UGP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	38 studies	29% ± 13%	Explore
natural killer cell	28 studies	23% ± 5%	Explore
CD4-positive, alpha-beta T cell	26 studies	26% ± 7%	Explore
CD8-positive, alpha-beta T cell	24 studies	22% ± 6%	Explore
T cell	23 studies	24% ± 7%	Explore
smooth muscle cell	23 studies	24% ± 6%	Explore
regulatory T cell	23 studies	37% ± 9%	Explore
pericyte	22 studies	26% ± 7%	Explore
endothelial cell	22 studies	27% ± 11%	Explore
macrophage	21 studies	27% ± 10%	Explore
endothelial cell of lymphatic vessel	21 studies	33% ± 8%	Explore
B cell	15 studies	21% ± 7%	Explore
astrocyte	15 studies	31% ± 14%	Explore
mast cell	14 studies	22% ± 6%	Explore
mature NK T cell	14 studies	23% ± 7%	Explore
epithelial cell	14 studies	36% ± 16%	Explore
basal cell	13 studies	31% ± 17%	Explore
ciliated cell	13 studies	35% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	25% ± 7%	Explore
gamma-delta T cell	13 studies	28% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	21% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	20% ± 3%	Explore
connective tissue cell	11 studies	26% ± 7%	Explore
monocyte	11 studies	23% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	20% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	23% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	23% ± 4%	Explore
mucosal invariant T cell	9 studies	20% ± 3%	Explore
adipocyte	9 studies	51% ± 14%	Explore
oligodendrocyte	9 studies	27% ± 8%	Explore
alveolar macrophage	8 studies	28% ± 8%	Explore
type I pneumocyte	8 studies	25% ± 7%	Explore
club cell	8 studies	27% ± 13%	Explore
classical monocyte	8 studies	23% ± 9%	Explore
mesothelial cell	8 studies	31% ± 14%	Explore
myofibroblast cell	8 studies	26% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	23% ± 6%	Explore
GABAergic neuron	7 studies	35% ± 19%	Explore
non-classical monocyte	7 studies	23% ± 9%	Explore
glutamatergic neuron	7 studies	44% ± 24%	Explore
microglial cell	7 studies	24% ± 5%	Explore
endothelial cell of vascular tree	7 studies	20% ± 3%	Explore
myeloid cell	7 studies	26% ± 9%	Explore
conventional dendritic cell	6 studies	29% ± 14%	Explore
epithelial cell of proximal tubule	6 studies	24% ± 6%	Explore
naive B cell	6 studies	18% ± 4%	Explore
cardiac muscle cell	6 studies	35% ± 5%	Explore
goblet cell	6 studies	31% ± 9%	Explore
ionocyte	5 studies	27% ± 9%	Explore
respiratory goblet cell	5 studies	29% ± 15%	Explore
secretory cell	5 studies	35% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	25% ± 7%	Explore
lymphocyte	5 studies	31% ± 11%	Explore
precursor B cell	5 studies	36% ± 10%	Explore
enterocyte	5 studies	25% ± 8%	Explore
vein endothelial cell	5 studies	19% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	26% ± 7%	Explore
innate lymphoid cell	5 studies	21% ± 4%	Explore
hepatocyte	5 studies	68% ± 13%	Explore
oligodendrocyte precursor cell	5 studies	25% ± 8%	Explore
leukocyte	5 studies	22% ± 6%	Explore
T follicular helper cell	5 studies	29% ± 15%	Explore
plasmacytoid dendritic cell	5 studies	21% ± 7%	Explore
deuterosomal cell	4 studies	21% ± 5%	Explore
duct epithelial cell	4 studies	26% ± 5%	Explore
squamous epithelial cell	4 studies	34% ± 23%	Explore
hematopoietic precursor cell	4 studies	38% ± 13%	Explore
progenitor cell	4 studies	20% ± 4%	Explore
neuron	4 studies	33% ± 8%	Explore
memory B cell	4 studies	18% ± 1%	Explore
retinal ganglion cell	4 studies	70% ± 27%	Explore
pro-B cell	4 studies	29% ± 5%	Explore
amacrine cell	4 studies	31% ± 12%	Explore
adventitial cell	4 studies	31% ± 8%	Explore
dendritic cell	4 studies	31% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	27% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
abnormal cell	4 studies	25% ± 9%	Explore
T-helper 17 cell	4 studies	25% ± 5%	Explore
interneuron	4 studies	35% ± 18%	Explore
pancreatic A cell	3 studies	27% ± 6%	Explore
capillary endothelial cell	3 studies	16% ± 1%	Explore
extravillous trophoblast	3 studies	80% ± 1%	Explore
placental villous trophoblast	3 studies	82% ± 3%	Explore
plasma cell	3 studies	27% ± 12%	Explore
retina horizontal cell	3 studies	30% ± 8%	Explore
mucus secreting cell	3 studies	31% ± 2%	Explore
serous secreting cell	3 studies	35% ± 13%	Explore
