MAML2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	42% ± 19%	Explore
fibroblast	24 studies	49% ± 23%	Explore
macrophage	21 studies	46% ± 25%	Explore
pericyte	20 studies	49% ± 25%	Explore
astrocyte	19 studies	75% ± 14%	Explore
smooth muscle cell	17 studies	40% ± 21%	Explore
microglial cell	16 studies	74% ± 14%	Explore
oligodendrocyte precursor cell	15 studies	79% ± 19%	Explore
oligodendrocyte	14 studies	38% ± 12%	Explore
CD4-positive, alpha-beta T cell	13 studies	30% ± 13%	Explore
T cell	12 studies	36% ± 22%	Explore
endothelial cell of lymphatic vessel	12 studies	45% ± 23%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	28% ± 14%	Explore
adipocyte	11 studies	61% ± 18%	Explore
ciliated cell	10 studies	44% ± 26%	Explore
epithelial cell	9 studies	48% ± 22%	Explore
B cell	9 studies	38% ± 15%	Explore
myeloid cell	9 studies	48% ± 21%	Explore
mesothelial cell	9 studies	46% ± 19%	Explore
GABAergic neuron	8 studies	38% ± 16%	Explore
CD8-positive, alpha-beta T cell	8 studies	29% ± 11%	Explore
mast cell	8 studies	50% ± 10%	Explore
basal cell	8 studies	43% ± 26%	Explore
retinal cone cell	7 studies	64% ± 34%	Explore
glutamatergic neuron	6 studies	36% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	22% ± 5%	Explore
club cell	6 studies	53% ± 27%	Explore
dendritic cell	6 studies	38% ± 12%	Explore
monocyte	6 studies	52% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	33% ± 20%	Explore
interneuron	5 studies	38% ± 15%	Explore
neuron	5 studies	42% ± 24%	Explore
myofibroblast cell	5 studies	42% ± 22%	Explore
lymphocyte	5 studies	38% ± 17%	Explore
Mueller cell	5 studies	55% ± 23%	Explore
natural killer cell	5 studies	32% ± 9%	Explore
type I pneumocyte	5 studies	64% ± 11%	Explore
type II pneumocyte	5 studies	50% ± 13%	Explore
regulatory T cell	5 studies	38% ± 16%	Explore
classical monocyte	4 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	38% ± 18%	Explore
abnormal cell	4 studies	21% ± 6%	Explore
granule cell	4 studies	75% ± 9%	Explore
retinal rod cell	4 studies	46% ± 30%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 2%	Explore
alveolar macrophage	4 studies	68% ± 29%	Explore
leukocyte	4 studies	70% ± 14%	Explore
cholangiocyte	3 studies	62% ± 13%	Explore
hepatic stellate cell	3 studies	54% ± 19%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	79% ± 8%	Explore
glial cell	3 studies	39% ± 20%	Explore
progenitor cell	3 studies	34% ± 5%	Explore
OFF-bipolar cell	3 studies	59% ± 29%	Explore
ON-bipolar cell	3 studies	59% ± 27%	Explore
rod bipolar cell	3 studies	45% ± 14%	Explore
innate lymphoid cell	3 studies	35% ± 26%	Explore
endothelial cell of vascular tree	3 studies	41% ± 8%	Explore
mature NK T cell	3 studies	30% ± 16%	Explore
retinal pigment epithelial cell	3 studies	47% ± 22%	Explore
connective tissue cell	3 studies	40% ± 28%	Explore
ependymal cell	3 studies	79% ± 5%	Explore
capillary endothelial cell	3 studies	40% ± 5%	Explore
respiratory goblet cell	3 studies	65% ± 24%	Explore
T follicular helper cell	3 studies	23% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	69% ± 33%	Explore
mural cell	3 studies	59% ± 10%	Explore
mucus secreting cell	3 studies	59% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	16 studies	41% ± 12%	Explore
lung	8 studies	41% ± 19%	Explore
heart	6 studies	31% ± 12%	Explore
eye	5 studies	44% ± 8%	Explore
adipose	4 studies	50% ± 29%	Explore
peripheral blood	3 studies	21% ± 3%	Explore
kidney	3 studies	64% ± 10%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	99%	1576.73	178 / 180	97%	18.54	418 / 430
thymus	100%	2196.51	653 / 653	94%	16.82	568 / 605
brain	93%	919.81	2464 / 2642	100%	46.54	704 / 705
intestine	100%	1513.63	965 / 966	90%	10.54	472 / 527
kidney	100%	1631.27	89 / 89	89%	23.37	805 / 901
skin	100%	2998.64	1806 / 1809	89%	16.97	418 / 472
lung	100%	2751.26	577 / 578	88%	12.24	1017 / 1155
esophagus	99%	1427.82	1432 / 1445	89%	11.34	162 / 183
prostate	100%	1880.97	245 / 245	83%	9.50	419 / 502
breast	100%	3772.22	459 / 459	82%	12.16	921 / 1118
bladder	100%	2135.19	21 / 21	82%	9.23	412 / 504
stomach	93%	792.92	334 / 359	87%	11.71	250 / 286
uterus	100%	1511.38	170 / 170	73%	8.27	337 / 459
pancreas	70%	441.38	229 / 328	95%	15.42	169 / 178
adrenal gland	93%	791.74	240 / 258	60%	5.52	139 / 230
adipose	100%	3432.34	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2683.84	1335 / 1335	0%	0	0 / 0
spleen	100%	1808.16	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.13	1 / 1
heart	85%	782.99	731 / 861	0%	0	0 / 0
peripheral blood	73%	831.08	678 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	69%	5.85	31 / 45
eye	0%	0	0 / 0	68%	5.96	54 / 80
lymph node	0%	0	0 / 0	62%	5.06	18 / 29
muscle	44%	274.80	356 / 803	0%	0	0 / 0
liver	5%	26.19	12 / 226	17%	1.88	67 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0