RNASEH2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010467Biological processgene expression
GO_0048146Biological processpositive regulation of fibroblast proliferation
GO_2000001Biological processregulation of DNA damage checkpoint
GO_0006298Biological processmismatch repair
GO_0010389Biological processregulation of G2/M transition of mitotic cell cycle
GO_0001701Biological processin utero embryonic development
GO_0048144Biological processfibroblast proliferation
GO_0010629Biological processnegative regulation of gene expression
GO_0009259Biological processribonucleotide metabolic process
GO_0006401Biological processRNA catabolic process
GO_0032299Cellular componentribonuclease H2 complex
GO_0005654Cellular componentnucleoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRNASEH2B
Protein nameRibonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B)
Ribonuclease H2 subunit B
Ribonuclease H2 subunit B (Ribonuclease HI subunit B)
SynonymsDLEU8
DescriptionFUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .

AccessionsQ8N451
A0A2R8YEK5
A0A2R8YE60
ENST00000645955.1
ENST00000646731.1
A0A2R8YEC1
ENST00000642207.1
A0A2R8YEH2
ENST00000643462.1
A0A2R8YCX2
A0A1B0GUE7
ENST00000643774.1
A0A2R8Y6Y1
A0A2R8YEB4
A0A2R8Y883
ENST00000642721.1
A0A1B0GTJ2
ENST00000336617.8 [Q5TBB1-1]
ENST00000643215.1
A0A2R8Y6M7
A0A2R8Y6Q6
A0A2R8Y7R8
ENST00000643159.1
ENST00000645990.1
ENST00000645912.1
ENST00000643529.1
A0A087WXR7
ENST00000645618.1
ENST00000422660.6 [Q5TBB1-2]
ENST00000616907.2
ENST00000646709.1
ENST00000646092.1
ENST00000636524
ENST00000644518.1
ENST00000643405.1
A0A2R8Y4Y9
A0A2R8Y4S2
ENST00000645188.1
A0A2R8Y7A3
ENST00000642454.1
ENST00000647387.1
ENST00000644297.1
A0A2R8Y7M7
A0A2R8Y687
ENST00000611510.5
Q5TBB1
ENST00000643682.1
A0A2R8YCP1
ENST00000644425.1
A0A2R8YGP2
ENST00000644034.1
A0A2R8Y7Q3
ENST00000644183.1
A0A2R8YEQ4
A0A2R8Y459
A0A087WZJ6
ENST00000637648.2
A0A2R8Y6U1
A0A2R8YCJ4
ENST00000642995.1
A0A2R8Y761
ENST00000645370.1
ENST00000646960.1
A0A2R8YEU9
ENST00000646339.1