PIN4 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	16 studies	27% ± 11%	Explore
fibroblast	14 studies	24% ± 9%	Explore
smooth muscle cell	13 studies	20% ± 6%	Explore
ciliated cell	12 studies	32% ± 15%	Explore
pericyte	12 studies	23% ± 7%	Explore
natural killer cell	11 studies	19% ± 4%	Explore
endothelial cell of lymphatic vessel	10 studies	24% ± 8%	Explore
macrophage	9 studies	23% ± 9%	Explore
epithelial cell	9 studies	37% ± 20%	Explore
connective tissue cell	8 studies	23% ± 8%	Explore
capillary endothelial cell	7 studies	19% ± 5%	Explore
epithelial cell of proximal tubule	7 studies	27% ± 10%	Explore
abnormal cell	7 studies	24% ± 7%	Explore
basal cell	6 studies	32% ± 17%	Explore
myofibroblast cell	6 studies	23% ± 6%	Explore
astrocyte	6 studies	24% ± 6%	Explore
neuron	6 studies	30% ± 15%	Explore
CD8-positive, alpha-beta T cell	6 studies	18% ± 2%	Explore
non-classical monocyte	5 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 1%	Explore
classical monocyte	5 studies	22% ± 10%	Explore
conventional dendritic cell	5 studies	31% ± 16%	Explore
progenitor cell	5 studies	19% ± 3%	Explore
endothelial cell of artery	5 studies	18% ± 3%	Explore
vein endothelial cell	5 studies	21% ± 6%	Explore
B cell	5 studies	22% ± 9%	Explore
kidney loop of Henle epithelial cell	4 studies	21% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	20% ± 3%	Explore
enterocyte	4 studies	18% ± 2%	Explore
endothelial cell of vascular tree	4 studies	19% ± 3%	Explore
regulatory T cell	4 studies	19% ± 2%	Explore
GABAergic neuron	4 studies	35% ± 8%	Explore
glutamatergic neuron	4 studies	44% ± 6%	Explore
enteroendocrine cell	4 studies	30% ± 15%	Explore
goblet cell	4 studies	27% ± 14%	Explore
oligodendrocyte	4 studies	25% ± 6%	Explore
plasmacytoid dendritic cell	4 studies	21% ± 5%	Explore
deuterosomal cell	3 studies	21% ± 3%	Explore
pancreatic A cell	3 studies	27% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	30% ± 4%	Explore
neural crest cell	3 studies	23% ± 2%	Explore
lymphocyte	3 studies	21% ± 7%	Explore
plasma cell	3 studies	28% ± 12%	Explore
brush cell	3 studies	30% ± 11%	Explore
club cell	3 studies	24% ± 2%	Explore
precursor B cell	3 studies	27% ± 7%	Explore
pro-B cell	3 studies	26% ± 2%	Explore
type I pneumocyte	3 studies	29% ± 12%	Explore
erythroblast	3 studies	35% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
exhausted T cell	3 studies	16% ± 1%	Explore
intestinal crypt stem cell	3 studies	22% ± 7%	Explore
interneuron	3 studies	38% ± 10%	Explore
naive B cell	3 studies	16% ± 1%	Explore
gamma-delta T cell	3 studies	32% ± 21%	Explore
hepatocyte	3 studies	48% ± 30%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 5%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	9 studies	28% ± 11%	Explore
kidney	8 studies	18% ± 3%	Explore
peripheral blood	6 studies	20% ± 5%	Explore
brain	6 studies	29% ± 11%	Explore
intestine	5 studies	23% ± 11%	Explore
liver	4 studies	34% ± 21%	Explore
pancreas	3 studies	28% ± 3%	Explore
eye	3 studies	29% ± 10%	Explore
thymus	3 studies	29% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	832.17	258 / 258	100%	14.46	230 / 230
bladder	100%	808.95	21 / 21	100%	15.34	504 / 504
brain	100%	877.93	2642 / 2642	100%	13.76	705 / 705
esophagus	100%	807.90	1445 / 1445	100%	11.90	183 / 183
kidney	100%	1024.17	89 / 89	100%	11.91	901 / 901
ovary	100%	895.00	180 / 180	100%	14.19	430 / 430
prostate	100%	954.36	245 / 245	100%	16.30	502 / 502
thymus	100%	1043.09	653 / 653	100%	21.90	605 / 605
uterus	100%	945.44	170 / 170	100%	18.71	458 / 459
liver	100%	784.50	226 / 226	100%	14.27	405 / 406
stomach	100%	722.98	359 / 359	100%	13.43	285 / 286
intestine	100%	867.68	966 / 966	100%	13.09	525 / 527
lung	100%	659.76	576 / 578	100%	12.09	1154 / 1155
breast	100%	839.02	459 / 459	99%	16.06	1112 / 1118
skin	100%	724.55	1808 / 1809	99%	11.26	468 / 472
pancreas	99%	441.18	326 / 328	99%	11.59	177 / 178
adipose	100%	747.64	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	14.58	29 / 29
spleen	100%	799.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	13.77	45 / 45
ureter	0%	0	0 / 0	100%	10.71	1 / 1
blood vessel	100%	793.39	1334 / 1335	0%	0	0 / 0
muscle	100%	670.53	800 / 803	0%	0	0 / 0
heart	99%	697.71	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	10.83	79 / 80
peripheral blood	50%	241.87	460 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0