B3GNT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of B3GNT2 at tissue level.

III. Associated gene sets

GO_0016266Biological processO-glycan processing
GO_1990830Biological processcellular response to leukemia inhibitory factor
GO_0007608Biological processsensory perception of smell
GO_0030311Biological processpoly-N-acetyllactosamine biosynthetic process
GO_0006493Biological processprotein O-linked glycosylation
GO_0018146Biological processkeratan sulfate biosynthetic process
GO_0007411Biological processaxon guidance
GO_0000139Cellular componentGolgi membrane
GO_0008499Molecular functionUDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0008532Molecular functionN-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

IV. Literature review

[source]
Gene nameB3GNT2
Protein nameN-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (EC 2.4.1.149) (Beta-1,3-N-acetylglucosaminyltransferase 1) (BGnT-1) (Beta-1,3-Gn-T1) (Beta3Gn-T1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (Beta3GalT7) (b3Gal-T7) (Beta-3-Gx-T7) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) (BGnT-2) (Beta-1,3-Gn-T2) (Beta-1,3-N-acetylglucosaminyltransferase 2) (Beta3Gn-T2) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7)
SynonymsB3GNT1
B3GALT7
DescriptionFUNCTION: Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors . Probably constitutes the main polylactosamine synthase. .

AccessionsQ9NY97
ENST00000301998.5 [Q9NY97-1]
ENST00000405767.1 [Q9NY97-1]