COX16 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
regulatory T cell	15 studies	24% ± 5%	Explore
natural killer cell	14 studies	24% ± 8%	Explore
classical monocyte	12 studies	23% ± 6%	Explore
naive B cell	12 studies	21% ± 3%	Explore
plasmacytoid dendritic cell	12 studies	28% ± 8%	Explore
B cell	12 studies	25% ± 9%	Explore
CD4-positive, alpha-beta T cell	11 studies	23% ± 8%	Explore
CD8-positive, alpha-beta T cell	11 studies	28% ± 9%	Explore
macrophage	11 studies	22% ± 4%	Explore
conventional dendritic cell	10 studies	25% ± 13%	Explore
memory B cell	10 studies	22% ± 3%	Explore
endothelial cell	10 studies	25% ± 15%	Explore
fibroblast	9 studies	21% ± 4%	Explore
plasma cell	8 studies	26% ± 6%	Explore
ciliated cell	8 studies	29% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	23% ± 4%	Explore
non-classical monocyte	8 studies	27% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	25% ± 3%	Explore
mucosal invariant T cell	8 studies	21% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	24% ± 3%	Explore
gamma-delta T cell	8 studies	22% ± 4%	Explore
epithelial cell	7 studies	39% ± 22%	Explore
endothelial cell of lymphatic vessel	7 studies	26% ± 5%	Explore
secretory cell	6 studies	24% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	25% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	23% ± 12%	Explore
mature NK T cell	6 studies	21% ± 3%	Explore
plasmablast	5 studies	41% ± 24%	Explore
basal cell	5 studies	35% ± 23%	Explore
dendritic cell	5 studies	25% ± 7%	Explore
abnormal cell	5 studies	23% ± 11%	Explore
connective tissue cell	5 studies	25% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	25% ± 8%	Explore
precursor B cell	4 studies	25% ± 4%	Explore
T follicular helper cell	4 studies	22% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	24% ± 3%	Explore
neuron	4 studies	32% ± 23%	Explore
oligodendrocyte precursor cell	4 studies	25% ± 9%	Explore
goblet cell	4 studies	34% ± 17%	Explore
T cell	4 studies	20% ± 5%	Explore
kidney loop of Henle epithelial cell	3 studies	24% ± 8%	Explore
common myeloid progenitor	3 studies	33% ± 15%	Explore
erythroblast	3 studies	32% ± 16%	Explore
capillary endothelial cell	3 studies	25% ± 7%	Explore
myofibroblast cell	3 studies	17% ± 1%	Explore
pericyte	3 studies	23% ± 11%	Explore
exhausted T cell	3 studies	30% ± 7%	Explore
astrocyte	3 studies	26% ± 9%	Explore
innate lymphoid cell	3 studies	22% ± 2%	Explore
monocyte	3 studies	27% ± 4%	Explore
enteroendocrine cell	3 studies	38% ± 20%	Explore
intestinal crypt stem cell	3 studies	29% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	17% ± 2%	Explore
keratinocyte	3 studies	17% ± 1%	Explore
mononuclear phagocyte	3 studies	34% ± 16%	Explore
double negative thymocyte	3 studies	26% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	23% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	19% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	23% ± 3%	Explore
lung	6 studies	24% ± 11%	Explore
brain	5 studies	27% ± 14%	Explore
intestine	4 studies	28% ± 16%	Explore
kidney	3 studies	21% ± 1%	Explore
liver	3 studies	32% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1332.43	328 / 328	100%	6.75	178 / 178
prostate	100%	1729.75	245 / 245	100%	17.77	502 / 502
thymus	100%	1815.91	653 / 653	100%	12.12	605 / 605
brain	100%	1535.30	2641 / 2642	100%	9.17	705 / 705
adrenal gland	100%	2230.81	258 / 258	100%	9.25	229 / 230
kidney	100%	2098.31	89 / 89	99%	7.98	895 / 901
stomach	100%	1763.01	359 / 359	99%	6.48	284 / 286
intestine	100%	1458.05	966 / 966	99%	6.43	520 / 527
ovary	100%	1394.03	180 / 180	98%	7.11	423 / 430
esophagus	100%	1311.61	1445 / 1445	98%	6.20	179 / 183
breast	100%	1684.79	459 / 459	97%	9.37	1088 / 1118
bladder	100%	1366.43	21 / 21	97%	5.78	490 / 504
uterus	100%	1244.62	170 / 170	97%	5.80	445 / 459
lung	100%	1415.24	576 / 578	95%	5.30	1092 / 1155
skin	100%	1886.45	1809 / 1809	93%	4.30	437 / 472
liver	100%	1318.57	226 / 226	68%	2.77	277 / 406
adipose	100%	1482.29	1204 / 1204	0%	0	0 / 0
muscle	100%	2033.52	803 / 803	0%	0	0 / 0
spleen	100%	1491.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4.82	45 / 45
ureter	0%	0	0 / 0	100%	7.72	1 / 1
blood vessel	100%	1178.64	1331 / 1335	0%	0	0 / 0
heart	99%	1374.49	850 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	4.91	77 / 80
lymph node	0%	0	0 / 0	90%	3.43	26 / 29
peripheral blood	51%	741.01	471 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0033617	Biological process	mitochondrial cytochrome c oxidase assembly
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0003674	Molecular function	molecular_function
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	COX16
Protein name	Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (hCOX16)
Synonyms	PTD019 HSPC203 C14orf112
Description	FUNCTION: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase . Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) . Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6 . Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines . .
Accessions	Q9P0S2 ENST00000389912.7 ENST00000555276.5 A0A087WX56

COX16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review