CHD9 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	47 studies	40% ± 17%	Explore
fibroblast	41 studies	41% ± 18%	Explore
B cell	32 studies	29% ± 12%	Explore
natural killer cell	30 studies	23% ± 6%	Explore
pericyte	30 studies	41% ± 16%	Explore
macrophage	29 studies	32% ± 18%	Explore
smooth muscle cell	28 studies	33% ± 15%	Explore
astrocyte	22 studies	61% ± 19%	Explore
mast cell	20 studies	27% ± 12%	Explore
memory B cell	18 studies	21% ± 3%	Explore
plasmacytoid dendritic cell	18 studies	43% ± 13%	Explore
naive B cell	18 studies	23% ± 4%	Explore
microglial cell	18 studies	62% ± 17%	Explore
endothelial cell of lymphatic vessel	17 studies	39% ± 17%	Explore
basal cell	17 studies	40% ± 19%	Explore
oligodendrocyte precursor cell	17 studies	64% ± 18%	Explore
oligodendrocyte	16 studies	48% ± 15%	Explore
epithelial cell	16 studies	38% ± 22%	Explore
ciliated cell	15 studies	36% ± 13%	Explore
capillary endothelial cell	15 studies	28% ± 8%	Explore
myofibroblast cell	14 studies	37% ± 11%	Explore
connective tissue cell	14 studies	35% ± 13%	Explore
glutamatergic neuron	13 studies	63% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	29% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	23% ± 7%	Explore
conventional dendritic cell	13 studies	25% ± 14%	Explore
vein endothelial cell	13 studies	32% ± 17%	Explore
endothelial cell of vascular tree	12 studies	29% ± 16%	Explore
GABAergic neuron	11 studies	67% ± 20%	Explore
endothelial cell of artery	11 studies	29% ± 11%	Explore
mesothelial cell	11 studies	43% ± 14%	Explore
mucosal invariant T cell	11 studies	21% ± 4%	Explore
adipocyte	11 studies	66% ± 19%	Explore
T cell	10 studies	26% ± 11%	Explore
type I pneumocyte	10 studies	42% ± 13%	Explore
non-classical monocyte	10 studies	26% ± 11%	Explore
neuron	10 studies	56% ± 19%	Explore
myeloid cell	10 studies	40% ± 15%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 4%	Explore
retinal cone cell	9 studies	74% ± 18%	Explore
retinal rod cell	9 studies	71% ± 14%	Explore
dendritic cell	9 studies	42% ± 18%	Explore
plasma cell	8 studies	32% ± 14%	Explore
progenitor cell	8 studies	36% ± 14%	Explore
goblet cell	8 studies	33% ± 23%	Explore
amacrine cell	8 studies	62% ± 12%	Explore
monocyte	8 studies	38% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	24% ± 7%	Explore
interneuron	7 studies	71% ± 18%	Explore
retinal ganglion cell	7 studies	61% ± 18%	Explore
club cell	7 studies	41% ± 14%	Explore
type II pneumocyte	7 studies	44% ± 12%	Explore
alveolar macrophage	6 studies	41% ± 23%	Explore
respiratory goblet cell	6 studies	42% ± 18%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 4%	Explore
mature NK T cell	6 studies	22% ± 7%	Explore
abnormal cell	6 studies	37% ± 14%	Explore
leukocyte	6 studies	40% ± 21%	Explore
glial cell	6 studies	44% ± 19%	Explore
precursor B cell	6 studies	32% ± 10%	Explore
retina horizontal cell	6 studies	60% ± 8%	Explore
Mueller cell	6 studies	63% ± 12%	Explore
hematopoietic precursor cell	5 studies	39% ± 21%	Explore
secretory cell	5 studies	30% ± 6%	Explore
classical monocyte	5 studies	25% ± 10%	Explore
hepatocyte	5 studies	57% ± 23%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	36% ± 18%	Explore
retinal bipolar neuron	5 studies	62% ± 8%	Explore
OFF-bipolar cell	5 studies	56% ± 18%	Explore
ON-bipolar cell	5 studies	46% ± 18%	Explore
kidney loop of Henle epithelial cell	5 studies	40% ± 20%	Explore
pro-B cell	5 studies	35% ± 9%	Explore
brush cell	5 studies	36% ± 7%	Explore
adventitial cell	5 studies	30% ± 13%	Explore
cardiac muscle cell	5 studies	58% ± 14%	Explore
innate lymphoid cell	5 studies	22% ± 3%	Explore
hematopoietic stem cell	5 studies	31% ± 8%	Explore
gamma-delta T cell	5 studies	28% ± 14%	Explore
pancreatic A cell	4 studies	43% ± 19%	Explore
podocyte	4 studies	42% ± 14%	Explore
epithelial cell of proximal tubule	4 studies	40% ± 25%	Explore
renal alpha-intercalated cell	4 studies	37% ± 12%	Explore
granule cell	4 studies	57% ± 6%	Explore
glycinergic amacrine cell	4 studies	47% ± 19%	Explore
immature B cell	4 studies	29% ± 2%	Explore
retinal pigment epithelial cell	4 studies	53% ± 21%	Explore
mononuclear phagocyte	4 studies	34% ± 15%	Explore
lymphocyte	4 studies	41% ± 9%	Explore
muscle cell	4 studies	45% ± 22%	Explore
