HDGF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006338Biological processchromatin remodeling
GO_0034504Biological processprotein localization to nucleus
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005654Cellular componentnucleoplasm
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0017053Cellular componenttranscription repressor complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0008201Molecular functionheparin binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0003714Molecular functiontranscription corepressor activity
GO_0001222Molecular functiontranscription corepressor binding
GO_0008083Molecular functiongrowth factor activity
GO_0000166Molecular functionnucleotide binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameHDGF
Protein nameHepatoma-derived growth factor 4a
Heparin binding growth factor
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Hepatoma-derived growth factor 4b
SynonymsHMG1L2
DescriptionFUNCTION: [Isoform 1]: Acts as a transcriptional repressor . Has mitogenic activity for fibroblasts . Heparin-binding protein . .; FUNCTION: [Isoform 2]: Does not have mitogenic activity for fibroblasts . Does not bind heparin . .; FUNCTION: [Isoform 3]: Has mitogenic activity for fibroblasts . Heparin-binding protein . .

AccessionsQ7Z4S4
P51858
ENST00000710272.1
ENST00000368209.9 [P51858-2]
A0AA34QVG5
ENST00000368206.5 [P51858-3]
ENST00000357325.10 [P51858-1]
Q7Z4S5