KLF3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	33 studies	27% ± 10%	Explore
natural killer cell	22 studies	28% ± 10%	Explore
macrophage	20 studies	25% ± 8%	Explore
non-classical monocyte	20 studies	41% ± 19%	Explore
CD4-positive, alpha-beta T cell	16 studies	29% ± 13%	Explore
fibroblast	15 studies	21% ± 4%	Explore
capillary endothelial cell	14 studies	23% ± 4%	Explore
monocyte	13 studies	23% ± 9%	Explore
classical monocyte	13 studies	28% ± 11%	Explore
endothelial cell of lymphatic vessel	12 studies	25% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	33% ± 11%	Explore
basal cell	12 studies	37% ± 21%	Explore
epithelial cell	12 studies	41% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	28% ± 13%	Explore
T cell	11 studies	22% ± 8%	Explore
mature NK T cell	11 studies	26% ± 7%	Explore
endothelial cell of artery	10 studies	25% ± 2%	Explore
CD8-positive, alpha-beta T cell	9 studies	34% ± 14%	Explore
plasmacytoid dendritic cell	9 studies	21% ± 3%	Explore
naive B cell	9 studies	25% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	24% ± 8%	Explore
goblet cell	9 studies	31% ± 16%	Explore
mucosal invariant T cell	9 studies	31% ± 12%	Explore
dendritic cell	8 studies	30% ± 17%	Explore
ciliated cell	8 studies	32% ± 21%	Explore
club cell	8 studies	30% ± 12%	Explore
secretory cell	8 studies	37% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	30% ± 13%	Explore
myeloid cell	8 studies	24% ± 8%	Explore
gamma-delta T cell	8 studies	36% ± 11%	Explore
respiratory goblet cell	7 studies	36% ± 9%	Explore
conventional dendritic cell	7 studies	29% ± 10%	Explore
regulatory T cell	7 studies	31% ± 12%	Explore
vein endothelial cell	7 studies	22% ± 7%	Explore
endothelial cell of vascular tree	7 studies	22% ± 7%	Explore
microglial cell	7 studies	26% ± 9%	Explore
oligodendrocyte	7 studies	26% ± 10%	Explore
B cell	6 studies	31% ± 8%	Explore
erythrocyte	6 studies	27% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	33% ± 14%	Explore
leukocyte	5 studies	22% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	40% ± 15%	Explore
memory B cell	5 studies	21% ± 2%	Explore
enterocyte	5 studies	19% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	32% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	34% ± 12%	Explore
squamous epithelial cell	4 studies	46% ± 18%	Explore
platelet	4 studies	21% ± 2%	Explore
myofibroblast cell	4 studies	21% ± 5%	Explore
hematopoietic stem cell	4 studies	20% ± 3%	Explore
lymphocyte	4 studies	21% ± 5%	Explore
brush cell	4 studies	24% ± 7%	Explore
mesothelial cell	4 studies	19% ± 4%	Explore
GABAergic neuron	4 studies	26% ± 7%	Explore
oligodendrocyte precursor cell	4 studies	28% ± 9%	Explore
connective tissue cell	4 studies	21% ± 2%	Explore
keratinocyte	4 studies	27% ± 3%	Explore
hillock cell	3 studies	25% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	21% ± 3%	Explore
plasmablast	3 studies	26% ± 6%	Explore
glomerular endothelial cell	3 studies	31% ± 4%	Explore
pericyte	3 studies	17% ± 1%	Explore
intermediate monocyte	3 studies	47% ± 21%	Explore
innate lymphoid cell	3 studies	24% ± 3%	Explore
granulocyte	3 studies	23% ± 8%	Explore
type I pneumocyte	3 studies	20% ± 4%	Explore
glutamatergic neuron	3 studies	24% ± 6%	Explore
pancreatic ductal cell	3 studies	38% ± 12%	Explore
abnormal cell	3 studies	23% ± 5%	Explore
enteroendocrine cell	3 studies	22% ± 4%	Explore
intestinal crypt stem cell	3 studies	20% ± 5%	Explore
transit amplifying cell	3 studies	37% ± 29%	Explore
astrocyte	3 studies	19% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	28% ± 11%	Explore
lung	8 studies	31% ± 20%	Explore
brain	6 studies	27% ± 8%	Explore
intestine	4 studies	24% ± 6%	Explore
bone marrow	3 studies	27% ± 4%	Explore
uterus	3 studies	25% ± 11%	Explore
adipose	3 studies	20% ± 4%	Explore
liver	3 studies	35% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6305.86	1445 / 1445	100%	74.81	183 / 183
ovary	100%	8742.32	180 / 180	100%	29.32	430 / 430
prostate	100%	4929.17	245 / 245	100%	51.41	502 / 502
lung	100%	5168.50	578 / 578	100%	47.80	1154 / 1155
intestine	100%	5650.43	966 / 966	99%	61.01	524 / 527
bladder	100%	5139.19	21 / 21	99%	48.68	501 / 504
breast	100%	4736.12	459 / 459	99%	35.48	1110 / 1118
uterus	100%	4824.19	170 / 170	99%	48.05	455 / 459
stomach	100%	4393.46	359 / 359	99%	62.41	283 / 286
thymus	100%	4438.85	653 / 653	98%	36.49	595 / 605
liver	100%	2950.19	225 / 226	98%	25.72	398 / 406
pancreas	97%	2811.31	319 / 328	99%	48.28	177 / 178
kidney	100%	2790.18	89 / 89	97%	28.13	871 / 901
brain	97%	1974.90	2564 / 2642	100%	34.67	702 / 705
adrenal gland	100%	3538.53	258 / 258	95%	23.74	219 / 230
skin	100%	9258.59	1809 / 1809	95%	22.72	448 / 472
adipose	100%	5534.56	1204 / 1204	0%	0	0 / 0
spleen	100%	4333.31	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	59.27	45 / 45
ureter	0%	0	0 / 0	100%	24.18	1 / 1
blood vessel	100%	3956.63	1330 / 1335	0%	0	0 / 0
heart	97%	2034.52	832 / 861	0%	0	0 / 0
peripheral blood	95%	3817.89	887 / 929	0%	0	0 / 0
muscle	90%	1776.40	722 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	88%	15.50	70 / 80
lymph node	0%	0	0 / 0	48%	7.09	14 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1901653	Biological process	cellular response to peptide
GO_0030097	Biological process	hemopoiesis
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	KLF3
Protein name	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Synonyms	BKLF
Description	FUNCTION: Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis (By similarity). .
Accessions	P57682 ENST00000261438.10 [P57682-1] ENST00000514033.1 [P57682-2]

KLF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review