TMEM87A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	27 studies	23% ± 8%	Explore
endothelial cell	24 studies	27% ± 9%	Explore
pericyte	15 studies	24% ± 5%	Explore
smooth muscle cell	14 studies	20% ± 3%	Explore
oligodendrocyte	13 studies	37% ± 14%	Explore
type I pneumocyte	12 studies	38% ± 12%	Explore
type II pneumocyte	12 studies	48% ± 19%	Explore
basal cell	12 studies	27% ± 11%	Explore
ciliated cell	12 studies	29% ± 11%	Explore
astrocyte	12 studies	27% ± 11%	Explore
natural killer cell	11 studies	20% ± 4%	Explore
regulatory T cell	11 studies	17% ± 1%	Explore
epithelial cell	11 studies	35% ± 20%	Explore
endothelial cell of lymphatic vessel	9 studies	24% ± 8%	Explore
myofibroblast cell	9 studies	22% ± 6%	Explore
adipocyte	9 studies	30% ± 6%	Explore
oligodendrocyte precursor cell	9 studies	30% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	20% ± 3%	Explore
CD8-positive, alpha-beta T cell	8 studies	18% ± 4%	Explore
macrophage	8 studies	24% ± 6%	Explore
T cell	7 studies	22% ± 11%	Explore
B cell	7 studies	21% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	17% ± 2%	Explore
microglial cell	7 studies	24% ± 7%	Explore
club cell	7 studies	35% ± 11%	Explore
respiratory goblet cell	6 studies	29% ± 11%	Explore
GABAergic neuron	6 studies	34% ± 16%	Explore
CD4-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	19% ± 5%	Explore
mature NK T cell	6 studies	18% ± 3%	Explore
capillary endothelial cell	6 studies	18% ± 2%	Explore
connective tissue cell	6 studies	20% ± 4%	Explore
dendritic cell	6 studies	26% ± 14%	Explore
abnormal cell	6 studies	26% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 4%	Explore
goblet cell	6 studies	34% ± 23%	Explore
secretory cell	5 studies	22% ± 4%	Explore
neuron	5 studies	30% ± 14%	Explore
glutamatergic neuron	5 studies	44% ± 18%	Explore
naive B cell	5 studies	18% ± 1%	Explore
myeloid cell	5 studies	21% ± 5%	Explore
retinal rod cell	5 studies	20% ± 3%	Explore
mucus secreting cell	5 studies	26% ± 8%	Explore
endothelial cell of artery	5 studies	17% ± 1%	Explore
lymphocyte	5 studies	25% ± 8%	Explore
endothelial cell of vascular tree	5 studies	22% ± 5%	Explore
gamma-delta T cell	5 studies	21% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
classical monocyte	4 studies	23% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	16% ± 1%	Explore
mucosal invariant T cell	4 studies	17% ± 1%	Explore
retinal pigment epithelial cell	4 studies	28% ± 10%	Explore
Mueller cell	4 studies	20% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	28% ± 5%	Explore
mast cell	4 studies	24% ± 6%	Explore
brush cell	4 studies	32% ± 12%	Explore
interneuron	4 studies	36% ± 21%	Explore
ionocyte	3 studies	28% ± 4%	Explore
leukocyte	3 studies	16% ± 1%	Explore
hematopoietic precursor cell	3 studies	21% ± 4%	Explore
non-classical monocyte	3 studies	30% ± 9%	Explore
plasmablast	3 studies	32% ± 12%	Explore
glomerular endothelial cell	3 studies	20% ± 3%	Explore
glial cell	3 studies	23% ± 4%	Explore
squamous epithelial cell	3 studies	34% ± 24%	Explore
retinal cone cell	3 studies	23% ± 1%	Explore
mesothelial cell	3 studies	21% ± 4%	Explore
mononuclear phagocyte	3 studies	19% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 7%	Explore
hepatocyte	3 studies	55% ± 23%	Explore
adventitial cell	3 studies	22% ± 8%	Explore
alveolar macrophage	3 studies	25% ± 9%	Explore
monocyte	3 studies	30% ± 4%	Explore
T follicular helper cell	3 studies	18% ± 1%	Explore
Schwann cell	3 studies	26% ± 7%	Explore
transit amplifying cell	3 studies	32% ± 21%	Explore
