DCAF7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	20 studies	21% ± 4%	Explore
endothelial cell	17 studies	26% ± 10%	Explore
macrophage	14 studies	23% ± 7%	Explore
B cell	12 studies	19% ± 4%	Explore
CD8-positive, alpha-beta T cell	11 studies	20% ± 3%	Explore
T cell	10 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	20% ± 4%	Explore
conventional dendritic cell	9 studies	25% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	19% ± 3%	Explore
non-classical monocyte	8 studies	21% ± 7%	Explore
fibroblast	8 studies	21% ± 3%	Explore
regulatory T cell	8 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	8 studies	23% ± 8%	Explore
gamma-delta T cell	8 studies	23% ± 13%	Explore
basal cell	7 studies	25% ± 9%	Explore
pericyte	7 studies	20% ± 3%	Explore
epithelial cell	7 studies	34% ± 13%	Explore
ciliated cell	7 studies	23% ± 8%	Explore
endothelial cell of lymphatic vessel	7 studies	21% ± 3%	Explore
memory B cell	7 studies	17% ± 1%	Explore
CD4-positive, alpha-beta T cell	7 studies	20% ± 5%	Explore
oligodendrocyte	7 studies	23% ± 5%	Explore
plasmacytoid dendritic cell	7 studies	22% ± 6%	Explore
glutamatergic neuron	6 studies	43% ± 21%	Explore
microglial cell	6 studies	25% ± 7%	Explore
precursor B cell	6 studies	32% ± 13%	Explore
neuron	6 studies	34% ± 10%	Explore
naive B cell	6 studies	19% ± 3%	Explore
GABAergic neuron	6 studies	36% ± 18%	Explore
interneuron	6 studies	30% ± 17%	Explore
hematopoietic precursor cell	5 studies	29% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	19% ± 4%	Explore
classical monocyte	5 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
pro-B cell	5 studies	30% ± 7%	Explore
myofibroblast cell	5 studies	21% ± 2%	Explore
myeloid cell	5 studies	24% ± 8%	Explore
type I pneumocyte	5 studies	20% ± 2%	Explore
retinal cone cell	5 studies	28% ± 9%	Explore
astrocyte	5 studies	27% ± 5%	Explore
dendritic cell	5 studies	30% ± 15%	Explore
goblet cell	5 studies	29% ± 8%	Explore
mature NK T cell	5 studies	19% ± 3%	Explore
secretory cell	4 studies	20% ± 2%	Explore
progenitor cell	4 studies	19% ± 2%	Explore
hematopoietic stem cell	4 studies	23% ± 5%	Explore
lymphocyte	4 studies	24% ± 3%	Explore
smooth muscle cell	4 studies	17% ± 2%	Explore
club cell	4 studies	24% ± 5%	Explore
immature B cell	4 studies	18% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	22% ± 3%	Explore
abnormal cell	4 studies	24% ± 11%	Explore
monocyte	4 studies	25% ± 5%	Explore
enteroendocrine cell	4 studies	29% ± 10%	Explore
alveolar macrophage	4 studies	28% ± 9%	Explore
mast cell	4 studies	22% ± 7%	Explore
mucosal invariant T cell	4 studies	17% ± 1%	Explore
respiratory goblet cell	3 studies	24% ± 10%	Explore
pancreatic A cell	3 studies	36% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
connective tissue cell	3 studies	22% ± 1%	Explore
glial cell	3 studies	25% ± 11%	Explore
brush cell	3 studies	32% ± 3%	Explore
capillary endothelial cell	3 studies	28% ± 9%	Explore
retina horizontal cell	3 studies	21% ± 6%	Explore
retinal rod cell	3 studies	21% ± 2%	Explore
mononuclear phagocyte	3 studies	24% ± 11%	Explore
rod bipolar cell	3 studies	22% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	20% ± 1%	Explore
exhausted T cell	3 studies	18% ± 1%	Explore
type II pneumocyte	3 studies	20% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
transit amplifying cell	3 studies	27% ± 9%	Explore
hepatocyte	3 studies	34% ± 13%	Explore
double negative thymocyte	3 studies	28% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	21% ± 3%	Explore
brain	8 studies	33% ± 15%	Explore
peripheral blood	7 studies	20% ± 5%	Explore
kidney	4 studies	17% ± 1%	Explore
eye	4 studies	22% ± 4%	Explore
bone marrow	3 studies	18% ± 3%	Explore
intestine	3 studies	24% ± 8%	Explore
adipose	3 studies	17% ± 1%	Explore
liver	3 studies	35% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4543.98	2642 / 2642	100%	109.82	705 / 705
esophagus	100%	4596.33	1445 / 1445	100%	80.53	183 / 183
ovary	100%	4065.48	180 / 180	100%	66.32	430 / 430
prostate	100%	4854.84	245 / 245	100%	83.73	502 / 502
stomach	100%	3822.62	359 / 359	100%	76.71	286 / 286
lung	100%	5583.73	578 / 578	100%	78.01	1154 / 1155
intestine	100%	5282.39	966 / 966	100%	77.01	526 / 527
bladder	100%	4954.62	21 / 21	100%	72.27	503 / 504
breast	100%	4351.16	459 / 459	100%	91.15	1115 / 1118
skin	100%	4549.81	1809 / 1809	100%	98.74	470 / 472
thymus	100%	4946.22	653 / 653	99%	65.63	601 / 605
uterus	100%	4798.75	170 / 170	99%	64.14	455 / 459
kidney	100%	4389.54	89 / 89	98%	67.66	884 / 901
pancreas	100%	2743.39	327 / 328	98%	56.50	175 / 178
adrenal gland	100%	4373.50	258 / 258	95%	48.09	219 / 230
liver	100%	2220.69	226 / 226	86%	29.13	351 / 406
adipose	100%	4221.78	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3928.66	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	63.84	80 / 80
lymph node	0%	0	0 / 0	100%	69.94	29 / 29
spleen	100%	6034.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	74.06	45 / 45
ureter	0%	0	0 / 0	100%	28.55	1 / 1
muscle	100%	2302.26	801 / 803	0%	0	0 / 0
heart	99%	3024.74	850 / 861	0%	0	0 / 0
peripheral blood	95%	4666.38	879 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0016567	Biological process	protein ubiquitination
GO_0016363	Cellular component	nuclear matrix
GO_0032991	Cellular component	protein-containing complex
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0080008	Cellular component	Cul4-RING E3 ubiquitin ligase complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0030674	Molecular function	protein-macromolecule adaptor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	DCAF7
Protein name	DDB1 and CUL4 associated factor 7 DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Synonyms	HAN11 WDR68
Description	FUNCTION: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. .
Accessions	A0A8I5KX45 A0A087WWI6 ENST00000415273.2 [P61962-2] A0A8I5KT41 ENST00000582274.2 ENST00000690481.1 ENST00000686787.1 ENST00000686337.1 [P61962-1] ENST00000614556.5 [P61962-1] A0A8I5KQ63 ENST00000692877.1 ENST00000615512.2 ENST00000690417.1 [P61962-1] ENST00000688888.1 ENST00000688437.1 ENST00000580091.2 A0A8I5KRG1 A0A8I5KTU5 P61962 A0A8I5KXF0 ENST00000691063.1 A0A8I5QKQ1 ENST00000693226.1 ENST00000431926.7 [P61962-1] A0A8I5KY66

DCAF7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review