TAGAP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	31 studies	31% ± 12%	Explore
B cell	29 studies	34% ± 13%	Explore
CD8-positive, alpha-beta T cell	28 studies	30% ± 9%	Explore
CD4-positive, alpha-beta T cell	27 studies	32% ± 12%	Explore
T cell	21 studies	30% ± 14%	Explore
naive B cell	20 studies	39% ± 15%	Explore
memory B cell	19 studies	35% ± 15%	Explore
regulatory T cell	19 studies	37% ± 14%	Explore
mature NK T cell	18 studies	31% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	29% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	28% ± 12%	Explore
gamma-delta T cell	14 studies	30% ± 11%	Explore
non-classical monocyte	14 studies	28% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	31% ± 16%	Explore
classical monocyte	13 studies	25% ± 8%	Explore
mucosal invariant T cell	12 studies	36% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	28% ± 9%	Explore
macrophage	9 studies	19% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	28% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	36% ± 14%	Explore
conventional dendritic cell	8 studies	31% ± 12%	Explore
dendritic cell	7 studies	24% ± 6%	Explore
monocyte	7 studies	21% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	34% ± 16%	Explore
innate lymphoid cell	6 studies	28% ± 7%	Explore
plasma cell	6 studies	26% ± 8%	Explore
plasmacytoid dendritic cell	6 studies	21% ± 2%	Explore
precursor B cell	6 studies	42% ± 13%	Explore
T follicular helper cell	6 studies	32% ± 15%	Explore
neutrophil	5 studies	24% ± 5%	Explore
leukocyte	5 studies	29% ± 10%	Explore
immature B cell	5 studies	58% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	39% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	26% ± 5%	Explore
CD4-positive helper T cell	4 studies	32% ± 15%	Explore
myeloid cell	4 studies	25% ± 9%	Explore
T-helper 17 cell	4 studies	42% ± 18%	Explore
microglial cell	4 studies	21% ± 6%	Explore
plasmablast	4 studies	22% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	25% ± 6%	Explore
lymphocyte	3 studies	19% ± 5%	Explore
germinal center B cell	3 studies	29% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	27% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	41% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	32% ± 13%	Explore
double negative thymocyte	3 studies	25% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	28% ± 8%	Explore
lung	4 studies	20% ± 3%	Explore
lymph node	3 studies	35% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	866.82	577 / 578	87%	7.71	1010 / 1155
breast	83%	222.25	383 / 459	87%	7.20	968 / 1118
uterus	91%	626.14	154 / 170	59%	3.29	269 / 459
stomach	77%	150.96	278 / 359	71%	4.71	204 / 286
intestine	83%	522.77	799 / 966	61%	3.77	322 / 527
thymus	73%	202.94	476 / 653	65%	5.66	395 / 605
bladder	76%	273.95	16 / 21	54%	3.31	270 / 504
brain	41%	102.52	1076 / 2642	88%	6.72	621 / 705
kidney	45%	134.90	40 / 89	81%	6.74	730 / 901
esophagus	60%	102.85	872 / 1445	65%	3.58	119 / 183
ovary	64%	110.94	115 / 180	58%	2.63	251 / 430
prostate	75%	147.33	184 / 245	47%	2.24	234 / 502
adrenal gland	93%	228.05	240 / 258	22%	0.98	51 / 230
skin	42%	66.64	759 / 1809	63%	6.14	297 / 472
lymph node	0%	0	0 / 0	100%	48.99	29 / 29
spleen	100%	2823.01	241 / 241	0%	0	0 / 0
peripheral blood	97%	4852.43	901 / 929	0%	0	0 / 0
adipose	93%	337.02	1114 / 1204	0%	0	0 / 0
pancreas	13%	17.66	43 / 328	77%	5.88	137 / 178
liver	62%	102.32	139 / 226	24%	1.18	97 / 406
tonsil	0%	0	0 / 0	84%	10.37	38 / 45
blood vessel	61%	153.18	814 / 1335	0%	0	0 / 0
heart	33%	55.29	288 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	11%	0.47	9 / 80
muscle	3%	3.64	25 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007165	Biological process	signal transduction
GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0035023	Biological process	regulation of Rho protein signal transduction
GO_0005829	Cellular component	cytosol
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0005515	Molecular function	protein binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	TAGAP
Protein name	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein) T cell activation RhoGTPase activating protein
Synonyms	TAGAP1 FKSG15
Description	FUNCTION: May function as a GTPase-activating protein and may play important roles during T-cell activation. .
Accessions	ENST00000367066.8 [Q8N103-1] ENST00000326965.7 [Q8N103-2] Q8N103 A0A2R8YEB9 ENST00000642909.1 ENST00000338313.5 [Q8N103-4]

TAGAP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review