RNASEH2C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	24 studies	24% ± 9%	Explore
fibroblast	24 studies	24% ± 10%	Explore
endothelial cell	22 studies	26% ± 10%	Explore
smooth muscle cell	21 studies	25% ± 8%	Explore
B cell	21 studies	25% ± 8%	Explore
pericyte	21 studies	26% ± 6%	Explore
classical monocyte	17 studies	26% ± 10%	Explore
endothelial cell of lymphatic vessel	15 studies	31% ± 8%	Explore
CD4-positive, alpha-beta T cell	14 studies	22% ± 8%	Explore
CD8-positive, alpha-beta T cell	14 studies	26% ± 6%	Explore
T cell	13 studies	21% ± 6%	Explore
naive B cell	13 studies	19% ± 4%	Explore
myofibroblast cell	13 studies	22% ± 7%	Explore
gamma-delta T cell	13 studies	23% ± 14%	Explore
plasma cell	12 studies	36% ± 12%	Explore
monocyte	12 studies	23% ± 8%	Explore
non-classical monocyte	12 studies	25% ± 11%	Explore
macrophage	11 studies	22% ± 9%	Explore
plasmacytoid dendritic cell	11 studies	26% ± 10%	Explore
conventional dendritic cell	10 studies	27% ± 14%	Explore
connective tissue cell	10 studies	25% ± 7%	Explore
memory B cell	10 studies	22% ± 5%	Explore
regulatory T cell	10 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	24% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	23% ± 4%	Explore
plasmablast	8 studies	46% ± 22%	Explore
mature NK T cell	8 studies	20% ± 5%	Explore
mast cell	7 studies	22% ± 11%	Explore
capillary endothelial cell	7 studies	19% ± 5%	Explore
epithelial cell	7 studies	37% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	21% ± 6%	Explore
vein endothelial cell	6 studies	17% ± 2%	Explore
basal cell	6 studies	28% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	23% ± 5%	Explore
mucosal invariant T cell	6 studies	18% ± 3%	Explore
hematopoietic precursor cell	5 studies	38% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 4%	Explore
endothelial cell of artery	5 studies	23% ± 2%	Explore
abnormal cell	5 studies	22% ± 3%	Explore
erythrocyte	5 studies	30% ± 19%	Explore
endothelial cell of vascular tree	5 studies	22% ± 2%	Explore
innate lymphoid cell	5 studies	22% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	19% ± 3%	Explore
leukocyte	4 studies	27% ± 14%	Explore
exhausted T cell	4 studies	23% ± 6%	Explore
mesothelial cell	4 studies	27% ± 19%	Explore
erythroblast	4 studies	38% ± 24%	Explore
hematopoietic stem cell	4 studies	27% ± 4%	Explore
pro-B cell	4 studies	30% ± 3%	Explore
myeloid cell	4 studies	32% ± 12%	Explore
precursor B cell	4 studies	31% ± 8%	Explore
ciliated cell	4 studies	33% ± 4%	Explore
T follicular helper cell	4 studies	17% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	29% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
mononuclear phagocyte	3 studies	31% ± 14%	Explore
glomerular endothelial cell	3 studies	21% ± 2%	Explore
progenitor cell	3 studies	38% ± 17%	Explore
neural crest cell	3 studies	24% ± 2%	Explore
lymphocyte	3 studies	36% ± 8%	Explore
type II pneumocyte	3 studies	30% ± 15%	Explore
intraepithelial lymphocyte	3 studies	26% ± 8%	Explore
germinal center B cell	3 studies	24% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	21% ± 1%	Explore
intermediate monocyte	3 studies	33% ± 14%	Explore
neuron	3 studies	29% ± 14%	Explore
muscle cell	3 studies	29% ± 17%	Explore
granulocyte monocyte progenitor cell	3 studies	45% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	39% ± 22%	Explore
enteroendocrine cell	3 studies	35% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 15%	Explore
T-helper 17 cell	3 studies	22% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	25% ± 8%	Explore
lung	8 studies	25% ± 7%	Explore
kidney	6 studies	19% ± 2%	Explore
intestine	6 studies	22% ± 11%	Explore
bone marrow	4 studies	21% ± 3%	Explore
uterus	4 studies	26% ± 12%	Explore
liver	4 studies	34% ± 26%	Explore
lymph node	4 studies	20% ± 5%	Explore
brain	4 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	3063.25	258 / 258	100%	26.52	230 / 230
ovary	100%	3407.35	180 / 180	100%	23.73	430 / 430
brain	100%	2284.03	2637 / 2642	100%	31.67	705 / 705
prostate	100%	3976.12	245 / 245	100%	28.03	501 / 502
uterus	100%	3921.92	170 / 170	100%	23.53	458 / 459
stomach	100%	2301.85	359 / 359	100%	15.85	285 / 286
intestine	100%	3102.70	966 / 966	100%	17.23	525 / 527
thymus	100%	2651.74	653 / 653	100%	21.73	602 / 605
esophagus	100%	2777.29	1445 / 1445	99%	11.48	182 / 183
bladder	100%	3341.76	21 / 21	99%	20.42	500 / 504
skin	100%	1560.42	1806 / 1809	99%	21.58	469 / 472
liver	100%	1141.85	225 / 226	100%	14.58	404 / 406
lung	100%	2003.46	576 / 578	99%	14.97	1148 / 1155
pancreas	99%	1183.78	326 / 328	99%	18.77	177 / 178
breast	100%	2423.70	459 / 459	99%	16.82	1102 / 1118
kidney	100%	2465.03	89 / 89	99%	16.96	888 / 901
adipose	100%	2298.54	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	23.31	80 / 80
lymph node	0%	0	0 / 0	100%	56.91	29 / 29
spleen	100%	3529.54	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	17.75	45 / 45
ureter	0%	0	0 / 0	100%	19.45	1 / 1
blood vessel	100%	3271.80	1334 / 1335	0%	0	0 / 0
heart	100%	1923.70	858 / 861	0%	0	0 / 0
peripheral blood	97%	1634.28	905 / 929	0%	0	0 / 0
muscle	95%	959.63	764 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006298	Biological process	mismatch repair
GO_0006401	Biological process	RNA catabolic process
GO_0032299	Cellular component	ribonuclease H2 complex
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	RNASEH2C
Protein name	Ribonuclease H2 subunit C Ribonuclease H2 subunit C (RNase H2 subunit C) (Aicardi-Goutieres syndrome 3 protein) (AGS3) (RNase H1 small subunit) (Ribonuclease HI subunit C)
Synonyms	AYP1
Description	FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .
Accessions	ENST00000527610.1 ENST00000534482.6 ENST00000308418.10 Q8TDP1 E9PN81 ENST00000531596.6 ENST00000644142.1

RNASEH2C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review