TBRG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_1990173Biological processprotein localization to nucleoplasm
GO_0050821Biological processprotein stabilization
GO_0006260Biological processDNA replication
GO_0051726Biological processregulation of cell cycle
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTBRG1
Protein nameTransforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)
Transforming growth factor beta regulator 1
TBRG1 protein
TBRG1 protein (cDNA FLJ25020 fis, clone CBL01662)
SynonymsNIAM
DescriptionFUNCTION: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. .

AccessionsE9PI10
Q3YBR2
Q05BL0
ENST00000529543.5
F8W6N5
Q6GPH2
Q96LV8
ENST00000531667.5
ENST00000284290.8
ENST00000530731.5
ENST00000441174.8 [Q3YBR2-1]
E9PK87