plasmacytoid dendritic cell	3 studies	23% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	16% ± 0%	Explore
myoepithelial cell	3 studies	22% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	18% ± 4%	Explore
luminal cell of prostate epithelium	3 studies	30% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	30% ± 16%	Explore
lung	13 studies	26% ± 8%	Explore
eye	7 studies	22% ± 8%	Explore
peripheral blood	4 studies	24% ± 6%	Explore
breast	4 studies	19% ± 2%	Explore
intestine	4 studies	20% ± 5%	Explore
adipose	4 studies	22% ± 5%	Explore
heart	3 studies	16% ± 1%	Explore
prostate	3 studies	21% ± 6%	Explore
liver	3 studies	29% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3367.20	1445 / 1445	100%	33.46	183 / 183
lung	100%	4695.54	578 / 578	100%	46.07	1155 / 1155
prostate	100%	4202.15	245 / 245	100%	108.36	502 / 502
breast	100%	4547.24	459 / 459	100%	69.76	1115 / 1118
brain	99%	1942.90	2626 / 2642	100%	40.78	705 / 705
bladder	100%	3427.62	21 / 21	99%	41.25	500 / 504
intestine	100%	3200.83	966 / 966	99%	38.42	522 / 527
thymus	100%	4137.74	653 / 653	99%	68.53	599 / 605
uterus	100%	3227.12	170 / 170	99%	36.69	454 / 459
pancreas	100%	1995.42	328 / 328	99%	39.05	176 / 178
stomach	100%	2565.90	359 / 359	98%	31.58	280 / 286
kidney	100%	1835.87	89 / 89	97%	31.72	877 / 901
ovary	100%	2968.79	180 / 180	97%	22.63	416 / 430
skin	100%	4396.92	1809 / 1809	96%	41.88	455 / 472
adrenal gland	100%	2642.90	258 / 258	93%	24.86	214 / 230
liver	100%	1164.76	225 / 226	52%	9.85	210 / 406
adipose	100%	3467.84	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3844.98	1335 / 1335	0%	0	0 / 0
spleen	100%	2271.89	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	34.66	45 / 45
ureter	0%	0	0 / 0	100%	34.81	1 / 1
muscle	99%	1788.49	795 / 803	0%	0	0 / 0
heart	96%	1420.06	828 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	35.58	76 / 80
lymph node	0%	0	0 / 0	90%	13.84	26 / 29
peripheral blood	82%	1290.45	764 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042147	Biological process	retrograde transport, endosome to Golgi
GO_0050976	Biological process	detection of mechanical stimulus involved in sensory perception of touch
GO_0071260	Biological process	cellular response to mechanical stimulus
GO_0001726	Cellular component	ruffle
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0005886	Cellular component	plasma membrane
GO_0098782	Molecular function	mechanosensitive potassium channel activity

IV. Literature review

[source]

Gene name	TMEM87A
Protein name	Transmembrane protein 87A Transmembrane protein 87A (Elkin1)
Synonyms	PSEC0094
Description	FUNCTION: May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) . In one study, shown to be a component of a novel mechanoelectrical transduction pathway which is involved in cell adhesion and migration, and is thought to act either as a mechanically activated ion channel or as an accessory protein which modulates an unidentified mechanically activated ion channel . In another study, neither basal nor mechanically activated channel activity has been observed and, based on structural similarity with WLS, has been suggested to function as a trafficking chaperone for membrane-associated cargo . .
Accessions	ENST00000561578.5 ENST00000568432.1 ENST00000566014.2 ENST00000563371.5 ENST00000568400.5 ENST00000566474.5 ENST00000704761.1 H3BTS6 ENST00000569075.5 ENST00000448392.6 H3BUZ1 H3BSZ0 A0A994J4W5 ENST00000389834.9 [Q8NBN3-1] H3BRG0 H3BPJ4 H3BMU0 Q8NBN3 H3BM87 A0A994J7M5 ENST00000704760.1 ENST00000307216.10 [Q8NBN3-2]

TMEM87A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review