ABRACL report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	36 studies	34% ± 12%	Explore
CD8-positive, alpha-beta T cell	34 studies	43% ± 18%	Explore
CD4-positive, alpha-beta T cell	31 studies	48% ± 16%	Explore
T cell	27 studies	42% ± 16%	Explore
macrophage	26 studies	36% ± 12%	Explore
classical monocyte	25 studies	37% ± 13%	Explore
conventional dendritic cell	25 studies	38% ± 15%	Explore
non-classical monocyte	23 studies	54% ± 14%	Explore
regulatory T cell	23 studies	44% ± 15%	Explore
plasmacytoid dendritic cell	19 studies	41% ± 14%	Explore
monocyte	18 studies	38% ± 11%	Explore
mast cell	17 studies	36% ± 13%	Explore
B cell	17 studies	29% ± 14%	Explore
mature NK T cell	17 studies	38% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	36% ± 12%	Explore
gamma-delta T cell	16 studies	36% ± 17%	Explore
mucosal invariant T cell	15 studies	33% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	40% ± 12%	Explore
naive B cell	14 studies	25% ± 9%	Explore
plasma cell	13 studies	30% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	31% ± 13%	Explore
dendritic cell	13 studies	43% ± 23%	Explore
epithelial cell	12 studies	35% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	39% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	33% ± 8%	Explore
plasmablast	10 studies	39% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	46% ± 18%	Explore
endothelial cell	9 studies	24% ± 9%	Explore
memory B cell	8 studies	19% ± 4%	Explore
basal cell	8 studies	37% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	34% ± 10%	Explore
T follicular helper cell	8 studies	44% ± 7%	Explore
myeloid cell	8 studies	39% ± 10%	Explore
enterocyte	7 studies	29% ± 8%	Explore
progenitor cell	7 studies	32% ± 18%	Explore
innate lymphoid cell	7 studies	35% ± 8%	Explore
hematopoietic precursor cell	6 studies	43% ± 21%	Explore
club cell	6 studies	24% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	52% ± 22%	Explore
leukocyte	6 studies	36% ± 13%	Explore
epithelial cell of proximal tubule	6 studies	24% ± 8%	Explore
endothelial cell of artery	6 studies	19% ± 5%	Explore
hematopoietic stem cell	6 studies	39% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	49% ± 19%	Explore
CD4-positive helper T cell	5 studies	32% ± 8%	Explore
exhausted T cell	5 studies	49% ± 13%	Explore
mononuclear phagocyte	5 studies	38% ± 19%	Explore
pro-B cell	5 studies	38% ± 5%	Explore
ciliated cell	5 studies	41% ± 25%	Explore
T-helper 17 cell	5 studies	61% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	62% ± 22%	Explore
intermediate monocyte	5 studies	53% ± 15%	Explore
alveolar macrophage	4 studies	28% ± 6%	Explore
secretory cell	4 studies	42% ± 25%	Explore
goblet cell	4 studies	24% ± 6%	Explore
erythroblast	4 studies	24% ± 9%	Explore
precursor B cell	4 studies	37% ± 14%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	21% ± 3%	Explore
granulocyte	4 studies	33% ± 10%	Explore
group 3 innate lymphoid cell	4 studies	53% ± 12%	Explore
T-helper 1 cell	4 studies	61% ± 14%	Explore
respiratory goblet cell	3 studies	31% ± 12%	Explore
extravillous trophoblast	3 studies	27% ± 8%	Explore
common myeloid progenitor	3 studies	50% ± 19%	Explore
megakaryocyte	3 studies	41% ± 18%	Explore
immature B cell	3 studies	39% ± 13%	Explore
intraepithelial lymphocyte	3 studies	47% ± 12%	Explore
neutrophil	3 studies	21% ± 2%	Explore
germinal center B cell	3 studies	43% ± 3%	Explore
abnormal cell	3 studies	29% ± 9%	Explore
glutamatergic neuron	3 studies	20% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	44% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	55% ± 27%	Explore
enteroendocrine cell	3 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	37% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	42% ± 10%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	36% ± 13%	Explore
double negative thymocyte	3 studies	49% ± 23%	Explore
progenitor cell of mammary luminal epithelium	3 studies	21% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	35% ± 11%	Explore
lung	14 studies	28% ± 17%	Explore
intestine	9 studies	23% ± 7%	Explore
kidney	5 studies	28% ± 8%	Explore
bone marrow	5 studies	24% ± 8%	Explore
lymph node	5 studies	32% ± 4%	Explore
liver	5 studies	31% ± 9%	Explore
thymus	3 studies	53% ± 23%	Explore
breast	3 studies	22% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	818.84	653 / 653	100%	102.19	603 / 605
lung	100%	895.97	576 / 578	99%	140.47	1148 / 1155
breast	100%	644.35	458 / 459	99%	133.07	1105 / 1118
intestine	98%	1149.24	943 / 966	99%	147.92	524 / 527
bladder	95%	678.29	20 / 21	100%	160.06	502 / 504
skin	100%	892.35	1802 / 1809	94%	66.45	443 / 472
prostate	98%	506.91	239 / 245	95%	59.86	475 / 502
stomach	94%	657.61	338 / 359	98%	122.21	280 / 286
uterus	92%	412.43	157 / 170	99%	126.89	453 / 459
kidney	100%	1312.51	89 / 89	90%	55.49	808 / 901
esophagus	88%	615.36	1274 / 1445	100%	99.16	183 / 183
pancreas	89%	308.88	291 / 328	96%	85.30	170 / 178
liver	98%	914.86	222 / 226	50%	23.70	204 / 406
ovary	34%	87.95	61 / 180	97%	77.92	418 / 430
adrenal gland	74%	200.15	190 / 258	54%	23.01	125 / 230
brain	75%	382.20	1987 / 2642	42%	18.16	298 / 705
lymph node	0%	0	0 / 0	100%	220.70	29 / 29
spleen	100%	2399.64	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	126.51	45 / 45
ureter	0%	0	0 / 0	100%	50.06	1 / 1
peripheral blood	99%	1783.37	923 / 929	0%	0	0 / 0
adipose	99%	573.44	1190 / 1204	0%	0	0 / 0
heart	81%	245.63	697 / 861	0%	0	0 / 0
blood vessel	80%	318.99	1073 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	63%	26.04	50 / 80
muscle	3%	5.44	23 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0