ABHD14B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050427Biological process3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0016787Molecular functionhydrolase activity
GO_0005515Molecular functionprotein binding
GO_0061733Molecular functionpeptide-lysine-N-acetyltransferase activity

IV. Literature review

[source]
Gene nameABHD14B
Protein namePutative protein-lysine deacylase ABHD14B (EC 2.3.1.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) (CCG1-interacting factor B)
Putative protein-lysine deacylase ABHD14B (Alpha/beta hydrolase domain-containing protein 14B)
SynonymsCIB
hCG_42593
HEL-S-299
DescriptionFUNCTION: Acts as an atypical protein-lysine deacetylase in vitro . Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues . Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate . May activate transcription . .

AccessionsENST00000395008.6 [Q96IU4-1]
V9HW87
ENST00000483233.5 [Q96IU4-1]
ENST00000315877.14
ENST00000461108.5
Q96IU4
ENST00000525795.1 [Q96IU4-1]
ENST00000361143.10 [Q96IU4-1]
B4DQI4
F8W9U3