Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 12 studies | 39% ± 18% | |
| endothelial cell | 12 studies | 31% ± 12% | |
| microglial cell | 12 studies | 36% ± 14% | |
| adipocyte | 8 studies | 31% ± 8% | |
| macrophage | 8 studies | 30% ± 10% | |
| glutamatergic neuron | 8 studies | 40% ± 25% | |
| astrocyte | 7 studies | 26% ± 7% | |
| dendritic cell | 7 studies | 22% ± 4% | |
| ciliated cell | 6 studies | 26% ± 14% | |
| myeloid cell | 6 studies | 27% ± 15% | |
| type II pneumocyte | 6 studies | 24% ± 7% | |
| oligodendrocyte | 6 studies | 28% ± 11% | |
| GABAergic neuron | 5 studies | 40% ± 17% | |
| podocyte | 5 studies | 68% ± 19% | |
| cardiac muscle cell | 5 studies | 41% ± 13% | |
| endothelial cell of lymphatic vessel | 5 studies | 26% ± 6% | |
| interneuron | 4 studies | 36% ± 19% | |
| conventional dendritic cell | 3 studies | 21% ± 3% | |
| glial cell | 3 studies | 27% ± 5% | |
| neuron | 3 studies | 25% ± 7% | |
| hepatocyte | 3 studies | 73% ± 20% | |
| alveolar macrophage | 3 studies | 32% ± 10% | |
| monocyte | 3 studies | 27% ± 8% | |
| mast cell | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 960.98 | 2631 / 2642 | 100% | 14.47 | 703 / 705 |
| adrenal gland | 100% | 1140.81 | 258 / 258 | 90% | 13.86 | 207 / 230 |
| liver | 100% | 3017.09 | 226 / 226 | 89% | 9.74 | 362 / 406 |
| kidney | 100% | 1478.33 | 89 / 89 | 85% | 7.54 | 768 / 901 |
| breast | 100% | 846.91 | 457 / 459 | 79% | 4.26 | 884 / 1118 |
| skin | 78% | 1160.92 | 1407 / 1809 | 100% | 61.71 | 471 / 472 |
| pancreas | 93% | 391.91 | 306 / 328 | 82% | 4.40 | 146 / 178 |
| thymus | 99% | 611.21 | 648 / 653 | 75% | 5.53 | 455 / 605 |
| prostate | 96% | 509.01 | 235 / 245 | 76% | 3.20 | 381 / 502 |
| lung | 98% | 771.87 | 565 / 578 | 73% | 3.81 | 842 / 1155 |
| ovary | 74% | 240.22 | 134 / 180 | 90% | 7.53 | 388 / 430 |
| uterus | 89% | 348.18 | 151 / 170 | 62% | 2.98 | 284 / 459 |
| esophagus | 94% | 412.85 | 1361 / 1445 | 45% | 1.99 | 82 / 183 |
| stomach | 100% | 684.98 | 358 / 359 | 29% | 1.15 | 84 / 286 |
| intestine | 90% | 534.55 | 868 / 966 | 19% | 0.72 | 101 / 527 |
| eye | 0% | 0 | 0 / 0 | 100% | 44.74 | 80 / 80 |
| bladder | 71% | 270.19 | 15 / 21 | 28% | 1.31 | 142 / 504 |
| adipose | 100% | 907.02 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| heart | 100% | 1895.95 | 857 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 97% | 639.59 | 1298 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 92% | 388.52 | 222 / 241 | 0% | 0 | 0 / 0 |
| muscle | 89% | 459.81 | 716 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 2.69 | 34 / 45 |
| peripheral blood | 62% | 448.32 | 572 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 0.99 | 6 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071354 | Biological process | cellular response to interleukin-6 |
| GO_0009312 | Biological process | oligosaccharide biosynthetic process |
| GO_0009247 | Biological process | glycolipid biosynthetic process |
| GO_0018146 | Biological process | keratan sulfate biosynthetic process |
| GO_0006486 | Biological process | protein glycosylation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0016020 | Cellular component | membrane |
| GO_0008373 | Molecular function | sialyltransferase activity |
| GO_0003836 | Molecular function | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity |
| Gene name | ST3GAL6 |
| Protein name | Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (ST3GalVI) (Sialyltransferase 10) Type 2 lactosamine alpha-2,3-sialyltransferase (CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (Sialyltransferase 10) ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| Synonyms | SIAT10 hCG_18894 |
| Description | FUNCTION: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. FUNCTION: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. . |
| Accessions | A0A087WXB8 ENST00000394162.5 [Q9Y274-1] C9JWJ3 ENST00000460774.5 F2Z2F4 C9IZL6 ENST00000468553.5 ENST00000486334.6 ENST00000492254.6 ENST00000485145.1 ENST00000613264 ENST00000483910.6 [Q9Y274-1] ENST00000613264.5 [Q9Y274-1] ENST00000497008.5 ENST00000265261.11 [Q9Y274-1] ENST00000476833.5 Q9Y274 ENST00000486249.5 C9J480 C9J0E2 C9JMW7 C9JWI9 C9J9Y4 ENST00000495376.5 ENST00000469105.5 ENST00000485391.5 |