TTC14 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	25 studies	23% ± 7%	Explore
B cell	21 studies	24% ± 7%	Explore
fibroblast	19 studies	24% ± 8%	Explore
endothelial cell	18 studies	29% ± 13%	Explore
naive B cell	18 studies	19% ± 5%	Explore
CD4-positive, alpha-beta T cell	17 studies	23% ± 9%	Explore
CD8-positive, alpha-beta T cell	16 studies	23% ± 9%	Explore
T cell	15 studies	20% ± 4%	Explore
regulatory T cell	15 studies	18% ± 3%	Explore
gamma-delta T cell	14 studies	22% ± 8%	Explore
astrocyte	14 studies	34% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	22% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	23% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	23% ± 10%	Explore
memory B cell	13 studies	19% ± 3%	Explore
plasmacytoid dendritic cell	12 studies	25% ± 7%	Explore
mature NK T cell	10 studies	21% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	23% ± 10%	Explore
microglial cell	10 studies	31% ± 9%	Explore
oligodendrocyte	10 studies	32% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	21% ± 5%	Explore
GABAergic neuron	9 studies	44% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	25% ± 10%	Explore
glutamatergic neuron	9 studies	53% ± 23%	Explore
oligodendrocyte precursor cell	9 studies	34% ± 15%	Explore
pericyte	9 studies	22% ± 6%	Explore
adipocyte	9 studies	29% ± 9%	Explore
macrophage	8 studies	29% ± 9%	Explore
amacrine cell	7 studies	29% ± 13%	Explore
mucosal invariant T cell	7 studies	18% ± 2%	Explore
endothelial cell of lymphatic vessel	6 studies	22% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
neuron	6 studies	30% ± 16%	Explore
interneuron	6 studies	47% ± 23%	Explore
epithelial cell	6 studies	37% ± 14%	Explore
mast cell	6 studies	22% ± 5%	Explore
retinal rod cell	6 studies	23% ± 4%	Explore
T follicular helper cell	6 studies	18% ± 3%	Explore
type I pneumocyte	6 studies	19% ± 5%	Explore
leukocyte	5 studies	21% ± 6%	Explore
non-classical monocyte	5 studies	27% ± 12%	Explore
mesothelial cell	5 studies	31% ± 14%	Explore
retina horizontal cell	5 studies	32% ± 8%	Explore
Mueller cell	5 studies	27% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
smooth muscle cell	5 studies	20% ± 4%	Explore
capillary endothelial cell	4 studies	20% ± 4%	Explore
retinal bipolar neuron	4 studies	30% ± 12%	Explore
myeloid cell	4 studies	20% ± 3%	Explore
retinal cone cell	4 studies	32% ± 11%	Explore
ciliated cell	4 studies	26% ± 8%	Explore
lymphocyte	4 studies	32% ± 9%	Explore
abnormal cell	4 studies	20% ± 4%	Explore
innate lymphoid cell	4 studies	20% ± 1%	Explore
dendritic cell	4 studies	26% ± 14%	Explore
connective tissue cell	4 studies	20% ± 8%	Explore
myofibroblast cell	4 studies	23% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	18% ± 2%	Explore
double negative thymocyte	4 studies	29% ± 12%	Explore
classical monocyte	3 studies	28% ± 11%	Explore
exhausted T cell	3 studies	27% ± 15%	Explore
glomerular endothelial cell	3 studies	20% ± 3%	Explore
podocyte	3 studies	27% ± 3%	Explore
endothelial cell of artery	3 studies	16% ± 1%	Explore
GABAergic interneuron	3 studies	32% ± 3%	Explore
granule cell	3 studies	26% ± 10%	Explore
retinal ganglion cell	3 studies	34% ± 5%	Explore
precursor B cell	3 studies	21% ± 4%	Explore
rod bipolar cell	3 studies	29% ± 6%	Explore
type II pneumocyte	3 studies	23% ± 5%	Explore
ependymal cell	3 studies	38% ± 14%	Explore
goblet cell	3 studies	19% ± 4%	Explore
alveolar macrophage	3 studies	24% ± 5%	Explore
monocyte	3 studies	22% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	22% ± 6%	Explore
basal cell	3 studies	40% ± 16%	Explore
hepatocyte	3 studies	28% ± 9%	Explore
immature B cell	3 studies	23% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	14 studies	40% ± 19%	Explore
peripheral blood	11 studies	24% ± 11%	Explore
lung	8 studies	20% ± 5%	Explore
eye	8 studies	27% ± 11%	Explore
liver	4 studies	24% ± 5%	Explore
adipose	4 studies	27% ± 7%	Explore
intestine	3 studies	25% ± 11%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	6469.37	245 / 245	100%	13.84	500 / 502
pancreas	100%	3319.36	327 / 328	99%	12.41	177 / 178
breast	100%	5104.13	459 / 459	98%	15.52	1097 / 1118
thymus	100%	9096.17	653 / 653	98%	14.62	592 / 605
brain	97%	2804.15	2566 / 2642	100%	16.84	705 / 705
lung	100%	5035.52	577 / 578	97%	11.53	1117 / 1155
esophagus	100%	4176.33	1442 / 1445	97%	11.34	177 / 183
bladder	100%	4952.52	21 / 21	95%	9.55	478 / 504
uterus	100%	7070.99	170 / 170	94%	11.32	433 / 459
adrenal gland	100%	3600.66	258 / 258	92%	6.86	211 / 230
kidney	100%	4787.97	89 / 89	91%	9.37	819 / 901
ovary	100%	8909.49	180 / 180	86%	7.40	371 / 430
intestine	100%	5144.08	966 / 966	86%	6.50	451 / 527
skin	99%	2823.03	1788 / 1809	84%	9.70	395 / 472
stomach	100%	3687.89	358 / 359	80%	6.61	229 / 286
liver	96%	1824.83	218 / 226	66%	4.13	269 / 406
spleen	100%	5510.53	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.19	1 / 1
adipose	100%	4547.39	1202 / 1204	0%	0	0 / 0
blood vessel	100%	5011.90	1332 / 1335	0%	0	0 / 0
heart	97%	2577.92	839 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	10.75	26 / 29
tonsil	0%	0	0 / 0	87%	7.60	39 / 45
muscle	81%	1219.11	649 / 803	0%	0	0 / 0
peripheral blood	58%	1421.08	543 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	43%	3.36	34 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0