Biological process

keratan sulfate anabolism, keratan sulfate biosynthesis, keratan sulfate formation, keratan sulfate synthesis, keratan sulphate biosynthesis, keratan sulphate biosynthetic process

The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.