T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1ICAM1-ITGALICAM1_HUMAN - ITAL_HUMANLigand-ReceptorAdhesion by ICAM
2ICAM1-ITGAL+ITGB2ICAM1_HUMAN - Ligand-ReceptorAdhesion by ICAM

II. Literature review

[source]
NameT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
IDGO_0002291
collection_id

Biological process

Exact synonym

T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Description

The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.

External URL
Genes
ICAM1ITGALAPBB1IPFGL2