PPP2R5E | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	25 studies	31% ± 13%	Explore
fibroblast	15 studies	23% ± 7%	Explore
natural killer cell	14 studies	22% ± 5%	Explore
pericyte	14 studies	22% ± 8%	Explore
macrophage	13 studies	29% ± 12%	Explore
smooth muscle cell	12 studies	24% ± 6%	Explore
glutamatergic neuron	11 studies	48% ± 26%	Explore
microglial cell	11 studies	33% ± 12%	Explore
ciliated cell	11 studies	30% ± 12%	Explore
GABAergic neuron	10 studies	46% ± 25%	Explore
astrocyte	10 studies	36% ± 16%	Explore
oligodendrocyte	10 studies	32% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	22% ± 4%	Explore
CD8-positive, alpha-beta T cell	9 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	9 studies	38% ± 14%	Explore
epithelial cell	9 studies	40% ± 17%	Explore
type I pneumocyte	8 studies	30% ± 11%	Explore
B cell	8 studies	22% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	22% ± 3%	Explore
adipocyte	8 studies	25% ± 6%	Explore
neuron	7 studies	45% ± 16%	Explore
myeloid cell	7 studies	28% ± 5%	Explore
amacrine cell	7 studies	29% ± 8%	Explore
retinal cone cell	7 studies	42% ± 10%	Explore
retinal rod cell	7 studies	39% ± 12%	Explore
T cell	7 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	7 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
basal cell	6 studies	37% ± 17%	Explore
club cell	6 studies	32% ± 9%	Explore
retina horizontal cell	6 studies	56% ± 14%	Explore
dendritic cell	6 studies	28% ± 7%	Explore
type II pneumocyte	6 studies	32% ± 7%	Explore
monocyte	6 studies	26% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 4%	Explore
myofibroblast cell	5 studies	25% ± 8%	Explore
interneuron	5 studies	58% ± 21%	Explore
retinal ganglion cell	5 studies	32% ± 13%	Explore
mast cell	5 studies	20% ± 5%	Explore
goblet cell	5 studies	32% ± 22%	Explore
leukocyte	4 studies	24% ± 7%	Explore
hematopoietic precursor cell	4 studies	26% ± 10%	Explore
mature NK T cell	4 studies	24% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
non-classical monocyte	4 studies	23% ± 8%	Explore
granule cell	4 studies	32% ± 5%	Explore
retinal bipolar neuron	4 studies	27% ± 5%	Explore
cardiac muscle cell	4 studies	25% ± 3%	Explore
vein endothelial cell	4 studies	28% ± 15%	Explore
lymphocyte	4 studies	33% ± 8%	Explore
Mueller cell	4 studies	23% ± 6%	Explore
endothelial cell of vascular tree	4 studies	26% ± 14%	Explore
gamma-delta T cell	4 studies	25% ± 8%	Explore
naive B cell	4 studies	19% ± 2%	Explore
regulatory T cell	4 studies	18% ± 2%	Explore
classical monocyte	3 studies	25% ± 7%	Explore
glial cell	3 studies	25% ± 7%	Explore
progenitor cell	3 studies	27% ± 2%	Explore
mucosal invariant T cell	3 studies	19% ± 3%	Explore
plasma cell	3 studies	34% ± 3%	Explore
retinal pigment epithelial cell	3 studies	31% ± 18%	Explore
mesothelial cell	3 studies	22% ± 4%	Explore
mononuclear phagocyte	3 studies	24% ± 5%	Explore
GABAergic amacrine cell	3 studies	37% ± 5%	Explore
OFF-bipolar cell	3 studies	31% ± 7%	Explore
ON-bipolar cell	3 studies	29% ± 6%	Explore
glycinergic amacrine cell	3 studies	28% ± 5%	Explore
rod bipolar cell	3 studies	31% ± 7%	Explore
cholangiocyte	3 studies	53% ± 19%	Explore
hepatocyte	3 studies	49% ± 29%	Explore
connective tissue cell	3 studies	24% ± 2%	Explore
hematopoietic stem cell	3 studies	19% ± 3%	Explore
enteroendocrine cell	3 studies	23% ± 4%	Explore
intestinal crypt stem cell	3 studies	19% ± 3%	Explore
alveolar macrophage	3 studies	37% ± 10%	Explore
capillary endothelial cell	3 studies	21% ± 4%	Explore
respiratory goblet cell	3 studies	33% ± 12%	Explore
transit amplifying cell	3 studies	41% ± 28%	Explore
plasmacytoid dendritic cell	3 studies	21% ± 3%	Explore
abnormal cell	3 studies	27% ± 14%	Explore
mucus secreting cell	3 studies	29% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	40% ± 20%	Explore
lung	10 studies	25% ± 7%	Explore
eye	8 studies	35% ± 10%	Explore
heart	4 studies	22% ± 3%	Explore
peripheral blood	3 studies	27% ± 1%	Explore
liver	3 studies	36% ± 11%	Explore
intestine	3 studies	22% ± 5%	Explore
adipose	3 studies	24% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	2538.62	459 / 459	100%	25.76	1118 / 1118
esophagus	100%	2899.77	1445 / 1445	100%	27.47	183 / 183
lung	100%	2528.55	578 / 578	100%	22.77	1155 / 1155
uterus	100%	2598.85	170 / 170	100%	19.84	459 / 459
thymus	100%	2750.80	653 / 653	100%	21.20	604 / 605
prostate	100%	2169.79	245 / 245	100%	15.86	501 / 502
brain	100%	2051.43	2632 / 2642	100%	19.93	705 / 705
ovary	100%	2161.84	180 / 180	100%	14.90	428 / 430
bladder	100%	3099.62	21 / 21	99%	17.89	500 / 504
intestine	100%	2731.55	966 / 966	99%	17.58	520 / 527
stomach	100%	1753.36	359 / 359	99%	18.26	282 / 286
pancreas	99%	1072.83	325 / 328	99%	17.29	176 / 178
kidney	100%	1822.15	89 / 89	98%	14.93	881 / 901
adrenal gland	100%	2205.31	258 / 258	96%	17.02	221 / 230
skin	100%	2893.16	1808 / 1809	96%	16.78	452 / 472
liver	100%	1325.54	226 / 226	94%	9.17	380 / 406
adipose	100%	2649.89	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2930.14	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	16.49	29 / 29
muscle	100%	2343.13	803 / 803	0%	0	0 / 0
spleen	100%	1992.78	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	20.36	45 / 45
ureter	0%	0	0 / 0	100%	8.26	1 / 1
heart	97%	1621.59	837 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	13.92	75 / 80
peripheral blood	86%	1614.90	795 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007165	Biological process	signal transduction
GO_0006470	Biological process	protein dephosphorylation
GO_0000159	Cellular component	protein phosphatase type 2A complex
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0072542	Molecular function	protein phosphatase activator activity
GO_0019888	Molecular function	protein phosphatase regulator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PPP2R5E
Protein name	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon) PPP2R5E protein
Synonyms
Description	FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. . FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. .
Accessions	Q86XZ2 ENST00000555899.1 [Q16537-2] Q562F2 Q58EX4 ENST00000337537.8 [Q16537-1] Q16537 B5BTZ7 ENST00000422769.6 [Q16537-3]

PPP2R5E report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review