SRP19 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	23 studies	24% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	28% ± 6%	Explore
CD8-positive, alpha-beta T cell	11 studies	26% ± 9%	Explore
B cell	10 studies	27% ± 9%	Explore
CD4-positive, alpha-beta T cell	10 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	10 studies	29% ± 6%	Explore
regulatory T cell	10 studies	24% ± 5%	Explore
endothelial cell	10 studies	25% ± 8%	Explore
fibroblast	10 studies	23% ± 7%	Explore
gamma-delta T cell	10 studies	24% ± 10%	Explore
mature NK T cell	9 studies	23% ± 5%	Explore
plasmablast	8 studies	48% ± 22%	Explore
memory B cell	8 studies	18% ± 1%	Explore
smooth muscle cell	8 studies	18% ± 2%	Explore
plasma cell	7 studies	33% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	27% ± 6%	Explore
conventional dendritic cell	7 studies	30% ± 16%	Explore
epithelial cell	7 studies	37% ± 20%	Explore
T cell	7 studies	19% ± 5%	Explore
ciliated cell	7 studies	32% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	27% ± 10%	Explore
classical monocyte	6 studies	30% ± 10%	Explore
naive B cell	6 studies	20% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	24% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	25% ± 8%	Explore
non-classical monocyte	6 studies	31% ± 11%	Explore
macrophage	6 studies	23% ± 8%	Explore
mast cell	6 studies	22% ± 5%	Explore
basal cell	6 studies	28% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	30% ± 10%	Explore
mucosal invariant T cell	5 studies	24% ± 2%	Explore
T follicular helper cell	5 studies	18% ± 1%	Explore
pericyte	5 studies	20% ± 3%	Explore
endothelial cell of vascular tree	5 studies	20% ± 3%	Explore
dendritic cell	5 studies	32% ± 20%	Explore
pancreatic A cell	4 studies	40% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	25% ± 5%	Explore
precursor B cell	4 studies	23% ± 1%	Explore
myeloid cell	4 studies	28% ± 11%	Explore
pro-B cell	4 studies	20% ± 0%	Explore
retina horizontal cell	4 studies	21% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	23% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	32% ± 10%	Explore
endothelial cell of artery	4 studies	19% ± 2%	Explore
endothelial cell of lymphatic vessel	4 studies	21% ± 5%	Explore
oligodendrocyte	4 studies	24% ± 8%	Explore
oligodendrocyte precursor cell	4 studies	22% ± 7%	Explore
type B pancreatic cell	3 studies	48% ± 7%	Explore
leukocyte	3 studies	28% ± 4%	Explore
hematopoietic precursor cell	3 studies	31% ± 12%	Explore
lymphocyte	3 studies	25% ± 8%	Explore
myofibroblast cell	3 studies	21% ± 1%	Explore
immature B cell	3 studies	19% ± 1%	Explore
retinal cone cell	3 studies	24% ± 3%	Explore
germinal center B cell	3 studies	22% ± 2%	Explore
capillary endothelial cell	3 studies	18% ± 2%	Explore
innate lymphoid cell	3 studies	25% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	30% ± 8%	Explore
neuron	3 studies	29% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 7%	Explore
astrocyte	3 studies	28% ± 8%	Explore
glutamatergic neuron	3 studies	50% ± 19%	Explore
goblet cell	3 studies	28% ± 8%	Explore
T-helper 17 cell	3 studies	22% ± 5%	Explore
secretory cell	3 studies	31% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	30% ± 9%	Explore
lung	6 studies	29% ± 13%	Explore
pancreas	4 studies	37% ± 10%	Explore
brain	4 studies	44% ± 15%	Explore
intestine	4 studies	20% ± 7%	Explore
liver	4 studies	26% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1509.30	1445 / 1445	100%	3.34	183 / 183
uterus	100%	1441.60	170 / 170	100%	3.83	459 / 459
lung	100%	1522.20	578 / 578	100%	3.16	1153 / 1155
breast	100%	1708.81	459 / 459	100%	4.54	1116 / 1118
prostate	100%	2185.66	245 / 245	100%	4.87	501 / 502
ovary	100%	1067.38	180 / 180	100%	3.19	429 / 430
brain	100%	1419.86	2634 / 2642	100%	5.13	705 / 705
thymus	100%	1959.70	653 / 653	100%	4.32	603 / 605
pancreas	100%	1504.75	328 / 328	99%	3.16	177 / 178
liver	100%	1638.48	226 / 226	99%	2.80	402 / 406
bladder	100%	1372.24	21 / 21	99%	3.10	499 / 504
adrenal gland	100%	2047.51	258 / 258	99%	4.38	227 / 230
stomach	100%	1316.89	359 / 359	98%	3.14	279 / 286
intestine	100%	1492.89	966 / 966	98%	3.06	514 / 527
kidney	100%	1395.16	89 / 89	96%	2.54	862 / 901
skin	100%	1379.59	1808 / 1809	94%	3.14	442 / 472
adipose	100%	1660.72	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	4.17	29 / 29
spleen	100%	1825.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	3.25	45 / 45
ureter	0%	0	0 / 0	100%	1.67	1 / 1
blood vessel	100%	1496.19	1333 / 1335	0%	0	0 / 0
muscle	100%	1222.79	800 / 803	0%	0	0 / 0
heart	99%	1058.93	849 / 861	0%	0	0 / 0
peripheral blood	84%	937.94	776 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	65%	1.51	52 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006613	Biological process	cotranslational protein targeting to membrane
GO_0006617	Biological process	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO_0005730	Cellular component	nucleolus
GO_0005786	Cellular component	signal recognition particle, endoplasmic reticulum targeting
GO_0016604	Cellular component	nuclear body
GO_0005829	Cellular component	cytosol
GO_0048500	Cellular component	signal recognition particle
GO_0043022	Molecular function	ribosome binding
GO_0008312	Molecular function	7S RNA binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	SRP19
Protein name	Signal recognition particle 19 kDa protein Signal recognition particle 19 kDa protein (SRP19)
Synonyms	hCG_2039564 hCG_2040106
Description	FUNCTION: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of SRP54 to the SRP complex (By similarity). .
Accessions	ENST00000445150.3 A0A2U3TZN1 ENST00000621420.5 ENST00000503445.5 ENST00000506997.2 ENST00000391338.3 A0A087WYR0 A0A2R8Y4M3 ENST00000505459.6 [P09132-1] ENST00000282999.7 [P09132-2] P09132 A0A087WWU9 ENST00000515463.1 [P09132-3] D6RBG4

SRP19 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review