mononuclear phagocyte	3 studies	29% ± 11%	Explore
intraepithelial lymphocyte	3 studies	28% ± 11%	Explore
chondrocyte	3 studies	32% ± 13%	Explore
CD4-positive helper T cell	3 studies	26% ± 9%	Explore
myoepithelial cell	3 studies	23% ± 9%	Explore
muscle cell	3 studies	44% ± 13%	Explore
type II pneumocyte	3 studies	25% ± 12%	Explore
pancreatic ductal cell	3 studies	40% ± 19%	Explore
group 3 innate lymphoid cell	3 studies	25% ± 11%	Explore
transit amplifying cell	3 studies	28% ± 12%	Explore
double negative thymocyte	3 studies	44% ± 33%	Explore
platelet	3 studies	17% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	29% ± 13%	Explore
brain	14 studies	28% ± 17%	Explore
peripheral blood	10 studies	26% ± 8%	Explore
intestine	9 studies	22% ± 8%	Explore
kidney	8 studies	20% ± 4%	Explore
eye	7 studies	22% ± 7%	Explore
liver	6 studies	35% ± 10%	Explore
heart	5 studies	23% ± 3%	Explore
uterus	4 studies	26% ± 8%	Explore
breast	4 studies	21% ± 3%	Explore
adipose	4 studies	35% ± 18%	Explore
pancreas	3 studies	29% ± 7%	Explore
placenta	3 studies	66% ± 12%	Explore
bone marrow	3 studies	19% ± 4%	Explore
lymph node	3 studies	23% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	11427.66	459 / 459	100%	64.51	1118 / 1118
liver	100%	18664.77	226 / 226	100%	106.82	406 / 406
ovary	100%	4480.53	180 / 180	100%	32.44	430 / 430
esophagus	100%	7983.60	1444 / 1445	100%	42.58	183 / 183
uterus	100%	6883.60	170 / 170	100%	49.52	458 / 459
kidney	100%	6916.61	89 / 89	100%	49.47	899 / 901
prostate	100%	5412.47	244 / 245	100%	38.21	501 / 502
lung	99%	6659.00	574 / 578	100%	61.01	1155 / 1155
thymus	100%	5208.00	650 / 653	100%	52.82	603 / 605
bladder	100%	8593.10	21 / 21	99%	46.14	497 / 504
intestine	100%	10124.14	966 / 966	98%	45.87	519 / 527
brain	98%	7815.36	2594 / 2642	100%	41.68	704 / 705
stomach	100%	5268.28	359 / 359	98%	39.54	280 / 286
adrenal gland	100%	6666.34	257 / 258	98%	40.06	225 / 230
skin	100%	9345.22	1803 / 1809	96%	44.44	455 / 472
pancreas	89%	2960.08	293 / 328	100%	49.21	178 / 178
blood vessel	100%	13240.11	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	52.25	29 / 29
muscle	100%	26333.05	803 / 803	0%	0	0 / 0
spleen	100%	4850.96	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.62	45 / 45
ureter	0%	0	0 / 0	100%	15.86	1 / 1
adipose	100%	12401.05	1203 / 1204	0%	0	0 / 0
heart	95%	12186.77	822 / 861	0%	0	0 / 0
peripheral blood	87%	4438.22	811 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	81%	19.49	65 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007420	Biological process	brain development
GO_0019255	Biological process	glucose 1-phosphate metabolic process
GO_0005978	Biological process	glycogen biosynthetic process
GO_0006011	Biological process	UDP-glucose metabolic process
GO_0005977	Biological process	glycogen metabolic process
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003983	Molecular function	UTP:glucose-1-phosphate uridylyltransferase activity
GO_0005536	Molecular function	D-glucose binding
GO_0032557	Molecular function	pyrimidine ribonucleotide binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	UGP2
Protein name	UDP-glucose pyrophosphorylase 2 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)
Synonyms	UGP1
Description	FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. . FUNCTION: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. .
Accessions	ENST00000487640.5 F8WC70 ENST00000496334.6 ENST00000497883.5 A0A7I2YQ74 ENST00000466642.5 ENST00000475462.5 Q16851 ENST00000484142.2 ENST00000678974.1 ENST00000613823.2 ENST00000467400.5 ENST00000678951.1 F8WDA2 ENST00000676870.1 H7C500 F2Z3H1 C9J6Q0 C9JTZ5 ENST00000488245.6 ENST00000337130.10 [Q16851-1] ENST00000482668.5 A0A087WYS1 ENST00000676780.1 ENST00000394417.7 [Q16851-2] C9JWG0 ENST00000472047.5 ENST00000445915.6 Q53QE9 ENST00000497510.5 A0A7I2V2Q3 A0A7I2V4T0 ENST00000483108.5 C9JNZ1 ENST00000626380.2 A0A7I2V676 C9JVG3 C9J3M0 ENST00000677841.1 ENST00000679256.1 ENST00000467648.6 [Q16851-2] E7EUC7 ENST00000491621.5 F2Z3P4 ENST00000487042.5 C9JUW1 C9JQU9 ENST00000480679.5 ENST00000467999.6 ENST00000678298.1 ENST00000493222.5

UGP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review