APBB1IP report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	35 studies	31% ± 10%	Explore
natural killer cell	34 studies	32% ± 10%	Explore
CD8-positive, alpha-beta T cell	34 studies	31% ± 11%	Explore
macrophage	28 studies	32% ± 12%	Explore
CD4-positive, alpha-beta T cell	28 studies	30% ± 9%	Explore
T cell	26 studies	35% ± 12%	Explore
regulatory T cell	26 studies	38% ± 11%	Explore
non-classical monocyte	22 studies	37% ± 11%	Explore
monocyte	20 studies	33% ± 14%	Explore
classical monocyte	20 studies	31% ± 12%	Explore
mature NK T cell	19 studies	31% ± 9%	Explore
conventional dendritic cell	18 studies	29% ± 15%	Explore
memory B cell	18 studies	28% ± 8%	Explore
gamma-delta T cell	17 studies	36% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	29% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	28% ± 9%	Explore
plasmacytoid dendritic cell	16 studies	47% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	36% ± 9%	Explore
naive B cell	15 studies	26% ± 6%	Explore
microglial cell	15 studies	72% ± 16%	Explore
mucosal invariant T cell	14 studies	32% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	32% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	36% ± 12%	Explore
dendritic cell	12 studies	38% ± 13%	Explore
myeloid cell	12 studies	36% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	31% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	37% ± 7%	Explore
adipocyte	10 studies	50% ± 13%	Explore
leukocyte	7 studies	50% ± 24%	Explore
T follicular helper cell	7 studies	31% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	37% ± 11%	Explore
neutrophil	6 studies	29% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	36% ± 10%	Explore
precursor B cell	6 studies	49% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	34% ± 6%	Explore
alveolar macrophage	5 studies	35% ± 15%	Explore
hematopoietic precursor cell	5 studies	28% ± 8%	Explore
exhausted T cell	5 studies	37% ± 8%	Explore
mononuclear phagocyte	5 studies	32% ± 11%	Explore
lymphocyte	5 studies	44% ± 15%	Explore
pro-B cell	5 studies	57% ± 17%	Explore
CD4-positive helper T cell	4 studies	27% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	25% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	26% ± 8%	Explore
immature B cell	4 studies	38% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	37% ± 13%	Explore
innate lymphoid cell	4 studies	30% ± 10%	Explore
double negative thymocyte	4 studies	44% ± 11%	Explore
plasmablast	3 studies	38% ± 16%	Explore
germinal center B cell	3 studies	24% ± 6%	Explore
hepatocyte	3 studies	47% ± 27%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 10%	Explore
T-helper 17 cell	3 studies	26% ± 5%	Explore
T-helper 1 cell	3 studies	31% ± 10%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	35% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	31% ± 10%	Explore
lung	7 studies	19% ± 3%	Explore
bone marrow	4 studies	23% ± 6%	Explore
lymph node	4 studies	30% ± 4%	Explore
adipose	4 studies	32% ± 8%	Explore
liver	3 studies	30% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	95%	1896.44	435 / 459	88%	15.47	985 / 1118
lung	99%	2015.35	574 / 578	81%	13.94	937 / 1155
liver	100%	2618.37	225 / 226	80%	20.95	323 / 406
bladder	95%	924.71	20 / 21	48%	10.74	243 / 504
kidney	49%	540.26	44 / 89	89%	48.82	802 / 901
brain	40%	372.26	1060 / 2642	94%	31.93	662 / 705
stomach	68%	492.62	243 / 359	64%	13.25	183 / 286
skin	56%	596.16	1021 / 1809	64%	13.77	300 / 472
esophagus	59%	441.75	854 / 1445	61%	10.67	111 / 183
intestine	71%	899.90	683 / 966	45%	7.74	236 / 527
lymph node	0%	0	0 / 0	100%	100.37	29 / 29
peripheral blood	100%	18181.94	929 / 929	0%	0	0 / 0
spleen	100%	7374.65	241 / 241	0%	0	0 / 0
adipose	100%	3097.92	1203 / 1204	0%	0	0 / 0
thymus	45%	375.38	296 / 653	54%	34.64	325 / 605
pancreas	20%	136.52	67 / 328	78%	12.70	138 / 178
adrenal gland	74%	551.33	192 / 258	20%	1.89	45 / 230
uterus	32%	177.95	54 / 170	47%	5.90	216 / 459
ovary	10%	58.24	18 / 180	64%	8.77	276 / 430
tonsil	0%	0	0 / 0	73%	13.01	33 / 45
prostate	38%	239.53	94 / 245	30%	2.61	149 / 502
blood vessel	62%	617.79	834 / 1335	0%	0	0 / 0
heart	39%	273.64	338 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	15%	1.41	12 / 80
muscle	3%	15.77	23 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1