ACAP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	38 studies	42% ± 15%	Explore
T cell	36 studies	40% ± 16%	Explore
CD8-positive, alpha-beta T cell	36 studies	46% ± 13%	Explore
B cell	34 studies	37% ± 12%	Explore
CD4-positive, alpha-beta T cell	33 studies	47% ± 12%	Explore
regulatory T cell	28 studies	44% ± 12%	Explore
mature NK T cell	21 studies	43% ± 14%	Explore
memory B cell	20 studies	39% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	41% ± 14%	Explore
gamma-delta T cell	18 studies	47% ± 16%	Explore
naive B cell	18 studies	33% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	49% ± 14%	Explore
mucosal invariant T cell	16 studies	39% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	43% ± 13%	Explore
plasmacytoid dendritic cell	14 studies	31% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	51% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	44% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	49% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	49% ± 11%	Explore
T follicular helper cell	9 studies	49% ± 10%	Explore
innate lymphoid cell	8 studies	41% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	38% ± 13%	Explore
CD4-positive helper T cell	6 studies	35% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	46% ± 16%	Explore
leukocyte	6 studies	27% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 14%	Explore
hematopoietic precursor cell	5 studies	36% ± 16%	Explore
plasma cell	5 studies	31% ± 12%	Explore
exhausted T cell	5 studies	59% ± 13%	Explore
classical monocyte	5 studies	29% ± 12%	Explore
hematopoietic stem cell	5 studies	25% ± 3%	Explore
lymphocyte	5 studies	36% ± 13%	Explore
ciliated cell	5 studies	25% ± 9%	Explore
T-helper 17 cell	5 studies	53% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	40% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	35% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	38% ± 12%	Explore
conventional dendritic cell	4 studies	40% ± 22%	Explore
precursor B cell	4 studies	22% ± 4%	Explore
immature B cell	4 studies	34% ± 3%	Explore
dendritic cell	4 studies	36% ± 15%	Explore
group 3 innate lymphoid cell	4 studies	52% ± 14%	Explore
T-helper 1 cell	4 studies	52% ± 9%	Explore
double negative thymocyte	4 studies	51% ± 10%	Explore
plasmablast	3 studies	43% ± 14%	Explore
thymocyte	3 studies	28% ± 17%	Explore
myeloid cell	3 studies	23% ± 5%	Explore
intraepithelial lymphocyte	3 studies	51% ± 9%	Explore
germinal center B cell	3 studies	30% ± 5%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	50% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	35% ± 11%	Explore
lung	6 studies	23% ± 4%	Explore
lymph node	3 studies	41% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	98%	988.68	641 / 653	98%	18.36	590 / 605
prostate	98%	775.31	239 / 245	98%	5.40	492 / 502
lung	100%	2370.26	578 / 578	93%	7.67	1076 / 1155
uterus	91%	429.25	155 / 170	87%	6.07	401 / 459
breast	88%	423.72	403 / 459	76%	5.27	852 / 1118
kidney	76%	694.31	68 / 89	87%	5.82	788 / 901
stomach	86%	538.54	307 / 359	72%	4.31	205 / 286
intestine	77%	1833.89	741 / 966	74%	4.25	390 / 527
bladder	76%	688.52	16 / 21	74%	4.79	375 / 504
esophagus	68%	343.53	983 / 1445	81%	4.06	149 / 183
skin	61%	264.82	1099 / 1809	68%	7.55	323 / 472
liver	81%	394.19	182 / 226	44%	2.62	178 / 406
ovary	46%	181.74	83 / 180	77%	3.07	331 / 430
adrenal gland	45%	159.88	116 / 258	73%	3.32	168 / 230
brain	40%	161.27	1061 / 2642	73%	2.50	512 / 705
pancreas	13%	48.89	43 / 328	89%	7.85	158 / 178
lymph node	0%	0	0 / 0	100%	83.61	29 / 29
peripheral blood	100%	17345.56	929 / 929	0%	0	0 / 0
spleen	100%	13056.89	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.44	1 / 1
tonsil	0%	0	0 / 0	98%	12.21	44 / 45
adipose	96%	678.10	1155 / 1204	0%	0	0 / 0
blood vessel	52%	313.56	700 / 1335	0%	0	0 / 0
heart	46%	186.50	395 / 861	0%	0	0 / 0
muscle	30%	88.73	237 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	20%	1.05	16 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0015031	Biological process	protein transport
GO_0055038	Cellular component	recycling endosome membrane
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	ACAP1
Protein name	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1) Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein (Cnt-b) (Centaurin-beta)
Synonyms	CENTB1 KIAA0050
Description	FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. . FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. . FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. .
Accessions	I3L0K9 I3L268 ENST00000575425.1 Q15027 ENST00000570457.6 ENST00000672212.1 ENST00000158762.8

ACAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review