CPNE3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	20 studies	24% ± 10%	Explore
conventional dendritic cell	18 studies	31% ± 12%	Explore
plasmacytoid dendritic cell	17 studies	33% ± 10%	Explore
natural killer cell	16 studies	19% ± 3%	Explore
endothelial cell	15 studies	27% ± 9%	Explore
ciliated cell	12 studies	30% ± 14%	Explore
endothelial cell of lymphatic vessel	11 studies	25% ± 8%	Explore
smooth muscle cell	11 studies	22% ± 6%	Explore
basal cell	11 studies	32% ± 14%	Explore
B cell	10 studies	18% ± 2%	Explore
type I pneumocyte	10 studies	25% ± 8%	Explore
epithelial cell	10 studies	34% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	21% ± 4%	Explore
pericyte	9 studies	21% ± 5%	Explore
gamma-delta T cell	9 studies	21% ± 8%	Explore
type II pneumocyte	8 studies	24% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	21% ± 3%	Explore
classical monocyte	8 studies	20% ± 6%	Explore
mucosal invariant T cell	8 studies	19% ± 4%	Explore
dendritic cell	7 studies	43% ± 25%	Explore
abnormal cell	7 studies	24% ± 5%	Explore
CD8-positive, alpha-beta T cell	7 studies	19% ± 3%	Explore
astrocyte	7 studies	29% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 4%	Explore
secretory cell	6 studies	27% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
non-classical monocyte	6 studies	25% ± 9%	Explore
CD4-positive, alpha-beta T cell	6 studies	19% ± 4%	Explore
mature NK T cell	6 studies	17% ± 1%	Explore
neuron	6 studies	37% ± 15%	Explore
oligodendrocyte precursor cell	6 studies	31% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
kidney loop of Henle epithelial cell	5 studies	25% ± 5%	Explore
connective tissue cell	5 studies	22% ± 6%	Explore
naive B cell	5 studies	18% ± 3%	Explore
myofibroblast cell	5 studies	23% ± 3%	Explore
endothelial cell of vascular tree	5 studies	21% ± 5%	Explore
memory B cell	5 studies	18% ± 2%	Explore
endothelial cell of artery	5 studies	17% ± 2%	Explore
glutamatergic neuron	5 studies	40% ± 19%	Explore
oligodendrocyte	5 studies	20% ± 4%	Explore
club cell	4 studies	27% ± 10%	Explore
respiratory goblet cell	4 studies	24% ± 8%	Explore
pancreatic A cell	4 studies	54% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
myeloid cell	4 studies	30% ± 10%	Explore
regulatory T cell	4 studies	20% ± 2%	Explore
GABAergic neuron	4 studies	40% ± 12%	Explore
goblet cell	4 studies	21% ± 3%	Explore
T cell	3 studies	17% ± 1%	Explore
hematopoietic precursor cell	3 studies	23% ± 9%	Explore
type B pancreatic cell	3 studies	47% ± 18%	Explore
squamous epithelial cell	3 studies	38% ± 18%	Explore
retina horizontal cell	3 studies	23% ± 4%	Explore
cardiac muscle cell	3 studies	18% ± 3%	Explore
Mueller cell	3 studies	26% ± 5%	Explore
germinal center B cell	3 studies	28% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 2%	Explore
mesothelial cell	3 studies	27% ± 15%	Explore
macrophage	3 studies	21% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
intestinal crypt stem cell	3 studies	23% ± 3%	Explore
vein endothelial cell	3 studies	17% ± 1%	Explore
hematopoietic stem cell	3 studies	18% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	27% ± 7%	Explore
interneuron	3 studies	37% ± 18%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	20% ± 5%	Explore
lung	9 studies	25% ± 13%	Explore
brain	6 studies	33% ± 11%	Explore
pancreas	3 studies	55% ± 15%	Explore
uterus	3 studies	31% ± 13%	Explore
kidney	3 studies	18% ± 2%	Explore
breast	3 studies	16% ± 0%	Explore
intestine	3 studies	23% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6718.96	1445 / 1445	100%	79.78	183 / 183
ovary	100%	4746.86	180 / 180	100%	52.99	430 / 430
breast	100%	5169.66	459 / 459	100%	122.37	1117 / 1118
prostate	100%	4613.08	245 / 245	100%	92.82	501 / 502
lung	100%	4118.22	577 / 578	100%	70.97	1153 / 1155
intestine	100%	4173.64	966 / 966	99%	59.96	524 / 527
stomach	100%	3531.83	359 / 359	99%	67.44	284 / 286
thymus	100%	5782.98	653 / 653	99%	50.44	599 / 605
brain	99%	2556.28	2623 / 2642	100%	69.69	703 / 705
uterus	100%	5019.26	170 / 170	99%	51.16	454 / 459
bladder	100%	4660.05	21 / 21	99%	63.27	498 / 504
pancreas	99%	2964.38	326 / 328	99%	45.97	176 / 178
kidney	100%	3508.39	89 / 89	97%	55.97	878 / 901
liver	100%	2390.74	226 / 226	96%	36.49	389 / 406
adrenal gland	100%	4543.60	258 / 258	95%	48.26	219 / 230
skin	100%	6261.24	1809 / 1809	94%	54.06	444 / 472
adipose	100%	5099.63	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5833.61	1335 / 1335	0%	0	0 / 0
spleen	100%	2927.86	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	65.86	45 / 45
ureter	0%	0	0 / 0	100%	40.35	1 / 1
muscle	99%	2055.22	792 / 803	0%	0	0 / 0
heart	96%	3644.14	826 / 861	0%	0	0 / 0
peripheral blood	93%	3675.25	868 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	39.31	27 / 29
eye	0%	0	0 / 0	84%	37.03	67 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0