SS18L2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	27 studies	22% ± 6%	Explore
natural killer cell	27 studies	20% ± 6%	Explore
CD4-positive, alpha-beta T cell	25 studies	23% ± 5%	Explore
CD8-positive, alpha-beta T cell	24 studies	23% ± 5%	Explore
T cell	20 studies	21% ± 4%	Explore
regulatory T cell	19 studies	24% ± 3%	Explore
memory B cell	18 studies	22% ± 5%	Explore
naive B cell	14 studies	21% ± 5%	Explore
gamma-delta T cell	13 studies	26% ± 9%	Explore
mature NK T cell	12 studies	21% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	26% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	20% ± 3%	Explore
mucosal invariant T cell	10 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	22% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	21% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	23% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	25% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	23% ± 2%	Explore
conventional dendritic cell	7 studies	26% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 8%	Explore
T follicular helper cell	7 studies	23% ± 4%	Explore
endothelial cell	6 studies	23% ± 6%	Explore
hematopoietic precursor cell	5 studies	24% ± 10%	Explore
non-classical monocyte	5 studies	26% ± 9%	Explore
plasma cell	5 studies	26% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	25% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	27% ± 9%	Explore
innate lymphoid cell	5 studies	22% ± 4%	Explore
endothelial cell of lymphatic vessel	5 studies	20% ± 4%	Explore
plasmacytoid dendritic cell	5 studies	23% ± 5%	Explore
plasmablast	4 studies	37% ± 16%	Explore
classical monocyte	4 studies	24% ± 6%	Explore
exhausted T cell	4 studies	29% ± 3%	Explore
epithelial cell	4 studies	46% ± 17%	Explore
T-helper 17 cell	4 studies	25% ± 6%	Explore
leukocyte	3 studies	24% ± 6%	Explore
immature B cell	3 studies	21% ± 2%	Explore
precursor B cell	3 studies	25% ± 6%	Explore
ciliated cell	3 studies	31% ± 7%	Explore
germinal center B cell	3 studies	28% ± 3%	Explore
fibroblast	3 studies	23% ± 8%	Explore
glutamatergic neuron	3 studies	31% ± 11%	Explore
dendritic cell	3 studies	43% ± 14%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 9%	Explore
transit amplifying cell	3 studies	22% ± 5%	Explore
basal cell	3 studies	28% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	22% ± 2%	Explore
double negative thymocyte	3 studies	31% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	20% ± 5%	Explore
lung	4 studies	23% ± 3%	Explore
bone marrow	3 studies	17% ± 1%	Explore
brain	3 studies	24% ± 6%	Explore
intestine	3 studies	21% ± 7%	Explore
liver	3 studies	32% ± 18%	Explore
lymph node	3 studies	20% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	515.29	21 / 21	100%	21.69	504 / 504
liver	100%	523.31	226 / 226	100%	13.83	406 / 406
lung	100%	638.67	578 / 578	100%	14.58	1155 / 1155
ovary	100%	565.66	180 / 180	100%	19.12	430 / 430
prostate	100%	1216.27	245 / 245	100%	36.81	502 / 502
skin	100%	691.13	1809 / 1809	100%	14.89	472 / 472
stomach	100%	539.62	359 / 359	100%	16.35	286 / 286
thymus	100%	689.85	653 / 653	100%	16.78	605 / 605
uterus	100%	446.50	170 / 170	100%	22.48	459 / 459
brain	100%	943.98	2641 / 2642	100%	18.12	705 / 705
esophagus	100%	468.17	1444 / 1445	100%	13.26	183 / 183
kidney	100%	617.60	89 / 89	100%	9.32	900 / 901
intestine	100%	532.63	966 / 966	100%	17.14	525 / 527
adrenal gland	100%	504.59	258 / 258	100%	11.72	229 / 230
breast	100%	712.73	459 / 459	99%	19.19	1112 / 1118
pancreas	100%	371.26	327 / 328	99%	15.76	177 / 178
adipose	100%	608.86	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	9.23	80 / 80
lymph node	0%	0	0 / 0	100%	49.48	29 / 29
spleen	100%	965.29	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	16.75	45 / 45
ureter	0%	0	0 / 0	100%	27.00	1 / 1
blood vessel	100%	437.05	1331 / 1335	0%	0	0 / 0
heart	98%	352.29	847 / 861	0%	0	0 / 0
muscle	96%	287.59	772 / 803	0%	0	0 / 0
peripheral blood	94%	699.27	877 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0