder	90%	30.76	19 / 21	71%	30.91	357 / 504
esophagus	60%	22.09	862 / 1445	97%	9.74	178 / 183
breast	91%	88.47	416 / 459	64%	10.01	712 / 1118
lung	76%	37.74	439 / 578	71%	11.46	817 / 1155
uterus	65%	26.62	110 / 170	81%	6.48	373 / 459
intestine	76%	55.31	736 / 966	61%	13.64	323 / 527
stomach	54%	31.62	195 / 359	76%	22.17	218 / 286
pancreas	54%	23.69	176 / 328	62%	8.30	111 / 178
skin	76%	63.98	1374 / 1809	37%	0.84	174 / 472
thymus	73%	29.69	475 / 653	40%	1.37	239 / 605
kidney	78%	35.38	69 / 89	17%	2.81	154 / 901
lymph node	0%	0	0 / 0	90%	4.23	26 / 29
liver	53%	19.93	119 / 226	33%	0.97	135 / 406
adipose	83%	54.95	1003 / 1204	0%	0	0 / 0
peripheral blood	83%	134.12	767 / 929	0%	0	0 / 0
brain	54%	15.00	1432 / 2642	28%	1.88	194 / 705
tonsil	0%	0	0 / 0	76%	2.40	34 / 45
spleen	74%	42.49	179 / 241	0%	0	0 / 0
blood vessel	62%	24.03	829 / 1335	0%	0	0 / 0
adrenal gland	30%	6.99	78 / 258	20%	0.48	45 / 230
heart	33%	8.53	282 / 861	0%	0	0 / 0
muscle	30%	7.37	243 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	8%	0.09	6 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1