CRLF3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	13 studies	21% ± 6%	Explore
B cell	12 studies	19% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	21% ± 4%	Explore
astrocyte	11 studies	29% ± 13%	Explore
regulatory T cell	11 studies	19% ± 4%	Explore
microglial cell	10 studies	29% ± 12%	Explore
T cell	9 studies	22% ± 4%	Explore
GABAergic neuron	9 studies	48% ± 22%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 4%	Explore
endothelial cell	9 studies	26% ± 9%	Explore
natural killer cell	8 studies	18% ± 3%	Explore
glutamatergic neuron	8 studies	54% ± 26%	Explore
oligodendrocyte	7 studies	29% ± 8%	Explore
oligodendrocyte precursor cell	7 studies	35% ± 12%	Explore
CD8-positive, alpha-beta T cell	7 studies	20% ± 7%	Explore
adipocyte	7 studies	22% ± 6%	Explore
macrophage	7 studies	30% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	17% ± 3%	Explore
dendritic cell	6 studies	26% ± 3%	Explore
fibroblast	6 studies	23% ± 6%	Explore
myeloid cell	5 studies	22% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	18% ± 3%	Explore
monocyte	5 studies	25% ± 7%	Explore
interneuron	5 studies	58% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	19% ± 3%	Explore
lymphocyte	4 studies	29% ± 11%	Explore
Mueller cell	4 studies	20% ± 2%	Explore
amacrine cell	4 studies	37% ± 14%	Explore
retinal rod cell	4 studies	32% ± 9%	Explore
endothelial cell of lymphatic vessel	4 studies	18% ± 1%	Explore
pericyte	4 studies	17% ± 1%	Explore
naive B cell	4 studies	19% ± 2%	Explore
smooth muscle cell	4 studies	18% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	21% ± 4%	Explore
classical monocyte	3 studies	20% ± 2%	Explore
neuron	3 studies	44% ± 21%	Explore
epithelial cell	3 studies	24% ± 6%	Explore
cardiac muscle cell	3 studies	21% ± 5%	Explore
GABAergic amacrine cell	3 studies	29% ± 7%	Explore
glycinergic amacrine cell	3 studies	28% ± 8%	Explore
retina horizontal cell	3 studies	29% ± 4%	Explore
retinal cone cell	3 studies	26% ± 3%	Explore
T follicular helper cell	3 studies	18% ± 2%	Explore
non-classical monocyte	3 studies	22% ± 6%	Explore
club cell	3 studies	19% ± 2%	Explore
alveolar macrophage	3 studies	23% ± 5%	Explore
type I pneumocyte	3 studies	19% ± 1%	Explore
type II pneumocyte	3 studies	20% ± 0%	Explore
mast cell	3 studies	20% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore
double negative thymocyte	3 studies	18% ± 1%	Explore
gamma-delta T cell	3 studies	21% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	11 studies	42% ± 22%	Explore
peripheral blood	7 studies	18% ± 3%	Explore
eye	5 studies	29% ± 8%	Explore
lung	4 studies	20% ± 3%	Explore
adipose	3 studies	22% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	913.69	1445 / 1445	100%	17.37	183 / 183
lung	100%	1087.72	578 / 578	100%	15.53	1155 / 1155
ovary	100%	603.43	180 / 180	100%	8.83	430 / 430
breast	100%	830.30	459 / 459	100%	13.14	1117 / 1118
intestine	100%	838.27	966 / 966	100%	12.16	526 / 527
stomach	100%	481.88	358 / 359	100%	12.27	286 / 286
bladder	100%	741.00	21 / 21	99%	12.60	501 / 504
prostate	100%	693.47	245 / 245	99%	7.33	498 / 502
thymus	100%	681.55	652 / 653	99%	10.01	601 / 605
brain	99%	632.18	2617 / 2642	100%	9.21	705 / 705
uterus	100%	778.16	170 / 170	99%	12.97	454 / 459
skin	100%	976.65	1808 / 1809	96%	10.73	454 / 472
kidney	100%	503.10	89 / 89	96%	9.48	861 / 901
adrenal gland	100%	486.88	258 / 258	95%	4.82	218 / 230
pancreas	96%	332.07	316 / 328	98%	10.85	175 / 178
liver	98%	313.07	222 / 226	83%	4.23	338 / 406
adipose	100%	865.27	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	26.42	29 / 29
spleen	100%	2200.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	14.44	45 / 45
ureter	0%	0	0 / 0	100%	5.87	1 / 1
blood vessel	100%	676.74	1332 / 1335	0%	0	0 / 0
peripheral blood	100%	2063.36	925 / 929	0%	0	0 / 0
heart	96%	346.45	830 / 861	0%	0	0 / 0
muscle	79%	206.84	636 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	76%	4.25	61 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_2000134	Biological process	negative regulation of G1/S transition of mitotic cell cycle
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0046427	Biological process	positive regulation of receptor signaling pathway via JAK-STAT
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0030308	Biological process	negative regulation of cell growth
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CRLF3
Protein name	Alternative protein CRLF3 Cytokine receptor-like factor 3 (Cytokine receptor-like molecule 9) (CREME-9) (Cytokine receptor-related protein 4) (Type I cytokine receptor-like factor p48) Cytokine receptor like factor 3
Synonyms	P48 CRLM9 CREME9 CYTOR4
Description	FUNCTION: May play a role in the negative regulation of cell cycle progression. .
Accessions	ENST00000583527.1 ENST00000578692.1 Q8IUI8 J3KST8 L8E8Q9 ENST00000324238.7 [Q8IUI8-1] J3QLS9

CRLF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review