GO_0046512 | sphingosine biosynthetic process | OmnibusX

sphingosine biosynthetic process

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	SPHK2 SPTLC2 ACER2 ABCA2 SPTLC1 ASAH1	dopaminergic neuron glutamatergic neuron	5 studies
Group 2	SPTSSB	CD16-negative, CD56-bright natural killer cell, human glutamatergic neuron	10 studies
Group 3	SPHK1 SPTSSA	epithelial cell endothelial cell	8 studies
Group 4	SPTLC3 ACER3	epithelial cell basal cell macrophage microglial cell	10 studies
Group 5	GBA1	myeloid cell	10 studies

II. Literature review

Name	sphingosine biosynthetic process
ID	GO_0046512
collection_id	Biological process
Exact synonym	sphingosine anabolism, sphingosine biosynthesis, sphingosine formation, sphingosine synthesis
Description	The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
External URL
Genes	ASAH1 GBA1 ASAH2 SPHK1 ABCA2 spt-c2-sa_human spt-c3-sb_human SPTLC3 SPHK2 SPTLC2 SPTLC1 SPTSSA ACER1 spt-c3-sa_human spt-c2-sb_human SPTSSB ACER2 ACER3