enteroendocrine cell	4 studies	29% ± 14%	Explore
mucus secreting cell	4 studies	44% ± 16%	Explore
myoepithelial cell	4 studies	37% ± 19%	Explore
renal principal cell	4 studies	37% ± 12%	Explore
ionocyte	3 studies	33% ± 5%	Explore
pancreatic D cell	3 studies	45% ± 27%	Explore
type B pancreatic cell	3 studies	52% ± 22%	Explore
cholangiocyte	3 studies	47% ± 19%	Explore
hepatic stellate cell	3 studies	51% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
plasmablast	3 studies	47% ± 19%	Explore
glomerular endothelial cell	3 studies	36% ± 6%	Explore
renal beta-intercalated cell	3 studies	44% ± 11%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	63% ± 3%	Explore
neural crest cell	3 studies	50% ± 5%	Explore
GABAergic interneuron	3 studies	66% ± 3%	Explore
squamous epithelial cell	3 studies	37% ± 23%	Explore
endocardial cell	3 studies	53% ± 9%	Explore
tissue-resident macrophage	3 studies	27% ± 12%	Explore
GABAergic amacrine cell	3 studies	66% ± 5%	Explore
rod bipolar cell	3 studies	62% ± 6%	Explore
neural progenitor cell	3 studies	63% ± 15%	Explore
ependymal cell	3 studies	56% ± 10%	Explore
intestinal crypt stem cell	3 studies	18% ± 1%	Explore
chondrocyte	3 studies	56% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 8%	Explore
Schwann cell	3 studies	41% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	20 studies	57% ± 19%	Explore
lung	15 studies	34% ± 13%	Explore
eye	10 studies	64% ± 17%	Explore
kidney	7 studies	36% ± 18%	Explore
intestine	7 studies	29% ± 14%	Explore
heart	6 studies	48% ± 17%	Explore
peripheral blood	4 studies	32% ± 16%	Explore
uterus	4 studies	27% ± 12%	Explore
liver	4 studies	46% ± 14%	Explore
adipose	4 studies	51% ± 27%	Explore
pancreas	3 studies	48% ± 17%	Explore
lymph node	3 studies	18% ± 2%	Explore
breast	3 studies	30% ± 7%	Explore
bone marrow	3 studies	26% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3723.94	1445 / 1445	100%	17.44	183 / 183
lung	100%	4053.28	576 / 578	100%	10.25	1152 / 1155
breast	100%	5303.68	459 / 459	99%	12.24	1109 / 1118
thymus	100%	4482.19	653 / 653	99%	12.86	600 / 605
brain	99%	2706.20	2616 / 2642	100%	19.72	705 / 705
pancreas	99%	2031.04	326 / 328	99%	10.53	176 / 178
kidney	100%	2647.09	89 / 89	98%	13.44	885 / 901
ovary	100%	4368.59	180 / 180	98%	6.33	422 / 430
prostate	100%	4054.85	245 / 245	98%	9.92	492 / 502
uterus	100%	4490.20	170 / 170	98%	9.23	449 / 459
adrenal gland	100%	3655.39	258 / 258	97%	9.60	224 / 230
stomach	100%	2747.01	359 / 359	97%	9.02	278 / 286
bladder	100%	4186.95	21 / 21	96%	7.61	484 / 504
intestine	100%	3984.32	966 / 966	95%	7.79	503 / 527
skin	100%	5372.00	1809 / 1809	93%	11.26	437 / 472
liver	99%	1795.25	224 / 226	76%	3.87	309 / 406
adipose	100%	5204.15	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4280.73	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	6.22	29 / 29
muscle	100%	3512.26	803 / 803	0%	0	0 / 0
spleen	100%	2878.11	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.60	1 / 1
heart	98%	2421.16	844 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	9.33	44 / 45
eye	0%	0	0 / 0	74%	5.96	59 / 80
peripheral blood	40%	1550.64	371 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	CHD9
Protein name	Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) CHD9 protein Chromodomain helicase DNA binding protein 9 DNA helicase (EC 3.6.4.12)
Synonyms	KIAA0308 AD-013 x0008 PRIC320 KISH2
Description	FUNCTION: Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity). .
Accessions	H3BV31 Q8N4Q2 H3BTW3 ENST00000566029.5 [Q3L8U1-2] ENST00000562785.1 J3KSW5 Q3L8U1 ENST00000565442.1 B7ZML1 H3BSP3 H3BRU9 ENST00000564600.6 I3L340 ENST00000398510.7 [Q3L8U1-1] J3KRH9 ENST00000615216.4 ENST00000565803.2 ENST00000563410.1 ENST00000565832.5 A0A087WU44 ENST00000564641.1 ENST00000447540.6 [Q3L8U1-1] ENST00000564845.5 [Q3L8U1-2]

GO_0006338	Biological process	chromatin remodeling
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0003677	Molecular function	DNA binding
GO_0140658	Molecular function	ATP-dependent chromatin remodeler activity
GO_0004386	Molecular function	helicase activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0005524	Molecular function	ATP binding

CHD9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review