EPB41 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	27% ± 8%	Explore
regulatory T cell	23 studies	34% ± 10%	Explore
CD8-positive, alpha-beta T cell	22 studies	27% ± 8%	Explore
B cell	21 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	20 studies	33% ± 8%	Explore
T cell	19 studies	30% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	34% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	30% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	27% ± 6%	Explore
naive B cell	14 studies	21% ± 4%	Explore
mucosal invariant T cell	14 studies	28% ± 8%	Explore
gamma-delta T cell	14 studies	28% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	27% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	31% ± 8%	Explore
memory B cell	13 studies	23% ± 3%	Explore
erythrocyte	12 studies	50% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	33% ± 10%	Explore
mature NK T cell	11 studies	26% ± 8%	Explore
microglial cell	11 studies	36% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	29% ± 7%	Explore
endothelial cell	10 studies	33% ± 12%	Explore
glutamatergic neuron	9 studies	49% ± 21%	Explore
adipocyte	9 studies	40% ± 10%	Explore
platelet	8 studies	20% ± 5%	Explore
retinal rod cell	8 studies	54% ± 27%	Explore
epithelial cell	8 studies	32% ± 19%	Explore
macrophage	7 studies	28% ± 10%	Explore
retinal cone cell	7 studies	65% ± 19%	Explore
neuron	6 studies	39% ± 21%	Explore
GABAergic neuron	6 studies	41% ± 19%	Explore
interneuron	6 studies	32% ± 12%	Explore
amacrine cell	6 studies	33% ± 13%	Explore
retinal ganglion cell	6 studies	50% ± 23%	Explore
T follicular helper cell	6 studies	27% ± 8%	Explore
type II pneumocyte	6 studies	35% ± 7%	Explore
dendritic cell	6 studies	27% ± 12%	Explore
plasmablast	5 studies	23% ± 8%	Explore
retinal bipolar neuron	5 studies	52% ± 19%	Explore
cardiac muscle cell	5 studies	36% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	34% ± 10%	Explore
astrocyte	5 studies	33% ± 16%	Explore
type I pneumocyte	5 studies	32% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	29% ± 10%	Explore
CD4-positive helper T cell	4 studies	22% ± 3%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	29% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	23% ± 4%	Explore
leukocyte	4 studies	43% ± 9%	Explore
mesothelial cell	4 studies	21% ± 5%	Explore
lymphocyte	4 studies	44% ± 17%	Explore
OFF-bipolar cell	4 studies	69% ± 20%	Explore
ON-bipolar cell	4 studies	58% ± 11%	Explore
innate lymphoid cell	4 studies	25% ± 6%	Explore
monocyte	4 studies	27% ± 2%	Explore
club cell	4 studies	28% ± 6%	Explore
endothelial cell of lymphatic vessel	4 studies	25% ± 6%	Explore
double negative thymocyte	4 studies	33% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	30% ± 2%	Explore
granule cell	3 studies	57% ± 21%	Explore
plasma cell	3 studies	36% ± 6%	Explore
myeloid cell	3 studies	21% ± 5%	Explore
GABAergic amacrine cell	3 studies	38% ± 10%	Explore
Mueller cell	3 studies	30% ± 9%	Explore
glycinergic amacrine cell	3 studies	48% ± 7%	Explore
retina horizontal cell	3 studies	29% ± 7%	Explore
rod bipolar cell	3 studies	63% ± 8%	Explore
hepatocyte	3 studies	64% ± 20%	Explore
alveolar macrophage	3 studies	26% ± 5%	Explore
respiratory goblet cell	3 studies	28% ± 13%	Explore
group 3 innate lymphoid cell	3 studies	25% ± 6%	Explore
basal cell	3 studies	37% ± 21%	Explore
goblet cell	3 studies	38% ± 26%	Explore
transit amplifying cell	3 studies	38% ± 25%	Explore
T-helper 17 cell	3 studies	19% ± 3%	Explore
plasmacytoid dendritic cell	3 studies	20% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	35% ± 2%	Explore
abnormal cell	3 studies	34% ± 11%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	25% ± 6%	Explore
brain	10 studies	34% ± 17%	Explore
eye	9 studies	46% ± 20%	Explore
lung	6 studies	22% ± 6%	Explore
liver	5 studies	33% ± 14%	Explore
bone marrow	4 studies	20% ± 3%	Explore
heart	4 studies	19% ± 4%	Explore
adipose	4 studies	22% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2114.02	1441 / 1445	99%	10.37	182 / 183
intestine	100%	3241.74	965 / 966	99%	10.49	521 / 527
lung	100%	3079.45	576 / 578	99%	9.56	1141 / 1155
breast	100%	2484.27	459 / 459	97%	11.02	1084 / 1118
prostate	100%	2527.20	244 / 245	97%	12.38	487 / 502
bladder	100%	2468.48	21 / 21	96%	9.33	486 / 504
kidney	100%	2422.97	89 / 89	96%	8.91	865 / 901
stomach	96%	2713.21	345 / 359	99%	11.25	284 / 286
pancreas	100%	2455.55	328 / 328	94%	6.59	168 / 178
thymus	100%	2810.60	652 / 653	94%	7.02	567 / 605
ovary	100%	2774.47	180 / 180	91%	6.43	390 / 430
uterus	100%	2639.70	170 / 170	90%	6.86	413 / 459
liver	100%	3298.25	226 / 226	85%	5.76	344 / 406
adrenal gland	100%	2585.46	257 / 258	79%	6.05	181 / 230
skin	80%	2770.79	1454 / 1809	91%	7.73	428 / 472
brain	81%	4481.18	2128 / 2642	87%	5.25	614 / 705
muscle	100%	2349.90	803 / 803	0%	0	0 / 0
spleen	100%	4182.59	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.62	1 / 1
peripheral blood	100%	5731.51	928 / 929	0%	0	0 / 0
adipose	100%	2327.76	1202 / 1204	0%	0	0 / 0
blood vessel	98%	1266.37	1309 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	6.83	41 / 45
heart	90%	1425.69	775 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	11.40	26 / 29
eye	0%	0	0 / 0	70%	3.40	56 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0