LEPROTL1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
T cell	37 studies	40% ± 16%	Explore
CD8-positive, alpha-beta T cell	35 studies	46% ± 16%	Explore
natural killer cell	34 studies	34% ± 10%	Explore
CD4-positive, alpha-beta T cell	34 studies	53% ± 18%	Explore
regulatory T cell	27 studies	54% ± 14%	Explore
endothelial cell	21 studies	26% ± 12%	Explore
mature NK T cell	20 studies	37% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	58% ± 15%	Explore
mast cell	17 studies	29% ± 8%	Explore
gamma-delta T cell	17 studies	45% ± 15%	Explore
non-classical monocyte	17 studies	28% ± 13%	Explore
mucosal invariant T cell	16 studies	46% ± 13%	Explore
macrophage	15 studies	24% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	36% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	63% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	33% ± 11%	Explore
classical monocyte	13 studies	24% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	44% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	52% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	55% ± 15%	Explore
endothelial cell of artery	10 studies	28% ± 18%	Explore
monocyte	10 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	27% ± 8%	Explore
conventional dendritic cell	8 studies	32% ± 12%	Explore
capillary endothelial cell	8 studies	27% ± 14%	Explore
T follicular helper cell	8 studies	47% ± 19%	Explore
alveolar macrophage	7 studies	27% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	39% ± 3%	Explore
innate lymphoid cell	7 studies	37% ± 9%	Explore
CD4-positive helper T cell	6 studies	55% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	52% ± 10%	Explore
leukocyte	6 studies	33% ± 8%	Explore
myeloid cell	6 studies	25% ± 9%	Explore
epithelial cell	6 studies	38% ± 12%	Explore
ciliated cell	6 studies	33% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	58% ± 15%	Explore
hematopoietic precursor cell	5 studies	24% ± 10%	Explore
plasmablast	5 studies	38% ± 18%	Explore
exhausted T cell	5 studies	47% ± 8%	Explore
platelet	5 studies	19% ± 2%	Explore
lymphocyte	5 studies	33% ± 18%	Explore
dendritic cell	5 studies	34% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	32% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	47% ± 17%	Explore
mesothelial cell	4 studies	29% ± 16%	Explore
hematopoietic stem cell	4 studies	22% ± 6%	Explore
pericyte	4 studies	19% ± 2%	Explore
GABAergic neuron	4 studies	33% ± 8%	Explore
glutamatergic neuron	4 studies	37% ± 8%	Explore
enteroendocrine cell	4 studies	24% ± 6%	Explore
T-helper 17 cell	4 studies	49% ± 14%	Explore
double negative thymocyte	4 studies	51% ± 7%	Explore
pancreatic A cell	3 studies	27% ± 3%	Explore
mononuclear phagocyte	3 studies	34% ± 3%	Explore
B cell	3 studies	19% ± 3%	Explore
abnormal cell	3 studies	22% ± 1%	Explore
thymocyte	3 studies	25% ± 9%	Explore
fibroblast	3 studies	24% ± 7%	Explore
intraepithelial lymphocyte	3 studies	35% ± 15%	Explore
endothelial cell of vascular tree	3 studies	18% ± 2%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 4%	Explore
granulocyte	3 studies	43% ± 5%	Explore
neutrophil	3 studies	19% ± 1%	Explore
intestinal crypt stem cell	3 studies	18% ± 1%	Explore
group 3 innate lymphoid cell	3 studies	42% ± 10%	Explore
interneuron	3 studies	31% ± 13%	Explore
neuron	3 studies	31% ± 13%	Explore
oligodendrocyte	3 studies	18% ± 4%	Explore
T-helper 1 cell	3 studies	56% ± 14%	Explore
connective tissue cell	3 studies	19% ± 2%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	63% ± 4%	Explore
double-positive, alpha-beta thymocyte	3 studies	65% ± 12%	Explore
basal cell	3 studies	31% ± 7%	Explore
erythrocyte	3 studies	31% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	37% ± 9%	Explore
lung	13 studies	24% ± 7%	Explore
brain	7 studies	24% ± 9%	Explore
intestine	5 studies	26% ± 8%	Explore
liver	4 studies	34% ± 7%	Explore
pancreas	3 studies	26% ± 6%	Explore
kidney	3 studies	31% ± 9%	Explore
bone marrow	3 studies	26% ± 6%	Explore
uterus	3 studies	25% ± 7%	Explore
lymph node	3 studies	45% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2275.07	2642 / 2642	100%	45.50	705 / 705
esophagus	100%	1474.31	1445 / 1445	100%	25.56	183 / 183
lung	100%	2577.95	578 / 578	100%	28.59	1155 / 1155
ovary	100%	2219.51	180 / 180	100%	22.14	430 / 430
thymus	100%	1613.72	653 / 653	100%	35.13	604 / 605
breast	100%	2286.47	459 / 459	100%	34.10	1115 / 1118
kidney	100%	1839.38	89 / 89	100%	53.57	898 / 901
stomach	100%	1427.50	359 / 359	100%	29.59	285 / 286
prostate	100%	1611.35	245 / 245	100%	21.37	500 / 502
adrenal gland	100%	3694.59	258 / 258	100%	40.43	229 / 230
uterus	100%	2255.38	170 / 170	100%	24.14	457 / 459
skin	100%	1785.28	1807 / 1809	100%	42.51	470 / 472
intestine	100%	1975.94	966 / 966	99%	28.02	523 / 527
bladder	100%	1710.71	21 / 21	99%	24.59	500 / 504
pancreas	99%	931.87	324 / 328	99%	30.50	176 / 178
liver	100%	1216.58	226 / 226	97%	18.48	392 / 406
adipose	100%	2793.50	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	29.06	80 / 80
lymph node	0%	0	0 / 0	100%	29.37	29 / 29
spleen	100%	2627.35	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	22.32	45 / 45
ureter	0%	0	0 / 0	100%	11.09	1 / 1
heart	100%	2337.89	860 / 861	0%	0	0 / 0
blood vessel	100%	2111.52	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	2211.05	918 / 929	0%	0	0 / 0
muscle	96%	790.13	768 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0060400	Biological process	negative regulation of growth hormone receptor signaling pathway
GO_0032511	Biological process	late endosome to vacuole transport via multivesicular body sorting pathway
GO_0005768	Cellular component	endosome
GO_0016020	Cellular component	membrane
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	LEPROTL1
Protein name	Leptin receptor overlapping transcript-like 1 (Endospanin-2) Leptin receptor overlapping transcript-like 1
Synonyms	My047 UNQ577/PRO1139 TRG12 hCG_15463
Description	FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. . FUNCTION: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. .
Accessions	ENST00000321250.13 [O95214-1] C9JVM4 ENST00000523116.5 [O95214-2] A0A3B3IS19 ENST00000518192.5 ENST00000520682.5 E5RIQ0 ENST00000519466.1 Q6FHL7 O95214 ENST00000650149.1 ENST00000442880.6 ENST00000520739.5 E5RJS9 H0YBC1 E5RIL0 ENST00000518001.1 E5RHU8

LEPROTL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review