CDC42SE1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0008360Biological processregulation of cell shape
GO_0035023Biological processregulation of Rho protein signal transduction
GO_0006909Biological processphagocytosis
GO_0030054Cellular componentcell junction
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005095Molecular functionGTPase inhibitor activity
GO_0031267Molecular functionsmall GTPase binding

IV. Literature review

[source]
Gene nameCDC42SE1
Protein nameCDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1)
SynonymsSPEC1
DescriptionFUNCTION: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. .

AccessionsENST00000357235.6 [Q9NRR8-1]
Q9NRR8
ENST00000540998.5 [Q9NRR8-1]
ENST00000439374.6 [Q9NRR8-1]