DPY30 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
ciliated cell	17 studies	65% ± 18%	Explore
epithelial cell	15 studies	38% ± 21%	Explore
CD4-positive, alpha-beta T cell	13 studies	19% ± 3%	Explore
endothelial cell	13 studies	28% ± 11%	Explore
fibroblast	13 studies	24% ± 9%	Explore
smooth muscle cell	12 studies	22% ± 6%	Explore
regulatory T cell	12 studies	19% ± 3%	Explore
natural killer cell	11 studies	21% ± 5%	Explore
CD8-positive, alpha-beta T cell	11 studies	19% ± 2%	Explore
T cell	10 studies	23% ± 10%	Explore
basal cell	9 studies	34% ± 19%	Explore
B cell	9 studies	22% ± 8%	Explore
pericyte	8 studies	24% ± 8%	Explore
abnormal cell	8 studies	28% ± 8%	Explore
epithelial cell of proximal tubule	7 studies	31% ± 10%	Explore
connective tissue cell	7 studies	27% ± 10%	Explore
macrophage	7 studies	26% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
kidney loop of Henle epithelial cell	6 studies	27% ± 4%	Explore
myofibroblast cell	6 studies	23% ± 4%	Explore
progenitor cell	6 studies	32% ± 8%	Explore
goblet cell	6 studies	28% ± 16%	Explore
neuron	6 studies	31% ± 17%	Explore
non-classical monocyte	5 studies	24% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 2%	Explore
classical monocyte	5 studies	22% ± 6%	Explore
conventional dendritic cell	5 studies	26% ± 9%	Explore
enterocyte	5 studies	22% ± 6%	Explore
enteroendocrine cell	5 studies	37% ± 16%	Explore
memory B cell	5 studies	17% ± 2%	Explore
type II pneumocyte	5 studies	30% ± 18%	Explore
astrocyte	5 studies	30% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	19% ± 5%	Explore
oligodendrocyte precursor cell	5 studies	23% ± 5%	Explore
deuterosomal cell	4 studies	36% ± 11%	Explore
pancreatic A cell	4 studies	37% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	17% ± 1%	Explore
intestinal crypt stem cell	4 studies	25% ± 4%	Explore
type I pneumocyte	4 studies	32% ± 12%	Explore
innate lymphoid cell	4 studies	17% ± 3%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	25% ± 5%	Explore
endothelial cell of vascular tree	4 studies	19% ± 2%	Explore
GABAergic neuron	4 studies	41% ± 21%	Explore
glutamatergic neuron	4 studies	50% ± 21%	Explore
dendritic cell	4 studies	29% ± 11%	Explore
oligodendrocyte	4 studies	28% ± 13%	Explore
plasmacytoid dendritic cell	4 studies	22% ± 6%	Explore
gamma-delta T cell	4 studies	27% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	19% ± 3%	Explore
type B pancreatic cell	3 studies	44% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
hematopoietic precursor cell	3 studies	31% ± 13%	Explore
mature NK T cell	3 studies	19% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	44% ± 14%	Explore
renal alpha-intercalated cell	3 studies	29% ± 2%	Explore
endothelial cell of artery	3 studies	20% ± 4%	Explore
mesothelial cell	3 studies	34% ± 19%	Explore
naive B cell	3 studies	19% ± 4%	Explore
retinal ganglion cell	3 studies	45% ± 25%	Explore
myeloid cell	3 studies	26% ± 12%	Explore
plasma cell	3 studies	34% ± 11%	Explore
club cell	3 studies	35% ± 6%	Explore
neuroendocrine cell	3 studies	28% ± 6%	Explore
pro-B cell	3 studies	22% ± 5%	Explore
erythroblast	3 studies	35% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
endothelial cell of lymphatic vessel	3 studies	29% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	32% ± 17%	Explore
transit amplifying cell	3 studies	19% ± 2%	Explore
secretory cell	3 studies	40% ± 21%	Explore
T follicular helper cell	3 studies	17% ± 1%	Explore
T-helper 17 cell	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	30% ± 14%	Explore
kidney	8 studies	22% ± 4%	Explore
peripheral blood	7 studies	20% ± 3%	Explore
intestine	6 studies	25% ± 12%	Explore
brain	6 studies	34% ± 20%	Explore
liver	5 studies	26% ± 17%	Explore
pancreas	3 studies	42% ± 1%	Explore
eye	3 studies	24% ± 7%	Explore
thymus	3 studies	37% ± 14%	Explore
lymph node	3 studies	28% ± 10%	Explore
breast	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1403.03	2642 / 2642	100%	41.00	705 / 705
esophagus	100%	1292.16	1445 / 1445	100%	40.22	183 / 183
liver	100%	793.24	226 / 226	100%	34.64	406 / 406
ovary	100%	1194.72	180 / 180	100%	78.29	430 / 430
stomach	100%	1034.52	359 / 359	100%	41.61	286 / 286
uterus	100%	1155.71	170 / 170	100%	64.37	459 / 459
thymus	100%	1698.71	653 / 653	100%	60.85	604 / 605
intestine	100%	1296.20	966 / 966	100%	43.64	526 / 527
prostate	100%	1564.83	245 / 245	100%	56.14	501 / 502
kidney	100%	1543.79	89 / 89	100%	39.11	899 / 901
breast	100%	1256.39	459 / 459	100%	55.50	1114 / 1118
bladder	100%	1253.57	21 / 21	100%	51.79	502 / 504
lung	99%	1064.47	575 / 578	100%	55.79	1155 / 1155
adrenal gland	100%	2003.10	258 / 258	99%	38.80	228 / 230
skin	100%	1341.16	1808 / 1809	99%	30.62	467 / 472
pancreas	99%	674.31	326 / 328	99%	38.88	177 / 178
adipose	100%	1116.66	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	43.42	29 / 29
spleen	100%	981.13	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.74	45 / 45
ureter	0%	0	0 / 0	100%	20.56	1 / 1
blood vessel	100%	1315.95	1334 / 1335	0%	0	0 / 0
muscle	100%	825.68	801 / 803	0%	0	0 / 0
heart	98%	783.23	844 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	22.27	76 / 80
peripheral blood	83%	719.41	768 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0016197	Biological process	endosomal transport
GO_0045815	Biological process	transcription initiation-coupled chromatin remodeling
GO_0005802	Cellular component	trans-Golgi network
GO_0048188	Cellular component	Set1C/COMPASS complex
GO_0044665	Cellular component	MLL1/2 complex
GO_0035097	Cellular component	histone methyltransferase complex
GO_0005654	Cellular component	nucleoplasm
GO_0071339	Cellular component	MLL1 complex
GO_0005794	Cellular component	Golgi apparatus
GO_0044666	Cellular component	MLL3/4 complex
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	DPY30
Protein name	Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)
Synonyms
Description	FUNCTION: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. .
Accessions	Q9C005 ENST00000295066.3 ENST00000342166.10

DPY30 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review