ARHGAP15 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0008360Biological processregulation of cell shape
GO_0043087Biological processregulation of GTPase activity
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameARHGAP15
Protein nameRho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)
Rho GTPase activating protein 15
SynonymsBM-046
BM-024
BM-030
DescriptionFUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. .

AccessionsB8ZZK0
ENST00000409869.5
Q53QZ3
ENST00000295095.11