CNTRL report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	33 studies	25% ± 7%	Explore
ciliated cell	18 studies	39% ± 12%	Explore
memory B cell	18 studies	21% ± 5%	Explore
naive B cell	15 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	13 studies	20% ± 2%	Explore
regulatory T cell	13 studies	19% ± 3%	Explore
CD4-positive, alpha-beta T cell	12 studies	20% ± 3%	Explore
macrophage	12 studies	28% ± 13%	Explore
natural killer cell	11 studies	20% ± 3%	Explore
microglial cell	11 studies	32% ± 12%	Explore
T cell	10 studies	23% ± 7%	Explore
endothelial cell	9 studies	24% ± 11%	Explore
plasmacytoid dendritic cell	8 studies	23% ± 8%	Explore
non-classical monocyte	7 studies	23% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
dendritic cell	7 studies	32% ± 7%	Explore
GABAergic neuron	7 studies	33% ± 17%	Explore
oligodendrocyte	7 studies	24% ± 8%	Explore
hematopoietic precursor cell	6 studies	32% ± 13%	Explore
myeloid cell	6 studies	28% ± 3%	Explore
astrocyte	6 studies	29% ± 10%	Explore
monocyte	6 studies	29% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	22% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 7%	Explore
lymphocyte	5 studies	29% ± 9%	Explore
mast cell	5 studies	23% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 2%	Explore
deuterosomal cell	4 studies	29% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 1%	Explore
classical monocyte	4 studies	26% ± 8%	Explore
conventional dendritic cell	4 studies	30% ± 19%	Explore
precursor B cell	4 studies	31% ± 8%	Explore
immature B cell	4 studies	24% ± 4%	Explore
pro-B cell	4 studies	30% ± 3%	Explore
mononuclear phagocyte	4 studies	21% ± 4%	Explore
mucosal invariant T cell	4 studies	18% ± 2%	Explore
glutamatergic neuron	4 studies	46% ± 14%	Explore
hematopoietic stem cell	4 studies	23% ± 5%	Explore
leukocyte	4 studies	27% ± 4%	Explore
fibroblast	4 studies	18% ± 1%	Explore
mature NK T cell	3 studies	17% ± 2%	Explore
glial cell	3 studies	20% ± 5%	Explore
progenitor cell	3 studies	20% ± 3%	Explore
plasma cell	3 studies	24% ± 7%	Explore
retinal rod cell	3 studies	19% ± 2%	Explore
germinal center B cell	3 studies	18% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 6%	Explore
ependymal cell	3 studies	43% ± 10%	Explore
granulocyte monocyte progenitor cell	3 studies	32% ± 9%	Explore
alveolar macrophage	3 studies	30% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	18% ± 0%	Explore
T follicular helper cell	3 studies	17% ± 1%	Explore
gamma-delta T cell	3 studies	26% ± 12%	Explore
endothelial cell of lymphatic vessel	3 studies	17% ± 2%	Explore
transit amplifying cell	3 studies	24% ± 10%	Explore
adipocyte	3 studies	20% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 2%	Explore
interneuron	3 studies	48% ± 21%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	7 studies	34% ± 14%	Explore
peripheral blood	5 studies	27% ± 10%	Explore
lung	4 studies	18% ± 3%	Explore
eye	3 studies	18% ± 2%	Explore
bone marrow	3 studies	20% ± 4%	Explore
adipose	3 studies	19% ± 1%	Explore
liver	3 studies	18% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1455.70	1444 / 1445	99%	11.50	182 / 183
breast	100%	1983.24	459 / 459	99%	10.83	1107 / 1118
uterus	100%	2376.82	170 / 170	98%	10.64	451 / 459
thymus	100%	1843.68	653 / 653	98%	10.94	594 / 605
lung	100%	2285.83	577 / 578	98%	9.41	1129 / 1155
bladder	100%	1955.24	21 / 21	97%	7.99	487 / 504
pancreas	98%	908.90	321 / 328	98%	8.46	175 / 178
stomach	100%	1303.66	359 / 359	95%	7.29	273 / 286
intestine	100%	1914.94	966 / 966	95%	7.38	500 / 527
brain	97%	1042.49	2561 / 2642	98%	7.60	689 / 705
prostate	100%	1839.00	245 / 245	94%	5.56	473 / 502
skin	100%	1469.26	1807 / 1809	91%	9.91	431 / 472
adrenal gland	100%	1134.98	257 / 258	89%	4.53	205 / 230
ovary	100%	2542.43	180 / 180	88%	4.85	377 / 430
kidney	97%	1000.36	86 / 89	86%	4.84	775 / 901
liver	91%	517.85	206 / 226	61%	3.13	246 / 406
adipose	100%	1980.75	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1734.78	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	24.37	29 / 29
spleen	100%	4117.83	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	13.59	45 / 45
peripheral blood	97%	2709.74	900 / 929	0%	0	0 / 0
heart	92%	654.62	788 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	56%	2.41	45 / 80
muscle	50%	236.60	401 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1