UQCC2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	15 studies	25% ± 10%	Explore
epithelial cell	13 studies	32% ± 18%	Explore
basal cell	12 studies	34% ± 19%	Explore
fibroblast	11 studies	28% ± 11%	Explore
smooth muscle cell	11 studies	21% ± 4%	Explore
endothelial cell	10 studies	28% ± 11%	Explore
ciliated cell	9 studies	37% ± 18%	Explore
conventional dendritic cell	9 studies	25% ± 10%	Explore
connective tissue cell	8 studies	27% ± 9%	Explore
endothelial cell of lymphatic vessel	8 studies	28% ± 9%	Explore
CD8-positive, alpha-beta T cell	8 studies	27% ± 7%	Explore
plasma cell	7 studies	30% ± 14%	Explore
T cell	7 studies	21% ± 5%	Explore
CD4-positive, alpha-beta T cell	7 studies	31% ± 9%	Explore
pericyte	7 studies	19% ± 6%	Explore
club cell	6 studies	33% ± 7%	Explore
respiratory goblet cell	6 studies	27% ± 12%	Explore
secretory cell	6 studies	32% ± 22%	Explore
non-classical monocyte	6 studies	23% ± 5%	Explore
progenitor cell	6 studies	26% ± 13%	Explore
retinal cone cell	6 studies	55% ± 30%	Explore
natural killer cell	6 studies	25% ± 8%	Explore
hematopoietic precursor cell	5 studies	26% ± 10%	Explore
plasmablast	5 studies	43% ± 22%	Explore
myofibroblast cell	5 studies	23% ± 4%	Explore
transit amplifying cell	5 studies	21% ± 1%	Explore
retinal rod cell	5 studies	34% ± 16%	Explore
myeloid cell	5 studies	24% ± 11%	Explore
regulatory T cell	5 studies	23% ± 6%	Explore
classical monocyte	4 studies	22% ± 6%	Explore
kidney loop of Henle epithelial cell	4 studies	28% ± 5%	Explore
epithelial cell of proximal tubule	4 studies	22% ± 3%	Explore
mesothelial cell	4 studies	29% ± 13%	Explore
B cell	4 studies	21% ± 7%	Explore
retinal ganglion cell	4 studies	44% ± 27%	Explore
erythroblast	4 studies	41% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	17% ± 1%	Explore
retina horizontal cell	4 studies	32% ± 14%	Explore
monocyte	4 studies	23% ± 7%	Explore
erythrocyte	4 studies	37% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	20% ± 3%	Explore
neuron	4 studies	31% ± 13%	Explore
mast cell	4 studies	20% ± 5%	Explore
abnormal cell	4 studies	31% ± 9%	Explore
goblet cell	4 studies	25% ± 9%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 7%	Explore
deuterosomal cell	3 studies	40% ± 8%	Explore
ionocyte	3 studies	28% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	26% ± 2%	Explore
renal alpha-intercalated cell	3 studies	38% ± 6%	Explore
neural crest cell	3 studies	30% ± 2%	Explore
retinal bipolar neuron	3 studies	50% ± 19%	Explore
common myeloid progenitor	3 studies	27% ± 6%	Explore
neuroendocrine cell	3 studies	35% ± 11%	Explore
amacrine cell	3 studies	38% ± 13%	Explore
astrocyte	3 studies	29% ± 5%	Explore
alveolar macrophage	3 studies	20% ± 1%	Explore
serous secreting cell	3 studies	32% ± 3%	Explore
OFF-bipolar cell	3 studies	28% ± 9%	Explore
ON-bipolar cell	3 studies	27% ± 10%	Explore
rod bipolar cell	3 studies	39% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
intermediate monocyte	3 studies	24% ± 4%	Explore
glutamatergic neuron	3 studies	35% ± 9%	Explore
dendritic cell	3 studies	37% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	31% ± 8%	Explore
hematopoietic stem cell	3 studies	19% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	37% ± 19%	Explore
enteroendocrine cell	3 studies	33% ± 14%	Explore
interneuron	3 studies	30% ± 14%	Explore
oligodendrocyte	3 studies	24% ± 6%	Explore
plasmacytoid dendritic cell	3 studies	24% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	29% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	22% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	34% ± 18%	Explore
intestine	6 studies	22% ± 10%	Explore
eye	6 studies	32% ± 16%	Explore
brain	6 studies	24% ± 5%	Explore
kidney	4 studies	20% ± 3%	Explore
liver	4 studies	32% ± 24%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1378.46	258 / 258	100%	29.02	230 / 230
liver	100%	857.34	226 / 226	100%	24.83	406 / 406
ovary	100%	732.68	180 / 180	100%	29.16	430 / 430
pancreas	100%	725.66	328 / 328	100%	18.06	178 / 178
uterus	100%	1197.46	170 / 170	100%	35.94	459 / 459
brain	100%	1477.40	2639 / 2642	100%	32.67	705 / 705
esophagus	100%	849.04	1441 / 1445	100%	14.78	183 / 183
stomach	100%	820.10	358 / 359	100%	18.77	286 / 286
thymus	100%	1097.53	651 / 653	100%	22.03	605 / 605
prostate	100%	1317.19	245 / 245	100%	29.48	500 / 502
breast	100%	763.68	458 / 459	100%	28.16	1113 / 1118
skin	99%	1070.98	1795 / 1809	100%	29.09	472 / 472
bladder	100%	1025.33	21 / 21	99%	28.68	500 / 504
intestine	100%	899.24	965 / 966	99%	23.30	523 / 527
lung	97%	737.68	559 / 578	100%	26.82	1154 / 1155
kidney	100%	1159.70	89 / 89	96%	12.72	868 / 901
eye	0%	0	0 / 0	100%	33.72	80 / 80
lymph node	0%	0	0 / 0	100%	28.22	29 / 29
muscle	100%	1967.18	803 / 803	0%	0	0 / 0
spleen	100%	925.53	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	25.99	45 / 45
ureter	0%	0	0 / 0	100%	48.39	1 / 1
heart	100%	2847.01	858 / 861	0%	0	0 / 0
adipose	97%	642.88	1172 / 1204	0%	0	0 / 0
blood vessel	97%	592.74	1295 / 1335	0%	0	0 / 0
peripheral blood	52%	444.33	487 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0070131	Biological process	positive regulation of mitochondrial translation
GO_0034551	Biological process	mitochondrial respiratory chain complex III assembly
GO_0050796	Biological process	regulation of insulin secretion
GO_2001014	Biological process	regulation of skeletal muscle cell differentiation
GO_0002082	Biological process	regulation of oxidative phosphorylation
GO_0005758	Cellular component	mitochondrial intermembrane space
GO_0016604	Cellular component	nuclear body
GO_0005759	Cellular component	mitochondrial matrix
GO_0042645	Cellular component	mitochondrial nucleoid
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	UQCC2
Protein name	Mitochondrial nucleoid factor 1 (Mitochondrial protein M19) Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19)
Synonyms	MNF1 C6orf125
Description	FUNCTION: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. .
Accessions	Q5TAQ0 Q9BRT2 V5IRT4 ENST00000607484.6 ENST00000374231.8 ENST00000374214.3

UQCC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review