MRPL18 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	20 studies	22% ± 5%	Explore
natural killer cell	20 studies	22% ± 8%	Explore
CD4-positive, alpha-beta T cell	20 studies	22% ± 6%	Explore
fibroblast	18 studies	26% ± 11%	Explore
conventional dendritic cell	16 studies	30% ± 14%	Explore
endothelial cell	16 studies	31% ± 11%	Explore
macrophage	16 studies	25% ± 11%	Explore
smooth muscle cell	16 studies	25% ± 7%	Explore
ciliated cell	15 studies	34% ± 15%	Explore
non-classical monocyte	15 studies	22% ± 10%	Explore
pericyte	15 studies	22% ± 7%	Explore
CD8-positive, alpha-beta T cell	13 studies	23% ± 6%	Explore
regulatory T cell	12 studies	22% ± 6%	Explore
basal cell	11 studies	30% ± 12%	Explore
epithelial cell	11 studies	36% ± 20%	Explore
T cell	10 studies	24% ± 8%	Explore
connective tissue cell	10 studies	24% ± 5%	Explore
endothelial cell of vascular tree	9 studies	22% ± 3%	Explore
myofibroblast cell	8 studies	26% ± 13%	Explore
monocyte	8 studies	27% ± 8%	Explore
memory B cell	8 studies	20% ± 3%	Explore
endothelial cell of lymphatic vessel	7 studies	20% ± 7%	Explore
plasma cell	7 studies	29% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 3%	Explore
classical monocyte	6 studies	23% ± 10%	Explore
leukocyte	6 studies	33% ± 10%	Explore
dendritic cell	6 studies	46% ± 23%	Explore
mast cell	6 studies	20% ± 4%	Explore
gamma-delta T cell	6 studies	29% ± 20%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 9%	Explore
plasmablast	5 studies	39% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
mature NK T cell	5 studies	20% ± 2%	Explore
progenitor cell	5 studies	28% ± 16%	Explore
epithelial cell of proximal tubule	5 studies	20% ± 2%	Explore
abnormal cell	5 studies	24% ± 5%	Explore
innate lymphoid cell	5 studies	28% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	23% ± 5%	Explore
naive B cell	5 studies	20% ± 6%	Explore
secretory cell	5 studies	26% ± 8%	Explore
hematopoietic precursor cell	4 studies	31% ± 16%	Explore
mononuclear phagocyte	4 studies	27% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	18% ± 3%	Explore
kidney loop of Henle epithelial cell	4 studies	18% ± 1%	Explore
vein endothelial cell	4 studies	16% ± 1%	Explore
erythroblast	4 studies	33% ± 16%	Explore
myeloid cell	4 studies	29% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	22% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	19% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	22% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	23% ± 4%	Explore
transit amplifying cell	4 studies	20% ± 4%	Explore
deuterosomal cell	3 studies	28% ± 3%	Explore
glomerular endothelial cell	3 studies	28% ± 15%	Explore
renal alpha-intercalated cell	3 studies	28% ± 11%	Explore
enterocyte	3 studies	17% ± 1%	Explore
neural crest cell	3 studies	19% ± 2%	Explore
retinal ganglion cell	3 studies	47% ± 27%	Explore
lymphocyte	3 studies	27% ± 11%	Explore
club cell	3 studies	25% ± 6%	Explore
immature B cell	3 studies	29% ± 6%	Explore
pro-B cell	3 studies	22% ± 1%	Explore
retina horizontal cell	3 studies	23% ± 9%	Explore
retinal cone cell	3 studies	37% ± 14%	Explore
retinal rod cell	3 studies	23% ± 5%	Explore
Mueller cell	3 studies	25% ± 4%	Explore
germinal center B cell	3 studies	20% ± 5%	Explore
precursor B cell	3 studies	32% ± 15%	Explore
luminal cell of prostate epithelium	3 studies	31% ± 3%	Explore
enteroendocrine cell	3 studies	27% ± 10%	Explore
goblet cell	3 studies	28% ± 9%	Explore
intestinal crypt stem cell	3 studies	24% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 15%	Explore
keratinocyte	3 studies	18% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	27% ± 9%	Explore
kidney	7 studies	21% ± 3%	Explore
intestine	7 studies	23% ± 9%	Explore
peripheral blood	6 studies	21% ± 6%	Explore
liver	4 studies	28% ± 19%	Explore
brain	4 studies	22% ± 4%	Explore
eye	3 studies	28% ± 7%	Explore
uterus	3 studies	25% ± 13%	Explore
lymph node	3 studies	17% ± 3%	Explore
prostate	3 studies	26% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2477.42	258 / 258	100%	112.09	230 / 230
esophagus	100%	2126.58	1445 / 1445	100%	108.15	183 / 183
liver	100%	1597.83	226 / 226	100%	92.74	406 / 406
ovary	100%	1965.92	180 / 180	100%	118.90	430 / 430
prostate	100%	2058.04	245 / 245	100%	132.68	502 / 502
stomach	100%	1684.90	359 / 359	100%	129.02	286 / 286
uterus	100%	2174.15	170 / 170	100%	151.21	459 / 459
skin	100%	2053.84	1808 / 1809	100%	100.97	472 / 472
breast	100%	1795.72	459 / 459	100%	125.27	1117 / 1118
brain	100%	2123.62	2639 / 2642	100%	115.01	705 / 705
thymus	100%	1778.49	653 / 653	100%	114.92	604 / 605
intestine	100%	2227.98	966 / 966	100%	136.48	526 / 527
bladder	100%	2287.43	21 / 21	100%	130.78	503 / 504
pancreas	100%	998.87	327 / 328	100%	92.90	178 / 178
kidney	100%	2127.40	89 / 89	100%	90.74	898 / 901
lung	100%	1791.24	576 / 578	100%	123.56	1155 / 1155
adipose	100%	1944.06	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	89.66	80 / 80
lymph node	0%	0	0 / 0	100%	137.22	29 / 29
spleen	100%	1570.46	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	136.43	45 / 45
ureter	0%	0	0 / 0	100%	48.66	1 / 1
blood vessel	100%	2271.76	1334 / 1335	0%	0	0 / 0
muscle	100%	1694.41	802 / 803	0%	0	0 / 0
heart	99%	1681.17	849 / 861	0%	0	0 / 0
peripheral blood	89%	1169.72	828 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006412	Biological process	translation
GO_0032543	Biological process	mitochondrial translation
GO_0035928	Biological process	rRNA import into mitochondrion
GO_0005615	Cellular component	extracellular space
GO_0005761	Cellular component	mitochondrial ribosome
GO_0005762	Cellular component	mitochondrial large ribosomal subunit
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0008097	Molecular function	5S rRNA binding
GO_0003735	Molecular function	structural constituent of ribosome
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MRPL18
Protein name	Mitochondrial ribosomal protein L18, isoform CRA_b (cDNA FLJ76688, highly similar to Homo sapiens HSPC071 mRNA) Large ribosomal subunit protein uL18m (39S ribosomal protein L18, mitochondrial) (L18mt) (MRP-L18)
Synonyms	HSPC071 hCG_34030
Description	FUNCTION: Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. .
Accessions	Q9H0U6 A8K9D2 ENST00000367034.5

MRPL18 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review