BRWD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	26 studies	36% ± 16%	Explore
fibroblast	18 studies	28% ± 14%	Explore
astrocyte	18 studies	40% ± 19%	Explore
B cell	15 studies	23% ± 7%	Explore
oligodendrocyte precursor cell	15 studies	42% ± 18%	Explore
oligodendrocyte	15 studies	40% ± 16%	Explore
natural killer cell	14 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	21% ± 5%	Explore
glutamatergic neuron	13 studies	54% ± 25%	Explore
microglial cell	13 studies	47% ± 14%	Explore
pericyte	13 studies	31% ± 15%	Explore
CD8-positive, alpha-beta T cell	13 studies	21% ± 5%	Explore
T cell	12 studies	22% ± 7%	Explore
macrophage	12 studies	36% ± 17%	Explore
ciliated cell	11 studies	26% ± 11%	Explore
GABAergic neuron	11 studies	49% ± 24%	Explore
regulatory T cell	11 studies	20% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	23% ± 4%	Explore
CD4-positive, alpha-beta T cell	10 studies	22% ± 5%	Explore
epithelial cell	10 studies	41% ± 20%	Explore
smooth muscle cell	10 studies	29% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	22% ± 6%	Explore
basal cell	9 studies	36% ± 19%	Explore
adipocyte	9 studies	32% ± 11%	Explore
gamma-delta T cell	9 studies	22% ± 6%	Explore
neuron	8 studies	43% ± 18%	Explore
mucosal invariant T cell	8 studies	21% ± 5%	Explore
type I pneumocyte	8 studies	27% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	24% ± 5%	Explore
mature NK T cell	7 studies	20% ± 7%	Explore
interneuron	7 studies	56% ± 24%	Explore
naive B cell	7 studies	20% ± 5%	Explore
myeloid cell	7 studies	25% ± 6%	Explore
amacrine cell	7 studies	36% ± 13%	Explore
retinal cone cell	7 studies	41% ± 14%	Explore
retinal rod cell	7 studies	40% ± 17%	Explore
dendritic cell	7 studies	32% ± 10%	Explore
memory B cell	6 studies	17% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	24% ± 5%	Explore
club cell	6 studies	34% ± 13%	Explore
retina horizontal cell	6 studies	31% ± 12%	Explore
endothelial cell of lymphatic vessel	6 studies	38% ± 15%	Explore
retinal ganglion cell	5 studies	35% ± 13%	Explore
cardiac muscle cell	5 studies	36% ± 10%	Explore
mast cell	5 studies	24% ± 8%	Explore
Mueller cell	5 studies	32% ± 15%	Explore
abnormal cell	5 studies	29% ± 15%	Explore
monocyte	5 studies	29% ± 7%	Explore
goblet cell	5 studies	33% ± 24%	Explore
type II pneumocyte	5 studies	30% ± 11%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 4%	Explore
secretory cell	4 studies	21% ± 3%	Explore
squamous epithelial cell	4 studies	37% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	26% ± 5%	Explore
non-classical monocyte	4 studies	22% ± 5%	Explore
granule cell	4 studies	41% ± 9%	Explore
progenitor cell	4 studies	33% ± 10%	Explore
retinal bipolar neuron	4 studies	26% ± 5%	Explore
retinal pigment epithelial cell	4 studies	39% ± 22%	Explore
mesothelial cell	4 studies	32% ± 10%	Explore
lymphocyte	4 studies	38% ± 16%	Explore
respiratory goblet cell	4 studies	37% ± 14%	Explore
T follicular helper cell	4 studies	18% ± 3%	Explore
leukocyte	4 studies	42% ± 16%	Explore
myofibroblast cell	4 studies	31% ± 16%	Explore
hematopoietic precursor cell	3 studies	29% ± 10%	Explore
ionocyte	3 studies	42% ± 7%	Explore
classical monocyte	3 studies	22% ± 4%	Explore
plasmablast	3 studies	34% ± 8%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	44% ± 6%	Explore
GABAergic interneuron	3 studies	49% ± 2%	Explore
glial cell	3 studies	31% ± 7%	Explore
precursor B cell	3 studies	23% ± 2%	Explore
plasma cell	3 studies	32% ± 3%	Explore
endothelial cell of artery	3 studies	20% ± 4%	Explore
mononuclear phagocyte	3 studies	24% ± 6%	Explore
vein endothelial cell	3 studies	40% ± 20%	Explore
GABAergic amacrine cell	3 studies	42% ± 12%	Explore
