I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 9 studies | 30% ± 11% | |
| epithelial cell | 4 studies | 31% ± 7% | |
| goblet cell | 3 studies | 20% ± 3% | |
| hepatocyte | 3 studies | 38% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 9 studies | 30% ± 11% | |
| epithelial cell | 4 studies | 31% ± 7% | |
| goblet cell | 3 studies | 20% ± 3% | |
| hepatocyte | 3 studies | 38% ± 11% |
Insufficient scRNA-seq data for expression of SLC35D2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1146.46 | 1445 / 1445 | 100% | 5.66 | 183 / 183 |
| liver | 100% | 1987.53 | 226 / 226 | 100% | 7.15 | 406 / 406 |
| pancreas | 100% | 1460.93 | 328 / 328 | 100% | 6.22 | 178 / 178 |
| prostate | 100% | 1184.47 | 245 / 245 | 100% | 4.72 | 502 / 502 |
| intestine | 100% | 2053.23 | 966 / 966 | 100% | 9.95 | 526 / 527 |
| ovary | 100% | 1337.63 | 180 / 180 | 100% | 5.11 | 429 / 430 |
| thymus | 100% | 2046.14 | 653 / 653 | 100% | 4.15 | 603 / 605 |
| stomach | 100% | 1567.08 | 359 / 359 | 100% | 9.88 | 285 / 286 |
| breast | 100% | 1231.41 | 459 / 459 | 99% | 3.25 | 1110 / 1118 |
| skin | 100% | 901.58 | 1809 / 1809 | 99% | 4.88 | 467 / 472 |
| bladder | 100% | 1239.10 | 21 / 21 | 99% | 5.82 | 498 / 504 |
| uterus | 100% | 1188.15 | 170 / 170 | 99% | 3.29 | 453 / 459 |
| lung | 100% | 1388.58 | 577 / 578 | 98% | 4.09 | 1137 / 1155 |
| kidney | 100% | 2018.18 | 89 / 89 | 98% | 4.37 | 884 / 901 |
| adrenal gland | 99% | 736.41 | 256 / 258 | 92% | 3.81 | 212 / 230 |
| brain | 83% | 510.23 | 2189 / 2642 | 98% | 3.61 | 690 / 705 |
| adipose | 100% | 1155.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 7.96 | 80 / 80 |
| spleen | 100% | 865.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.56 | 1 / 1 |
| blood vessel | 100% | 977.01 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 657.28 | 846 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 2.32 | 44 / 45 |
| peripheral blood | 96% | 594.30 | 893 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 2.07 | 25 / 29 |
| muscle | 44% | 130.24 | 355 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015789 | Biological process | UDP-N-acetylgalactosamine transmembrane transport |
| GO_0015012 | Biological process | heparan sulfate proteoglycan biosynthetic process |
| GO_0015780 | Biological process | nucleotide-sugar transmembrane transport |
| GO_0018146 | Biological process | keratan sulfate biosynthetic process |
| GO_0008150 | Biological process | biological_process |
| GO_1990569 | Biological process | UDP-N-acetylglucosamine transmembrane transport |
| GO_0015787 | Biological process | UDP-glucuronic acid transmembrane transport |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005338 | Molecular function | nucleotide-sugar transmembrane transporter activity |
| GO_0005462 | Molecular function | UDP-N-acetylglucosamine transmembrane transporter activity |
| GO_0015297 | Molecular function | antiporter activity |
| GO_0005461 | Molecular function | UDP-glucuronic acid transmembrane transporter activity |
| GO_0005463 | Molecular function | UDP-N-acetylgalactosamine transmembrane transporter activity |
| Gene name | SLC35D2 |
| Protein name | Nucleotide sugar transporter SLC35D2 Nucleotide sugar transporter SLC35D2 (Homolog of Fringe connection protein 1) (HFRC1) (SQV7-like protein) (SQV7L) (Solute carrier family 35 member D2) (UDP-galactose transporter-related protein 8) (UGTrel8) Solute carrier family 35 member D2 |
| Synonyms | UGTREL8 HFRC |
| Description | FUNCTION: Nucleotide sugar antiporter transporting UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-glucose (UDP-Glc) from the cytosol into the lumen of the Golgi in exchange of UMP. By supplying UDP-N-acetylglucosamine, a donor substrate to heparan sulfate synthases, probably takes part in the synthesis of these glycoconjugates. . |
| Accessions | A0A3B3IU97 ENST00000650065.1 Q5VZJ2 Q76EJ3 ENST00000643789.1 A0A3B3ITR5 ENST00000490599.2 ENST00000375257.2 ENST00000253270.13 [Q76EJ3-1] ENST00000375259.9 [Q76EJ3-2] A0A2R8Y5X9 |
