Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3401.39 | 1445 / 1445 | 100% | 38.31 | 183 / 183 |
lung | 100% | 3750.26 | 578 / 578 | 100% | 49.43 | 1153 / 1155 |
brain | 100% | 3018.10 | 2636 / 2642 | 100% | 43.38 | 705 / 705 |
stomach | 100% | 2810.93 | 359 / 359 | 100% | 45.09 | 285 / 286 |
breast | 100% | 3680.22 | 459 / 459 | 100% | 49.51 | 1114 / 1118 |
intestine | 100% | 4137.05 | 966 / 966 | 100% | 51.77 | 525 / 527 |
ovary | 100% | 4255.67 | 180 / 180 | 100% | 50.68 | 428 / 430 |
prostate | 100% | 3325.65 | 245 / 245 | 99% | 36.28 | 499 / 502 |
thymus | 100% | 4942.76 | 653 / 653 | 99% | 82.67 | 601 / 605 |
kidney | 100% | 4216.51 | 89 / 89 | 99% | 69.38 | 895 / 901 |
bladder | 100% | 3825.29 | 21 / 21 | 99% | 46.67 | 500 / 504 |
uterus | 100% | 3832.40 | 170 / 170 | 99% | 52.06 | 455 / 459 |
liver | 100% | 2138.59 | 226 / 226 | 97% | 31.01 | 394 / 406 |
adrenal gland | 100% | 4235.08 | 258 / 258 | 97% | 39.73 | 223 / 230 |
skin | 100% | 3595.66 | 1808 / 1809 | 96% | 41.74 | 455 / 472 |
pancreas | 97% | 1349.77 | 318 / 328 | 98% | 49.04 | 175 / 178 |
adipose | 100% | 3521.73 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3780.66 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 82.97 | 29 / 29 |
spleen | 100% | 5857.46 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 66.89 | 45 / 45 |
muscle | 100% | 2439.14 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 2765.71 | 850 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 3825.59 | 906 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 29.99 | 75 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006730 | Biological process | one-carbon metabolic process |
GO_0006556 | Biological process | S-adenosylmethionine biosynthetic process |
GO_0048269 | Cellular component | methionine adenosyltransferase complex |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0019899 | Molecular function | enzyme binding |
GO_0005515 | Molecular function | protein binding |
GO_0048270 | Molecular function | methionine adenosyltransferase regulator activity |
Gene name | MAT2B |
Protein name | Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase) |
Synonyms | hCG_37711 Nbla02999 TGR UNQ2435/PRO4995 MSTP045 |
Description | FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine . Can bind NADP (in vitro) . . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. . |
Accessions | H7C0X7 A0A8Q3WK84 A0A8Q3WK80 ENST00000695026.1 ENST00000694939.1 ENST00000280969.9 [Q9NZL9-2] ENST00000694954.1 ENST00000694938.1 ENST00000694941.1 ENST00000695028.1 ENST00000694947.1 A0A8Q3WLC0 Q9NZL9 ENST00000694946.1 ENST00000695027.1 A0A8Q3SIE5 ENST00000695034.1 ENST00000695029.1 ENST00000694955.1 ENST00000321757.11 [Q9NZL9-1] A0A8Q3WK93 ENST00000520449.2 ENST00000695025.1 ENST00000518095.5 [Q9NZL9-3] A0A8Q3WLP1 A0A8Q3WK74 A0A8Q3WKR9 ENST00000694952.1 E5RJR3 ENST00000421814.7 ENST00000694943.1 [Q9NZL9-3] ENST00000694940.1 |