OFF-bipolar cell	3 studies	32% ± 13%	Explore
ON-bipolar cell	3 studies	35% ± 12%	Explore
glycinergic amacrine cell	3 studies	37% ± 7%	Explore
rod bipolar cell	3 studies	30% ± 15%	Explore
germinal center B cell	3 studies	26% ± 9%	Explore
endothelial cell of vascular tree	3 studies	35% ± 22%	Explore
hepatocyte	3 studies	57% ± 16%	Explore
neural progenitor cell	3 studies	41% ± 10%	Explore
connective tissue cell	3 studies	24% ± 4%	Explore
ependymal cell	3 studies	47% ± 14%	Explore
enteroendocrine cell	3 studies	24% ± 8%	Explore
alveolar macrophage	3 studies	35% ± 12%	Explore
capillary endothelial cell	3 studies	26% ± 8%	Explore
chondrocyte	3 studies	33% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	22% ± 3%	Explore
muscle cell	3 studies	37% ± 28%	Explore
transit amplifying cell	3 studies	41% ± 34%	Explore
brush cell	3 studies	20% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 6%	Explore
mural cell	3 studies	42% ± 12%	Explore
mucus secreting cell	3 studies	35% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	46% ± 21%	Explore
lung	9 studies	25% ± 9%	Explore
peripheral blood	7 studies	24% ± 5%	Explore
eye	7 studies	43% ± 17%	Explore
heart	4 studies	30% ± 7%	Explore
liver	4 studies	33% ± 15%	Explore
adipose	4 studies	28% ± 8%	Explore
intestine	3 studies	21% ± 4%	Explore
kidney	3 studies	29% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5439.41	1445 / 1445	100%	11.71	183 / 183
prostate	100%	4703.10	245 / 245	100%	9.85	502 / 502
breast	100%	5537.75	459 / 459	100%	19.03	1117 / 1118
brain	100%	5953.39	2638 / 2642	100%	14.11	705 / 705
lung	100%	5171.21	578 / 578	100%	9.14	1152 / 1155
thymus	100%	5863.95	653 / 653	100%	11.36	603 / 605
uterus	100%	5143.45	170 / 170	100%	10.05	457 / 459
pancreas	100%	3423.90	328 / 328	99%	9.07	176 / 178
ovary	100%	5810.34	180 / 180	99%	6.09	425 / 430
bladder	100%	4908.33	21 / 21	99%	9.51	498 / 504
adrenal gland	100%	4406.30	258 / 258	99%	8.83	227 / 230
kidney	100%	3117.52	89 / 89	97%	8.37	873 / 901
intestine	100%	4805.40	966 / 966	97%	7.39	510 / 527
stomach	100%	3764.58	359 / 359	97%	8.08	276 / 286
liver	100%	2625.77	226 / 226	94%	5.22	381 / 406
skin	100%	5301.44	1809 / 1809	92%	7.25	433 / 472
blood vessel	100%	4632.89	1335 / 1335	0%	0	0 / 0
muscle	100%	4184.89	803 / 803	0%	0	0 / 0
spleen	100%	4001.43	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	9.95	45 / 45
ureter	0%	0	0 / 0	100%	3.25	1 / 1
adipose	100%	4607.97	1203 / 1204	0%	0	0 / 0
heart	97%	3025.78	839 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	7.38	28 / 29
eye	0%	0	0 / 0	80%	5.05	64 / 80
peripheral blood	65%	1485.82	607 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008360	Biological process	regulation of cell shape
GO_0007010	Biological process	cytoskeleton organization
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0060170	Cellular component	ciliary membrane
GO_0005930	Cellular component	axoneme
GO_0005730	Cellular component	nucleolus
GO_0031514	Cellular component	motile cilium
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	BRWD1
Protein name	Bromodomain and WD repeat domain containing 1 Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) Alternative protein BRWD1
Synonyms	WDR9 C21orf107 hCG_1812840
Description	FUNCTION: May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. .
Accessions	ENST00000424441.1 ENST00000445245.5 ENST00000455867.5 A5PLN2 Q9NSI6 H0Y500 H0Y4A7 ENST00000342449.8 [Q9NSI6-2] H7BZR9 ENST00000446924.5 H0Y5I9 H0Y463 ENST00000380800.7 [Q9NSI6-3] H0Y4R9 ENST00000333229.6 [Q9NSI6-1] H7C409 ENST00000341322.4 [Q9NSI6-4] ENST00000430093.5 ENST00000412604.1 ENST00000445668.5 L8E8H4

BRWD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review