TBC1D10C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0070373Biological processnegative regulation of ERK1 and ERK2 cascade
GO_0033173Biological processcalcineurin-NFAT signaling cascade
GO_0070371Biological processERK1 and ERK2 cascade
GO_0070885Biological processnegative regulation of calcineurin-NFAT signaling cascade
GO_1902017Biological processregulation of cilium assembly
GO_0042113Biological processB cell activation
GO_0090630Biological processactivation of GTPase activity
GO_0050869Biological processnegative regulation of B cell activation
GO_0031527Cellular componentfilopodium membrane
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameTBC1D10C
Protein nameTBC1 domain family, member 10C
Carabin (TBC1 domain family member 10C)
TBC1 domain family member 10C
Synonyms
DescriptionFUNCTION: Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. .

AccessionsB9A6L1
Q8IV04
E9PSB7
ENST00000312390.9 [Q8IV04-2]
ENST00000529635.5
ENST00000526387.5 [Q8IV04-2]
ENST00000542590.2 [Q8IV04-1]