ATF6B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034976Biological processresponse to endoplasmic reticulum stress
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0007165Biological processsignal transduction
GO_0036500Biological processATF6-mediated unfolded protein response
GO_0030968Biological processendoplasmic reticulum unfolded protein response
GO_1903892Biological processnegative regulation of ATF6-mediated unfolded protein response
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0032993Cellular componentprotein-DNA complex
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005654Cellular componentnucleoplasm
GO_0005794Cellular componentGolgi apparatus
GO_0000139Cellular componentGolgi membrane
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATF6B
Protein nameCyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta) (Activating transcription factor 6 beta) (ATF6-beta) (Protein G13) (cAMP response element-binding protein-related protein) (Creb-rp) (cAMP-responsive element-binding protein-like 1) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 beta]
Cyclic AMP-dependent transcription factor ATF-6 beta
ATF6B protein (cAMP responsive element binding protein-like 1)
Activating transcription factor 6 beta
SynonymsCREBL1
G13
DescriptionFUNCTION: [Cyclic AMP-dependent transcription factor ATF-6 beta]: Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 beta), which is embedded in the endoplasmic reticulum membrane . Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR) . .; FUNCTION: [Processed cyclic AMP-dependent transcription factor ATF-6 beta]: Transcription factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress . Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE . .

AccessionsENST00000293709.10 [Q99941-1]
ENST00000375201.8 [Q99941-2]
Q99941
ENST00000439240.6 [Q99941-2]
ENST00000413319.1
Q96QL7
ENST00000435768.6 [Q99941-2]
A0A0G2JIM1
ENST00000425571.6 [Q99941-1]
H0Y7D7
Q6AZW6
ENST00000436157.1
ENST00000383156.8 [Q99941-2]
ENST00000375203.8 [Q99941-1]
ENST00000453203.2
ENST00000417614.1
ENST00000427136.6 [Q99941-1]