Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1400.03 | 1445 / 1445 | 100% | 3.69 | 183 / 183 |
breast | 100% | 1203.76 | 459 / 459 | 100% | 3.83 | 1117 / 1118 |
brain | 100% | 1041.96 | 2634 / 2642 | 100% | 3.52 | 705 / 705 |
lung | 100% | 1262.82 | 577 / 578 | 100% | 3.90 | 1153 / 1155 |
pancreas | 100% | 963.63 | 328 / 328 | 99% | 3.31 | 177 / 178 |
thymus | 100% | 1595.58 | 653 / 653 | 99% | 7.65 | 601 / 605 |
ovary | 100% | 1248.51 | 180 / 180 | 99% | 2.92 | 427 / 430 |
stomach | 100% | 1027.85 | 359 / 359 | 99% | 4.62 | 284 / 286 |
intestine | 100% | 1644.10 | 966 / 966 | 99% | 4.96 | 523 / 527 |
prostate | 100% | 1501.93 | 245 / 245 | 99% | 2.82 | 496 / 502 |
uterus | 100% | 1841.96 | 170 / 170 | 99% | 4.41 | 453 / 459 |
bladder | 100% | 1557.76 | 21 / 21 | 98% | 4.19 | 496 / 504 |
skin | 100% | 971.34 | 1807 / 1809 | 94% | 3.43 | 445 / 472 |
kidney | 100% | 842.06 | 89 / 89 | 93% | 2.39 | 842 / 901 |
adrenal gland | 100% | 1034.36 | 258 / 258 | 93% | 2.23 | 214 / 230 |
liver | 92% | 363.17 | 209 / 226 | 76% | 1.41 | 307 / 406 |
adipose | 100% | 1179.32 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1169.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.14 | 29 / 29 |
spleen | 100% | 1763.65 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 3.93 | 45 / 45 |
heart | 98% | 959.31 | 843 / 861 | 0% | 0 | 0 / 0 |
muscle | 97% | 561.45 | 779 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 93% | 1112.99 | 860 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 75% | 1.54 | 60 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010467 | Biological process | gene expression |
GO_0048146 | Biological process | positive regulation of fibroblast proliferation |
GO_2000001 | Biological process | regulation of DNA damage checkpoint |
GO_0006298 | Biological process | mismatch repair |
GO_0010389 | Biological process | regulation of G2/M transition of mitotic cell cycle |
GO_0001701 | Biological process | in utero embryonic development |
GO_0048144 | Biological process | fibroblast proliferation |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0009259 | Biological process | ribonucleotide metabolic process |
GO_0006401 | Biological process | RNA catabolic process |
GO_0032299 | Cellular component | ribonuclease H2 complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | RNASEH2B |
Protein name | Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B) Ribonuclease H2 subunit B Ribonuclease H2 subunit B (Ribonuclease HI subunit B) |
Synonyms | DLEU8 |
Description | FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . FUNCTION: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. . |
Accessions | Q8N451 A0A2R8YEK5 A0A2R8YE60 ENST00000645955.1 ENST00000646731.1 A0A2R8YEC1 ENST00000642207.1 A0A2R8YEH2 ENST00000643462.1 A0A2R8YCX2 A0A1B0GUE7 ENST00000643774.1 A0A2R8Y6Y1 A0A2R8YEB4 A0A2R8Y883 ENST00000642721.1 A0A1B0GTJ2 ENST00000336617.8 [Q5TBB1-1] ENST00000643215.1 A0A2R8Y6M7 A0A2R8Y6Q6 A0A2R8Y7R8 ENST00000643159.1 ENST00000645990.1 ENST00000645912.1 ENST00000643529.1 A0A087WXR7 ENST00000645618.1 ENST00000422660.6 [Q5TBB1-2] ENST00000616907.2 ENST00000646709.1 ENST00000646092.1 ENST00000636524 ENST00000644518.1 ENST00000643405.1 A0A2R8Y4Y9 A0A2R8Y4S2 ENST00000645188.1 A0A2R8Y7A3 ENST00000642454.1 ENST00000647387.1 ENST00000644297.1 A0A2R8Y7M7 A0A2R8Y687 ENST00000611510.5 Q5TBB1 ENST00000643682.1 A0A2R8YCP1 ENST00000644425.1 A0A2R8YGP2 ENST00000644034.1 A0A2R8Y7Q3 ENST00000644183.1 A0A2R8YEQ4 A0A2R8Y459 A0A087WZJ6 ENST00000637648.2 A0A2R8Y6U1 A0A2R8YCJ4 ENST00000642995.1 A0A2R8Y761 ENST00000645370.1 ENST00000646960.1 A0A2R8YEU9 ENST00000646339.1 |